CAS 64-75-5

(-)-Cloridrato de tetraciclina

Descrição:

(-)-Cloridrato de tetraciclina é um antibiótico de amplo espectro pertencente à classe das tetraciclinas, utilizado principalmente para tratar várias infecções bacterianas. É caracterizado por sua complexa estrutura policíclica, que inclui quatro anéis fundidos, contribuindo para sua capacidade de inibir a síntese de proteínas nas bactérias ao se ligar à subunidade ribossomal 30S. Este composto é tipicamente apresentado como um sal de cloridrato, melhorando sua solubilidade em água. (-)-Cloridrato de tetraciclina exibe uma cor amarela a laranja e é sensível à luz, o que pode levar à degradação. É eficaz contra uma ampla gama de bactérias gram-positivas e gram-negativas, bem como alguns protozoários. A substância também é conhecida por suas propriedades anti-inflamatórias e às vezes é usada no tratamento da acne e outras condições de pele. No entanto, seu uso pode levar a efeitos colaterais, incluindo distúrbios gastrointestinais e fotossensibilidade. Devido ao seu potencial de causar descoloração dos dentes em crianças, seu uso geralmente é evitado em mulheres grávidas e crianças pequenas. O armazenamento adequado longe da luz e da umidade é essencial para manter sua estabilidade e eficácia.

Fórmula: C₂₂H₂₄N₂O₈·ClH

InChI: InChI=1S/C22H24N2O8.ClH/c1-21(31)8-5-4-6-11(25)12(8)16(26)13-9(21)7-10-15(24(2)3)17(27)14(20(23)30)19(29)22(10,32)18(13)28;/h4-6,9-10,15,25,27-28,31-32H,7H2,1-3H3,(H2,23,30);1H/t9-,10-,15-,21+,22-;/m0./s1

Chave InChI: InChIKey=XMEVHPAGJVLHIG-FMZCEJRJSA-N

SMILES: O[C@@]12[C@@](C[C@]3(C(=C1O)C(=O)C=4C([C@@]3(C)O)=CC=CC4O)[H])([C@H](N(C)C)C(O)=C(C(N)=O)C2=O)[H].Cl

Sinónimos:

• (2E,6S,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-6,10,11,12a-tetrahydroxy-6-methyl-4a,5a,6,12a-tetrahydrotetracene-1,3,12(2H,4H,5H)-trione hydrochloride
• (2Z,4S,4aS,5aS,6S,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-6,10,11,12a-tetrahydroxy-6-methyl-4a,5a,6,12a-tetrahydrotetracene-1,3,12(2H,4H,5H)-trione hydrochloride
• 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, hydrochloride (1:1), (4S,4aS,5aS,6S,12aS)-
• 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrochloride
• 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrochloride, (4S,4aS,5aS,6S,12aS)-
• 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrochloride, [4S-(4α,4aα,5aα,6β,12aα)]-
• 4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthalenecarboxamide hydrochloride
• 4-(Dimethylamino)-3,6,10,12,12A-Pentahydroxy-6-Methyl-1,11-Dioxo-1,4,4A,5,5A,6,11,12A-Octahydrotetracene-2-Carboxamide Hydrochloride (1:1)
• Achro
• Achromycin hydrochloride
• Ala-Tet
• Ambracyn
• Bristaciclina
• Bristacycline
• Cancycline-250
• Cefracycline
• Criseociclina
• Cyclopar
• Diocyclin
• Dumocyclin
• Helvecyclin
• Heromycin
• Hostacyclin
• Hostacycline
• Imex
• Laudin
• Medamycin
• Neocycline B
• Paltet
• Panmycin hydrochloride
• Partrex
• Polycycline hydrochloride
• Polyotic ointment
• Purocyclina
• Quadracyclin
• Remicyclin
• Riocyclin
• Ro-Cycline
• Robitet
• Sanclomycine
• Steclin
• Subamycin
• Sumycin
• Supramycin
• Sustamycin
• Talcin
• Tefilin
• Tet-Cy
• TetraSURE
• Tetrabakat
• Tetrabid
• Tetrablet
• Tetrabon
• Tetracaps
• Tetrachel
• Tetraciclina, Clorhidrato
• Tetracompren
• Tetracycline chlorohydrate
• Tetracycline hcl
• Tetracycline, chlorhydrate
• Tetracyclinhydrochlorid
• Tetracyklin
• Tetracyn
• Tetrakap
• Tetralution
• Tetramavan
• Tetrosol
• Topicycline
• Totomycin
• Triphacyclin
• Unicin
• Vetquamycin 324

Tetracycline Hydrochloride

CAS: 64-75-5

Fórmula: C₂₂H₂₄N₂O₈HCl

Peso molecular: 444.4 : 36.46

Ref: ST-EA-CP-T200003

Tetracycline hydrochloride

CAS: 64-75-5

Antibiotic of tetracycline class; protein synthesis inhibitor

Fórmula: C₂₂H₂₅ClN₂O₈

Cor e Forma: Yellow Powder

Peso molecular: 480.9 g/mol

Ref: 3D-AT28073

Tetracycline hydrochloride - USP

CAS: 64-75-5

Tetracycline hydrochloride - USP is a broad-spectrum antibiotic, which is a synthetic derivative of chlortetracycline produced from the bacterium *Streptomyces aureofaciens*. It functions by inhibiting protein synthesis in bacteria, specifically binding to the 30S ribosomal subunit. This action prevents the attachment of aminoacyl-tRNA to the mRNA-ribosome complex, thereby halting bacterial growth and replication.

Fórmula: C₂₂H₂₅ClN₂O₈

Cor e Forma: Yellow Powder

Peso molecular: 480.9 g/mol

Ref: 3D-AT168330

Tetracycline Hydrochloride (TC) for tissue culture, 95%

CAS: 64-75-5

Fórmula: C₂₂H₂₄N₂O₈·HCl

Pureza: min. 95%

Cor e Forma: Yellow, Crystalline powder

Peso molecular: 480.90

Ref: SR-82175

Tetracycline Hydrochloride (TC), 95%

CAS: 64-75-5

Fórmula: C₂₂H₂₄N₂O₈·HCl

Pureza: min. 95%

Cor e Forma: Yellow, Crystalline powder

Peso molecular: 480.90

Ref: SR-38614

Tetracycline hydrochloride

CAS: 64-75-5

Pureza: 98%

Peso molecular: 479.89

Ref: 10-F951532

Tetracycline hydrochloride, Antibiotic for Culture Media Use Only

CAS: 64-75-5

Tetracycline hydrochloride is a broad-spectrum antibiotic and is an electron transfer agent. It has been shown to be effective against bacterial infections in humans and has been used in cultures for the prevention of bacterial contamination. As an electron transfer agent, it is used in electron microscopy to study the surface of biological cells. Tetracycline hydrochloride enters bacterial cells by diffusion and interacts with the cytoplasmic membrane, where it induces a redox reaction that leads to cell death. The efficacy of tetracycline hydrochloride in treating candida albicans (yeast) was studied using in-vitro activity and showed that carboxymethyl chitosan nanoparticles were able to enhance the treatment efficiency.

Fórmula: C₂₂H₂₅ClN₂O₈

Pureza: Min. 88.0 Area-%

Peso molecular: 480.90 g/mol

Ref: 3D-T-1961

Tetracycline hydrochloride (10mg/ml)

CAS: 64-75-5

Tetracycline hydrochloride (10mg/ml)

Cor e Forma: Solution

Peso molecular: 494.92g/mol

Ref: 54-BIG1033