CAS 6610-42-0

Benzyloxicarbonil-L-glutaminilglicina

Descrição:

Benzyloxicarbonil-L-glutaminilglicina, comumente referido como Z-Glu-Gly, é um derivado de peptídeo sintético caracterizado pela presença de um grupo protetor benzyloxycarbonyl (Z) no resíduo de glutamina. Este composto é tipicamente utilizado na síntese de peptídeos e na pesquisa devido à sua estabilidade e capacidade de proteger o grupo amino durante reações químicas. A estrutura consiste em uma glutamina (Glu) e glicina (Gly) ligadas por uma ligação peptídica, tornando-se um dipeptídeo. O grupo Z aumenta a solubilidade e reatividade da molécula, facilitando seu uso em várias aplicações bioquímicas. É frequentemente empregado na síntese de peptídeos e proteínas mais complexas, servindo como um bloco de construção no desenvolvimento de produtos farmacêuticos e bioquímicos. O composto é geralmente estável sob condições laboratoriais padrão, mas pode ser sensível a ácidos ou bases fortes, o que pode levar à hidrólise da ligação peptídica. Assim como muitos derivados de peptídeos, é importante manuseá-lo com cuidado, seguindo os protocolos de segurança apropriados.

Fórmula: C₁₅H₁₉N₃O₆

InChI: InChI=1S/C15H19N3O6/c16-12(19)7-6-11(14(22)17-8-13(20)21)18-15(23)24-9-10-4-2-1-3-5-10/h1-5,11H,6-9H2,(H2,16,19)(H,17,22)(H,18,23)(H,20,21)/t11-/m0/s1

Chave InChI: InChIKey=SOUXAAOTONMPRY-NSHDSACASA-N

SMILES: [C@H](C(NCC(O)=O)=O)(NC(OCC1=CC=CC=C1)=O)CCC(N)=O

Sinónimos:

• 2-[[(2S)-5-Amino-5-oxo-2-(phenylmethoxycarbonylamino)pentanoyl]amino]acetic acid
• Benzyloxycarbonyl-<span class="text-smallcaps">L</span>-glutaminylglycine
• Carbobenzoxy-<span class="text-smallcaps">L</span>-glutaminylglycine
• Glycine, N-(N²-carboxy-<span class="text-smallcaps">L</span>-glutaminyl)-, N-benzyl ester
• Glycine, N-(N²-carboxy-<span class="text-smallcaps">L</span>-glutaminyl)-, N²-benzyl ester
• Glycine, N-[N²-[(phenylmethoxy)carbonyl]-<span class="text-smallcaps">L</span>-glutaminyl]-
• Glycine, N²-[(phenylmethoxy)carbonyl]-<span class="text-smallcaps">L</span>-glutaminyl-
• N-(Benzyloxycarbonyl)-<span class="text-smallcaps">L</span>-glutaminylglycine
• N²-[(Phenylmethoxy)carbonyl]-<span class="text-smallcaps">L</span>-glutaminylglycine
• N^α-(Benzyloxycarbonyl)-<span class="text-smallcaps">L</span>-glutaminylglycine
• NSC 186901
• N~2~-[(benzyloxy)carbonyl]glutaminylglycine
• Z-Gln-Gly-OH
• Glycine, N-(N2-carboxy-L-glutaminyl)-, N2-benzyl ester
• Glycine, N-[N2-[(phenylmethoxy)carbonyl]-L-glutaminyl]-
• Glycine, N2-[(phenylmethoxy)carbonyl]-L-glutaminyl-
• Glycine, N-(N2-carboxy-L-glutaminyl)-, N-benzyl ester

N-Benzyloxycarbonyl-L-glutaminylglycine, 98%

CAS: 6610-42-0

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Fórmula: C₁₅H₁₉N₃O₆

Pureza: 98%

Cor e Forma: White to pale cream, Powder

Peso molecular: 337.33

Ref: 02-H65088

Z-Gln-Gly-OH

CAS: 6610-42-0

Substrate for tissue transaminase. De Macédo et al. described a direct continuous spectrophotometric assay for transglutaminase (TGase) activity.

Fórmula: C₁₅H₁₉N₃O₆

Pureza: > 99%

Cor e Forma: White Powder

Peso molecular: 337.33

Ref: 01-4002246

Z-GLN-GLY-OH

CAS: 6610-42-0

Fórmula: C₁₅H₁₉N₃O₆

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 337.3279

Ref: IN-DA00FAC9

Z-GLN-GLY-OH

CAS: 6610-42-0

Z-GLN-GLY-OH

Pureza: 98%

Peso molecular: 337.33g/mol

Ref: 54-OR1015448

Z-Gln-Gly

CAS: 6610-42-0

Z-Gln-Gly is a protected dipeptide, which is commonly used as an intermediate in peptide synthesis. It is derived from the amino acids glutamine and glycine, with the N-terminal glutamine being protected by a benzyloxycarbonyl (Z or Cbz) group. This protective group is essential for preventing undesirable reactions at the amine site during peptide chain elongation.The primary mode of action for Z-Gln-Gly involves its use in solid-phase peptide synthesis, where the Z-group safeguards the amine functionality. This protection allows for selective reactions at other sites of the molecule until the final deprotection step, facilitating the sequential addition of amino acids.Z-Gln-Gly is used predominantly in research and development within biochemical and pharmaceutical laboratories. Its applications are critical in the synthesis of longer peptide chains and peptide-based drugs, where precision and control over the peptide structure are paramount for investigating biological processes and therapeutic functions.

Fórmula: C₁₅H₁₉N₃O₆

Pureza: Min. 95%

Peso molecular: 337.33 g/mol

Ref: 3D-SZQ-3190

Z-Gln-Gly-OH

CAS: 6610-42-0

Z-Gln-Gly-OH is a synthetic dipeptide, which is a modified amino acid sequence commonly used in biochemical applications. It consists of a carbobenzoxy-protected glutamine and a glycine residue. This compound originates from custom organic synthesis, derived through specific chemical protocols to introduce protective groups that block reactive sites on the amino acids. This controlled modification alters the peptide's stability and solubility.The mode of action involves the protection of active sites during complex syntheses, enabling the sequential construction of peptide chains without unintended reactions. This protection is critical in solid-phase peptide synthesis methodologies where precision and specificity of reactions are paramount. The Z-group (benzyloxycarbonyl) ensures the stability of glutamine under various chemical conditions, preventing side reactions that may compromise the integrity of peptide constructs.In research, Z-Gln-Gly-OH finds applications in the design of peptide-based inhibitors, structural studies, and the synthesis of longer chain peptides that mimic biologically relevant structures. The protection strategy allows scientists to develop and manipulate peptides with high fidelity, facilitating advancements in understanding protein functions and interactions in physiological contexts.

Fórmula: C₁₅H₁₉N₃O₆

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 337.33 g/mol

Ref: 3D-FG111459

(S)-2-(5-Amino-2-(((benzyloxy)carbonyl)amino)-5-oxopentanamido)acetic acid

CAS: 6610-42-0

Fórmula: C₁₅H₁₉N₃O₆

Pureza: 98%

Peso molecular: 337.332

Ref: 10-F222428