CAS 64-75-5

(-)-Cloridrato de tetraciclina

Descrição:

(-)-Cloridrato de tetraciclina é um antibiótico de amplo espectro pertencente à classe das tetraciclinas, utilizado principalmente para tratar várias infecções bacterianas. É caracterizado por sua complexa estrutura policíclica, que inclui quatro anéis fundidos, contribuindo para sua capacidade de inibir a síntese de proteínas nas bactérias ao se ligar à subunidade ribossomal 30S. Este composto é tipicamente apresentado como um sal de cloridrato, melhorando sua solubilidade em água. (-)-Cloridrato de tetraciclina exibe uma cor amarela a laranja e é sensível à luz, o que pode levar à degradação. É eficaz contra uma ampla gama de bactérias gram-positivas e gram-negativas, bem como alguns protozoários. A substância também é conhecida por suas propriedades anti-inflamatórias e às vezes é usada no tratamento da acne e outras condições de pele. No entanto, seu uso pode levar a efeitos colaterais, incluindo distúrbios gastrointestinais e fotossensibilidade. Devido ao seu potencial de causar descoloração dos dentes em crianças, seu uso geralmente é evitado em mulheres grávidas e crianças pequenas. O armazenamento adequado longe da luz e da umidade é essencial para manter sua estabilidade e eficácia.

Fórmula: C₂₂H₂₄N₂O₈·ClH

InChI: InChI=1S/C22H24N2O8.ClH/c1-21(31)8-5-4-6-11(25)12(8)16(26)13-9(21)7-10-15(24(2)3)17(27)14(20(23)30)19(29)22(10,32)18(13)28;/h4-6,9-10,15,25,27-28,31-32H,7H2,1-3H3,(H2,23,30);1H/t9-,10-,15-,21+,22-;/m0./s1

Chave InChI: InChIKey=XMEVHPAGJVLHIG-FMZCEJRJSA-N

SMILES: O[C@@]12[C@@](C[C@]3(C(=C1O)C(=O)C=4C([C@@]3(C)O)=CC=CC4O)[H])([C@H](N(C)C)C(O)=C(C(N)=O)C2=O)[H].Cl

Sinónimos:

• (2E,6S,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-6,10,11,12a-tetrahydroxy-6-methyl-4a,5a,6,12a-tetrahydrotetracene-1,3,12(2H,4H,5H)-trione hydrochloride
• (2Z,4S,4aS,5aS,6S,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-6,10,11,12a-tetrahydroxy-6-methyl-4a,5a,6,12a-tetrahydrotetracene-1,3,12(2H,4H,5H)-trione hydrochloride
• 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, hydrochloride (1:1), (4S,4aS,5aS,6S,12aS)-
• 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrochloride
• 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrochloride, (4S,4aS,5aS,6S,12aS)-
• 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrochloride, [4S-(4α,4aα,5aα,6β,12aα)]-
• 4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthalenecarboxamide hydrochloride
• 4-(Dimethylamino)-3,6,10,12,12A-Pentahydroxy-6-Methyl-1,11-Dioxo-1,4,4A,5,5A,6,11,12A-Octahydrotetracene-2-Carboxamide Hydrochloride (1:1)
• Achro
• Achromycin hydrochloride
• Ala-Tet
• Ambracyn
• Bristaciclina
• Bristacycline
• Cancycline-250
• Cefracycline
• Criseociclina
• Cyclopar
• Diocyclin
• Dumocyclin
• Helvecyclin
• Heromycin
• Hostacyclin
• Hostacycline
• Imex
• Laudin
• Medamycin
• Neocycline B
• Paltet
• Panmycin hydrochloride
• Partrex
• Polycycline hydrochloride
• Polyotic ointment
• Purocyclina
• Quadracyclin
• Remicyclin
• Riocyclin
• Ro-Cycline
• Robitet
• Sanclomycine
• Steclin
• Subamycin
• Sumycin
• Supramycin
• Sustamycin
• Talcin
• Tefilin
• Tet-Cy
• TetraSURE
• Tetrabakat
• Tetrabid
• Tetrablet
• Tetrabon
• Tetracaps
• Tetrachel
• Tetraciclina, Clorhidrato
• Tetracompren
• Tetracycline chlorohydrate
• Tetracycline hcl
• Tetracycline, chlorhydrate
• Tetracyclinhydrochlorid
• Tetracyklin
• Tetracyn
• Tetrakap
• Tetralution
• Tetramavan
• Tetrosol
• Topicycline
• Totomycin
• Triphacyclin
• Unicin
• Vetquamycin 324

Tetracycline Hydrochloride

CAS: 60-54-8, 64-75-5

Fórmula: C₂₂H₂₄N₂O₈·HCl

Pureza: >98.0%(T)

Cor e Forma: Light yellow to Amber to Dark green powder to crystal

Peso molecular: 480.90

Ref: 3B-T2525

Tetracycline hydrochloride, 96%

CAS: 64-75-5

Tetracycline hydrochloride, 64-75-5, the hydrochloride salt of the napthacene tetracycline, is a broad-spectrum bacteriostatic antibiotic. Learn more.

Fórmula: C₂₂H₂₅ClN₂O₈

Pureza: 96%

Cor e Forma: Yellow, Crystals or powder or crystalline powder

Peso molecular: 480.90

Ref: 02-B21408

Tetracycline Hydrochloride

CAS: 64-75-5

Cor e Forma: Neat

Ref: 61-FOR0452.00

TETRACYCLINE HYDROCHLORIDE RS

CAS: 64-75-5

TETRACYCLINE HYDROCHLORIDE RS

Fórmula: C₂₂H₂₅ClN₂O₈

Peso molecular: 480.8955

Ref: 41-ICRS0429

Tetracycline hydrochloride

CAS: 64-75-5

Tetracycline hydrochloride

Fórmula: C₂₂H₂₄N₂O₈HCl

Pureza: 97.5%

Cor e Forma: Yellow Solid

Peso molecular: 480.12994

Ref: 47-480

TETRACYCLINE HYDROCHLORIDE CRS

CAS: 64-75-5

TETRACYCLINE HYDROCHLORIDE CRS

Ref: 41-T0600000

Tetracycline Hydrochloride

CAS: 64-75-5

Tetracyclines and their derivatives; salts thereof

Fórmula: C₂₂H₂₄N₂O₈·ClH

Cor e Forma: Yellow Powder

Peso molecular: 480.12994

Ref: 45-1651009

Tetracycline hydrochloride

CAS: 64-75-5

Tetracycline hydrochloride is a broad-spectrum antibiotic, blocking protein synthesis in bacteria and used in bone histomorphometry.

Fórmula: C₂₂H₂₄N₂O₈·HCl

Pureza: 97.85% - 99.64%

Cor e Forma: Off-White Powder

Peso molecular: 480.90

Ref: TM-T0912

Tetracycline hydrochloride, BP, Ph. Eur. grade

CAS: 64-75-5

Fórmula: C₂₂H₂₄N₂O₈·HCl

Pureza: (HPLC) 95.0 - 102.0 %

Cor e Forma: Yellow crystalline powder

Peso molecular: 480.91

Ref: 7W-GP9934

Tetracycline hydrochloride

CAS: 64-75-5

Tetracycline hydrochloride

Pureza: ≥95%

Peso molecular: 480.9g/mol

Ref: 54-BUP18425

Tetracycline hydrochloride

CAS: 64-75-5

Tetracycline hydrochloride

Fórmula: C₂₂H₂₄N₂O₈·ClH

Pureza: By hplc: 97.7% by area (Typical Value in Batch COA)

Cor e Forma: yellow powder

Peso molecular: 480.89549g/mol

Ref: 54-BIT0150

Tetracycline hydrochloride

CAS: 64-75-5

Fórmula: C₂₂H₂₄N₂O₈·HCl

Pureza: ≥ 95.0%

Cor e Forma: Yellow powder

Peso molecular: 480.91

Ref: 7W-GA4323

Tetracycline HCl (Oxytetracycline EP Impurity B HCl)

CAS: 64-75-5

Fórmula: C₂₂H₂₄N₂O₈·HCl

Cor e Forma: Pale Yellow Solid

Peso molecular: 444.45 36.46

Ref: 4Z-T-401

Tetracycline hydrochloride

CAS: 64-75-5

Pureza: >95%

Peso molecular: 480.896

Ref: FT-D14906

Tetracycline Hydrochloride

Produto Controlado

CAS: 64-75-5

Fórmula: C₂₂H₂₄N₂O₈·ClH

Cor e Forma: Yellow

Peso molecular: 480.90

Ref: 86-MM0452.00

Tetracycline hydrochloride

Produto Controlado

CAS: 64-75-5

Fórmula: C₂₂H₂₄N₂O₈·ClH

Cor e Forma: Neat

Peso molecular: 480.90

Ref: 04-C17396150

PharmaVetResiMix 5 Tetracyclines-v10 10 µg/mL in Methanol

Produto Controlado

CAS: 101342-45-4, 14206-58-7, 179471-95-5, 2058-46-0, 23313-80-6, 24390-14-5, 41411-66-9, 64-72-2, 64-73-3, 64-75-5

Cor e Forma: Mixture

Ref: 04-A30000035ME

Tetracycline hydrochloride 100 µg/mL in Acetonitrile

CAS: 64-75-5

Fórmula: C₂₂H₂₄N₂O₈·ClH

Cor e Forma: Single Solution

Peso molecular: 480.90

Ref: 04-A17396150AL-100

Tetracycline hydrochloride, USP grade

CAS: 64-75-5

Fórmula: C₂₂H₂₄N₂O₈·HCl

Cor e Forma: Yellow powder

Peso molecular: 480.91

Ref: 7W-GP3828

Tetracycline Hydrochloride

CAS: 64-75-5

Applications Antibiotic substance produced by Streptomyces spp. Antiamebic; antibacterial; antirickettsial.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Weiss, et al.: Antibiot. Chemother., 7, 374 (1957), Goldenthal, E.I., et al.: Toxicol. Appl. Pharmacol., 18, 185 (1971),

Fórmula: C₂₂H₂₄N₂O₈·ClH

Cor e Forma: Neat

Peso molecular: 480.90

Ref: TR-T291400

Tetracycline Hydrochloride

CAS: 64-75-5

Fórmula: C₂₂H₂₄N₂O₈HCl

Peso molecular: 444.4 : 36.46

Ref: ST-EA-CP-T200003

Tetracycline hydrochloride

CAS: 64-75-5

Antibiotic of tetracycline class; protein synthesis inhibitor

Fórmula: C₂₂H₂₅ClN₂O₈

Cor e Forma: Yellow Powder

Peso molecular: 480.9 g/mol

Ref: 3D-AT28073

Tetracycline hydrochloride - USP

CAS: 64-75-5

Tetracycline hydrochloride - USP is a broad-spectrum antibiotic, which is a synthetic derivative of chlortetracycline produced from the bacterium *Streptomyces aureofaciens*. It functions by inhibiting protein synthesis in bacteria, specifically binding to the 30S ribosomal subunit. This action prevents the attachment of aminoacyl-tRNA to the mRNA-ribosome complex, thereby halting bacterial growth and replication.

Fórmula: C₂₂H₂₅ClN₂O₈

Cor e Forma: Yellow Powder

Peso molecular: 480.9 g/mol

Ref: 3D-AT168330

Tetracycline Hydrochloride (TC) for tissue culture, 95%

CAS: 64-75-5

Fórmula: C₂₂H₂₄N₂O₈·HCl

Pureza: min. 95%

Cor e Forma: Yellow, Crystalline powder

Peso molecular: 480.90

Ref: SR-82175

Tetracycline Hydrochloride (TC), 95%

CAS: 64-75-5

Fórmula: C₂₂H₂₄N₂O₈·HCl

Pureza: min. 95%

Cor e Forma: Yellow, Crystalline powder

Peso molecular: 480.90

Ref: SR-38614

Tetracycline hydrochloride

CAS: 64-75-5

Pureza: 98%

Peso molecular: 479.89

Ref: 10-F951532

Tetracycline hydrochloride, Antibiotic for Culture Media Use Only

CAS: 64-75-5

Tetracycline hydrochloride is a broad-spectrum antibiotic and is an electron transfer agent. It has been shown to be effective against bacterial infections in humans and has been used in cultures for the prevention of bacterial contamination. As an electron transfer agent, it is used in electron microscopy to study the surface of biological cells. Tetracycline hydrochloride enters bacterial cells by diffusion and interacts with the cytoplasmic membrane, where it induces a redox reaction that leads to cell death. The efficacy of tetracycline hydrochloride in treating candida albicans (yeast) was studied using in-vitro activity and showed that carboxymethyl chitosan nanoparticles were able to enhance the treatment efficiency.

Fórmula: C₂₂H₂₅ClN₂O₈

Pureza: Min. 88.0 Area-%

Peso molecular: 480.90 g/mol

Ref: 3D-T-1961

Tetracycline hydrochloride (10mg/ml)

CAS: 64-75-5

Tetracycline hydrochloride (10mg/ml)

Cor e Forma: Solution

Peso molecular: 494.92g/mol

Ref: 54-BIG1033