CAS 641571-11-1

5-(4-Metil-1H-imidazol-1-il)-3-(trifluorometil)benzenamina

Descrição:

5-(4-Metil-1H-imidazol-1-il)-3-(trifluorometil)benzenamina, com o número CAS 641571-11-1, é um composto químico caracterizado por sua estrutura única que inclui um grupo trifluorometílico e uma parte de imidazol. Este composto normalmente exibe propriedades associadas a aminas aromáticas, como solubilidade moderada em solventes orgânicos e reatividade potencial devido à presença do grupo funcional amina. O grupo trifluorometílico aumenta a lipofilicidade e pode influenciar a atividade biológica do composto, tornando-o de interesse na pesquisa farmacêutica. O anel de imidazol contribui para seu potencial como um ligante em química de coordenação e também pode conferir propriedades biológicas específicas, como atividade antimicrobiana ou antifúngica. Além disso, a presença do grupo metila no anel de imidazol pode afetar as propriedades estéricas e eletrônicas do composto, influenciando sua reatividade e interações com outras moléculas. No geral, as características estruturais únicas deste composto o tornam um assunto de interesse em vários campos, incluindo química medicinal e ciência dos materiais.

Fórmula: C₁₁H₁₀F₃N₃

InChI: InChI=1S/C11H10F3N3/c1-7-5-17(6-16-7)10-3-8(11(12,13)14)2-9(15)4-10/h2-6H,15H2,1H3

Chave InChI: InChIKey=WWTGXYAJVXKEKL-UHFFFAOYSA-N

SMILES: C(F)(F)(F)C=1C=C(C=C(N)C1)N2C=C(C)N=C2

Sinónimos:

• 1-(3-Amino-5-trifluoromethylphenyl)-4-methylimidazole
• 3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzenamine
• 3-(4-Methyl-1H-imidazol-1-yl)-5-trifluoromethylaniline
• 3-(4-Methyl-imidazol-1-yl)-5-trifluoro-methylphenylamine
• 3-(4-Methyl-imidazole-1-yl)-5-trifluoro methylphenylamine
• 3-(4-Methylimidazol-1-yl)-5-trifluoromethylphenylamine
• 3-(trifluoromethyl)-5-(4-methyl-1H-imidazol-1-yl)benzenamine
• 5-(4-Methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)benzenamine
• 5-(4-Methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)benzeneamine
• Benzenamine, 3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)-

3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline

CAS: 641571-11-1

Fórmula: C₁₁H₁₀F₃N₃

Pureza: >98.0%(GC)(T)

Cor e Forma: White to Light gray to Light yellow powder to crystal

Peso molecular: 241.22

Ref: 3B-M2634

NILOTINIB IMPURITY A CRS

CAS: 641571-11-1

NILOTINIB IMPURITY A CRS

Ref: 41-Y0002103

Nilotinib Related Compound A (3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline)

CAS: 641571-11-1

Compounds containing an unfused imidazole ring, whether or not hydrogenated, in the structure, nesoi

Fórmula: C₁₁H₁₀F₃N₃

Cor e Forma: Beige Powder

Peso molecular: 241.08268

Ref: 45-1463439

3-Amino-5-(4-methyl-1H-imidazol-1-yl)benzotrifluoride

CAS: 641571-11-1

3-Amino-5-(4-methyl-1H-imidazol-1-yl)benzotrifluoride

Pureza: 99%

Cor e Forma: Pale Yellow Solid

Peso molecular: 241.21g/mol

Ref: 54-PC6078

Nilotinib EP Impurity A (Nilotinib USP Related Compound A)

CAS: 641571-11-1

Fórmula: C₁₁H₁₀F₃N₃

Cor e Forma: White To Off-White Solid

Peso molecular: 241.22

Ref: 4Z-N-3129

3-(4-Methyl-1H-imidazol-1-yl)-5-trifluoromethylaniline

CAS: 641571-11-1

Cor e Forma: Neat

Ref: 86-MM3374.01

3-(4-Methyl-1H-imidazol-1-yl)-5-trifluoromethylaniline

Produto Controlado

CAS: 641571-11-1

Applications Intermediate in the preparation of Nilotinib.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Zhang, G., et al.: Bioorg. Med. Chem. Lett., 19, 6691 (2009), Seeliger, M., et al.: Cancer Res., 69, 2384 (2009),

Fórmula: C₁₁H₁₀F₃N₃

Cor e Forma: Neat

Peso molecular: 241.21

Ref: TR-M313065

Nilotinib EP Impurity A

CAS: 641571-11-1

Fórmula: C₁₁H₁₀F₃N₃

Peso molecular: 241.22

Ref: ST-EA-CP-N11001

3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline

CAS: 641571-11-1

Fórmula: C₁₁H₁₀F₃N₃

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 241.217

Ref: 10-F078162

3-(4-Methyl-1H-imidazol-1-yl)-5-trifluoromethylaniline

CAS: 641571-11-1

3-(4-Methyl-1H-imidazol-1-yl)-5-trifluoromethylaniline (MTIA) is a diazotization agent that is used in the industrial production of nilotinib, an anti-cancer drug. MTIA reacts with ethyl acetate to form ethyl 3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline, which can then be reacted with hydrochloric acid to produce MTIA hydrochloride. The MTIA hydrochloride can be dissolved in water and used as a diazotization agent. The sequence of these reactions is: 3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline + ethyl acetate → ethyl 3-(4-methyl--1H--

Fórmula: C₁₁H₁₀F₃N₃

Pureza: Min. 98 Area-%

Cor e Forma: Powder

Peso molecular: 241.21 g/mol

Ref: 3D-FM25612