CAS 644-78-0

2-Hidroxicalcona

Descrição:

2-Hidroxicalcona, com o número CAS 644-78-0, é um composto flavonoide caracterizado por suas características estruturais, que incluem uma estrutura de chalcona com um grupo hidroxila na segunda posição do anel aromático. Este composto geralmente aparece como um sólido amarelo pálido e é conhecido por suas potenciais atividades biológicas, incluindo propriedades antioxidantes, anti-inflamatórias e antimicrobianas. É solúvel em solventes orgânicos como etanol e metanol, mas tem solubilidade limitada em água. A presença do grupo hidroxila aumenta sua reatividade e interação com vários alvos biológicos. 2-Hidroxicalcona é frequentemente estudado no contexto da química medicinal e da pesquisa de produtos naturais devido à sua capacidade de modular várias vias bioquímicas. Além disso, serve como precursor para a síntese de outros flavonoides e pode ser utilizado no desenvolvimento de alimentos funcionais e nutracêuticos. Sua estabilidade e reatividade podem ser influenciadas por fatores ambientais, como pH e temperatura, tornando-o um assunto interessante para pesquisas futuras em química sintética e aplicada.

Fórmula: C₁₅H₁₂O₂

InChI: InChI=1/C15H12O2/c16-14-9-5-4-8-13(14)15(17)11-10-12-6-2-1-3-7-12/h1-11,16H/b11-10-

Chave InChI: InChIKey=UDOOPSJCRMKSGL-UHFFFAOYSA-N

SMILES: C(=CC(=O)C1=CC=CC=C1)C2=C(O)C=CC=C2

Sinónimos:

• (2-Hydroxybenzylidene)acetophenone~3-(2-Hydroxyphenyl)-1-phenyl-2-propen-1-one
• (2E)-3-(2-hydroxyphenyl)-1-phenylprop-2-en-1-one
• (2Z)-1-(2-hydroxyphenyl)-3-phenylprop-2-en-1-one
• 1-Phenyl-3-(2-hydroxyphenyl)-2-propenone
• 2-Hydroxychalcone, [(2-Hydroxybenzylidene)- acetopheno
• 2-Propen-1-one, 3-(2-hydroxyphenyl)-1-phenyl-
• 3-(2-Hydroxyphenyl)-1-Phenylprop-2-En-1-One
• 3-(2-Hydroxyphenyl)-1-phenyl-2-propen-1-one
• 3-(2-Hydroxyphenyl)-1-phenylpropenone
• 3-(o-Hydroxyphenyl)acrylophenone
• Chalcone, 2-hydroxy-
• NSC 37432
• NSC 640539
• Salicylideneacetophenone
• o-Hydroxystyryl phenyl ketone
• 2-Hydroxychalcone
• 2-(2-HYDROXYBENZYLIDENE)ACETOPHENONE
• 2-(2-HYDROXYBENZAL)ACETOPHENONE
• TRANS-2-HYDROXYBENZYLIDENEACETOPHENONE
• 2-Hydroxychalcone, 98+%
• BENZYLIDENE-2-HYDROXYACETOPHENONE
• SALICYLALACETOPHENONE
• α-(o-Hydroxybenzylidene)acetophenone
• o-Hydroxychalcone
• 2-HYDROXYCHALCONE(UNSPECIFIEDISOMER)
• 2-HYDROXYBENZYLIDENE ACETOPHENONE
• TRANS-2-HYDROXYCHALCONE
• HYDROXYCHALCONE, 2-

(E)-2-Hydroxychalcone

CAS: 42224-53-3, 644-78-0

Fórmula: C₁₅H₁₂O₂

Pureza: >98.0%(GC)(T)

Cor e Forma: Light yellow to Amber to Dark green powder to crystal

Peso molecular: 224.26

Ref: 3B-H0234

2-Hydroxychalcone, 98+%

CAS: 644-78-0

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Fórmula: C₁₅H₁₂O₂

Pureza: 98+%

Cor e Forma: Powder, Yellow to green

Peso molecular: 224.26

Ref: 02-A12851

2-Hydroxychalcone

CAS: 644-78-0

2-Hydroxychalcone analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.

Fórmula: C₁₅H₁₂O₂

Pureza: (HPLC) ≥95%

Cor e Forma: Powder

Peso molecular: 224.27

Ref: 11-1270

3-(2-Hydroxyphenyl)-1-phenylprop-2-en-1-one

CAS: 644-78-0

Fórmula: C₁₅H₁₂O₂

Pureza: 95%

Cor e Forma: Solid

Peso molecular: 224.2546

Ref: IN-DA003HFF

2-Hydroxychalcone

CAS: 644-78-0

2-Hydroxychalcone

Fórmula: C₁₅H₁₂O₂

Pureza: 98%

Cor e Forma: yellow powder

Peso molecular: 224.25g/mol

Ref: 54-OR8852

2-Hydroxychalcone

CAS: 644-78-0

2-Hydroxychalcone

Pureza: ≥98%

Peso molecular: 224.25g/mol

Ref: 54-BUP16479

2-Hydroxychalcone

CAS: 644-78-0

2-Hydroxychalcone (2-(2-Hydroxybenzal)Acetophenone) can be used as antiparasitic hit compounds when Methoxylated. It inhibits invasion of breast cancer cells.

Fórmula: C₁₅H₁₂O₂

Pureza: 99.6%

Cor e Forma: Solid

Peso molecular: 224.25

Ref: TM-T7979

2-Hydroxychalcone

CAS: 644-78-0

2-Hydroxychalcone is a chemical compound that has been shown to have hypoglycemic effects in mice and rats. It also inhibits the efflux pump of cancer cells, which prevents the drug from being pumped out of the cell, and thus increases its concentration inside the cell. 2-Hydroxychalcone is structurally similar to epidermal growth factor (EGF). The nitrogen atoms are important for its activity as they can form hydrogen bonds with water molecules and help stabilize the protein's conformation. 2-Hydroxychalcone has been shown to have anti-cancer properties in vitro and in vivo, with a particular effect on prostate cancer cells. It also inhibits tumor growth by reducing the production of insulin-like growth factor 1 (IGF1) levels.

Fórmula: C₁₅H₁₂O₂

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 224.25 g/mol

Ref: 3D-FH43279

2-Hydroxychalcone

CAS: 644-78-0

Fórmula: C₁₅H₁₂O₂

Pureza: 98.0%

Cor e Forma: Solid

Peso molecular: 224.259

Ref: 10-F003115