CAS 64480-66-6

Ácido glicoursodesoxicólico

Descrição:

Ácido glicoursodesoxicólico, com o número CAS 64480-66-6, é um derivado de ácido biliar que desempenha um papel na digestão e absorção de gorduras e vitaminas lipossolúveis no intestino. É um ácido biliar conjugado formado pela conjugação do ácido ursodeoxicólico com glicina. Este composto exibe propriedades anfipáticas, o que significa que possui regiões hidrofílicas e hidrofóbicas, facilitando sua função como detergente na emulsificação de lipídios. Ácido glicoursodesoxicólico é conhecido por seus potenciais efeitos terapêuticos, particularmente no tratamento de doenças hepáticas e dissolução de cálculos biliares. Também pode possuir propriedades citoprotetoras, ajudando a proteger as células do fígado contra danos. Em termos de solubilidade, geralmente é solúvel em água devido aos seus grupos funcionais polares. Sua estrutura molecular inclui um esqueleto esteroide com grupos hidroxila que contribuem para sua atividade biológica. No geral, Ácido glicoursodesoxicólico é significativo tanto em processos fisiológicos quanto em aplicações clínicas potenciais.

Fórmula: C₂₆H₄₃NO₅

InChI: InChI=1S/C26H43NO5/c1-15(4-7-22(30)27-14-23(31)32)18-5-6-19-24-20(9-11-26(18,19)3)25(2)10-8-17(28)12-16(25)13-21(24)29/h15-21,24,28-29H,4-14H2,1-3H3,(H,27,30)(H,31,32)/t15-,16+,17-,18-,19+,20+,21+,24+,25+,26-/m1/s1

Chave InChI: InChIKey=GHCZAUBVMUEKKP-XROMFQGDSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@]([C@]4(C)[C@](C[C@@H]3O)(C[C@H](O)CC4)[H])(CC1)[H])[H])(CC[C@@]2([C@@H](CCC(NCC(O)=O)=O)C)[H])[H]

Sinónimos:

• 2-[[(4R)-4-[(3R,5S,7S,10R,13R,17R)-3,7-Dihydroxy-10,13-Dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-Tetradecahydro-1H-Cyclopenta[A]Phenanthren-17-Yl]Pentanoyl]Amino]Acetic Acid
• 3α,7β-Dihydroxy-5β-cholanoylglycine
• Glycine, N-[(3α,5β,7β)-3,7-dihydroxy-24-oxocholan-24-yl]-
• Glycoursodeoxycholic acid
• Glycylursodeoxycholic acid
• N-(3α,7β-Dihydroxy-5β-cholan-24-oyl)glycine
• N-[(3α,5β,7β)-3,7-Dihydroxy-24-oxocholan-24-yl]glycine
• Ursodeoxycholylglycine
• Glycine ursodeoxycholic acid
• GUDCA
• 3.alpha.,7.beta.-Dihydroxy-5.beta.-cholanoylglycine
• N-Carboxymethyl-3α,7β-dihydroxy-5β-cholan-24-amide
• 3.α.,7.beta.-Dihydroxy-5.beta.-cholanoylglycine
• N-[(3.α.,5.beta.,7.beta.)-3,7-dihydroxy-24-oxocholan-24-yl]Glycine
• N-[(3.alpha.,5.beta.,7.beta.)-3,7-Dihyd
• N-[(3α,5β,7β)-3,7-Dihydroxy-24-oxocholan-24-yl]glycine, Glycylursodeoxycholic acid
• N-[(3.α.,5.beta.,7.beta.)-3,7-Dihyd
• N-[(3.alpha.,5.beta.,7.beta.)-3,7-dihydroxy-24-oxocholan-24-yl]Glycine
• N-(3α,7β-Dihydroxy-24-oxo-5β-cholan-24-yl)glycine
• N-((3alpha,5beta,7beta)-7-Hydroxy-24-oxo-3-(sulfooxy)cholan-24-yl)glycine
• N-(3.α.,7.beta.-Dihydroxy-5.beta.-cholan-24-oyl)glycine
• N-(3.alpha.,7.beta.-Dihydroxy-5.beta.-cholan-24-oyl)glycine
• 3-amino-1-azabicyclo[2.2.2]oct-3-yl diphenylacetate hydrochloride(1:1)
• Glycoursodeoxycholic-d4 Acid

Glycoursodeoxycholic Acid

CAS: 64480-66-6

Fórmula: C₂₆H₄₃NO₅

Pureza: >95.0%(HPLC)(N)

Cor e Forma: White to Almost white powder to crystal

Peso molecular: 449.63

Ref: 3B-G0459

Glycoursodeoxycholic acid

CAS: 64480-66-6

Fórmula: C₂₆H₄₃NO₅

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 449.6233

Ref: IN-DA0036XT

Glycoursodeoxycholic Acid-d7

CAS: 64480-66-6

Fórmula: C₂₆H₃₈D₅NO₅

Peso molecular: 456.67

Ref: 4Z-U-027

Glycoursodeoxycholic acid

CAS: 64480-66-6

Glycoursodeoxycholic acid

Pureza: ≥98%

Peso molecular: 449.62g/mol

Ref: 54-BUP00193

Glycoursodeoxycholic Acid

CAS: 64480-66-6

Fórmula: C₂₆H₄₃NO₅

Cor e Forma: White To Off-White Solid

Peso molecular: 449.63

Ref: 4Z-U-026

Glycoursodeoxycholic acid

CAS: 64480-66-6

Fórmula: C₂₆H₄₃NO₅

Pureza: 95%~99%

Peso molecular: 449.632

Ref: BP-SBP03993

Glycoursodeoxycholic acid

CAS: 64480-66-6

Pureza: 98%

Peso molecular: 449.6319885253906

Ref: 10-F787625

Glycoursodeoxycholic acid

CAS: 64480-66-6

Glycoursodeoxycholic acid, a secondary bile acid-glycine conjugate, is formed by colonic microbes and found in mammalian bile.

Fórmula: C₂₆H₄₃NO₅

Pureza: 99.62% - 99.89%

Cor e Forma: Solid

Peso molecular: 449.62

Ref: TM-T5234

Glycoursodeoxycholic acid

CAS: 64480-66-6

Fórmula: C₂₆H₄₃NO₅

Pureza: ≥ 97.0%

Cor e Forma: White to almost white powder

Peso molecular: 449.62

Ref: 7W-GL1421

Glycoursodeoxycholic Acid-d5

Produto Controlado

CAS: 64480-66-6

Applications Stable labelled metabolite of Ursodeoxycholic Acid, which is used as an anticholelithogenic.

Fórmula: C₂₆H₃₈D₅NO₅

Cor e Forma: Off-White

Peso molecular: 454.65

Ref: TR-G679552

Glycoursodeoxycholic Acid

CAS: 64480-66-6

Applications A metabolite of Ursodeoxycholic Acid, which is used as an anticholelithogenic.

Fórmula: C₂₆H₄₃NO₅

Cor e Forma: White To Off-White

Peso molecular: 449.62

Ref: TR-G679550

Glycoursodeoxycholic acid

CAS: 64480-66-6

Glycoursodeoxycholic acid (GUDCA) is a bile acid that is synthesized from glycine and ursodeoxycholic acid. It has been shown to have an antioxidant effect in a model system of oxidative injury. GUDCA has also been found to attenuate the effects of bile acid on bowel disease, as well as metabolic disorders such as energy metabolism and bile acid homeostasis. GUDCA may be used as a therapeutic treatment for metabolic disorders, including obesity and diabetes. GUDCA may also be effective in treating neurological diseases such as Alzheimer's disease and Parkinson's disease.

Fórmula: C₂₆H₄₃NO₅

Pureza: Min. 96 Area-%

Cor e Forma: White Powder

Peso molecular: 449.62 g/mol

Ref: 3D-FG23694

Glycoursodeoxycholic Acid (GUDCA) extrapure, 97%

CAS: 64480-66-6

Fórmula: C₂₆H₄₃NO₅

Peso molecular: 449.62

Ref: SR-50391

Glycoursodeoxycholic Acid

CAS: 64480-66-6

Fórmula: C₂₆H₄₃NO₅

Peso molecular: 449.63

Ref: ST-EA-CP-U1019