CAS 66592-87-8

Cefadroxila monohidratada

Descrição:

Cefadroxila monohidratada é um antibiótico semissintético pertencente à classe das cefalosporinas, utilizado principalmente para tratar infecções bacterianas. É caracterizado por sua atividade de amplo espectro contra bactérias Gram-positivas e Gram-negativas, tornando-o eficaz para várias infecções, incluindo aquelas da pele, trato respiratório e sistema urinário. A estrutura química do cefadroxilo inclui um anel beta-lactâmico, que é essencial para sua ação antibacteriana, pois inibe a síntese da parede celular bacteriana. Cefadroxila monohidratada aparece como um pó cristalino branco a off-white e é solúvel em água, o que facilita sua formulação em formas de dosagem oral. A forma monohidratada indica que contém uma molécula de água para cada molécula de cefadroxilo, influenciando sua estabilidade e solubilidade. Comumente administrado por via oral, o cefadroxilo é geralmente bem tolerado, embora os efeitos colaterais potenciais possam incluir distúrbios gastrointestinais e reações alérgicas. Sua farmacocinética envolve absorção no trato gastrointestinal, com concentrações plasmáticas máximas ocorrendo dentro de algumas horas após a administração.

Fórmula: C₁₆H₁₇N₃O₅S

InChI: InChI=1/C16H17N3O5S.H2O/c1-7-6-25-15-11(14(22)19(15)12(7)16(23)24)18-13(21)10(17)8-2-4-9(20)5-3-8;/h2-5,10-11,15,20H,6,17H2,1H3,(H,18,21)(H,23,24);1H2/t10?,11-,15-;/m1./s1

Chave InChI: InChIKey=NBFNMSULHIODTC-CYJZLJNKSA-N

SMILES: C(O)(=O)C=1N2[C@@]([C@H](NC([C@H](N)C3=CC=C(O)C=C3)=O)C2=O)(SCC1C)[H].O

Sinónimos:

• (6R,7R)-7-{[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino}-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid hydrate (1:1)
• (6R,7R)-7-{[amino(4-hydroxyphenyl)acetyl]amino}-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• (6R,7R)-7-{[amino(4-hydroxyphenyl)acetyl]amino}-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid hydrate
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-((amino(4-hydroxyphenyl)acetyl)amino)-3-methyl-8-oxo, monohydrate, (6R-(6alpha,7beta(R*)))-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino]-3-methyl-8-oxo-, hydrate (1:1), (6R,7R)-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2R)-amino(4-hydroxyphenyl)acetyl]amino]-3-methyl-8-oxo-, monohydrate, (6R,7R)-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[amino(4-hydroxyphenyl)acetyl]amino]-3-methyl-8-oxo-, monohydrate, [6R-[6α,7β(R*)]]-
• 7-{[Amino(4-Hydroxyphenyl)Acetyl]Amino}-3-Methyl-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid
• Cefadroxil Micronised Powder
• Duricef
• Ultracef
• Cefadroxil monohydrate
• (6R,7R)-7-[[(2R)-Amino-(4-hydroxyphenyl)acetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid Monohydrate
• CEFADROXIL
• Cefradroxil
• AMOXYCILLIN
• CEFADDROXIL
• Cefa-Drops
• Cefadroxil hydrate
• (6R,7R)-7-[(R)-2-AMINO-2-(4-HYDROXY-PHENYL)-ACETYLAMINO]-3-METHYL-8-OXO-5-THIA-1-AZA-BICYCLO[4.2.0]OCT-2-ENE-2-CARBOXYLIC ACID
• CEFAMOX
• MJF-11567-3
• monohydrate,(6r-(6-alpha,7-beta(r*)))-l)acetyl)amino)-3-methyl-8-oxo
• (6R,7R)-7-[[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid hydrate
• Baxan
• 7-[[2-Amino-2-(4-hydroxyphenyl)acetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• 5-Thia-1-azabicyclo4.2.0oct-2-ene-2-carboxylic acid, 7-(2R)-amino(4-hydroxyphenyl)acetylamino-3-methyl-8-oxo-, monohydrate, (6R,7R)-
• p-Hydroxycephalexine Monohydrate
• Duracef
• 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-((amino(4-hydroxyphenyl)acetyl) amino)-3-methyl-8-oxo-, monohydrate, (6R-(6-alpha,7-beta(R*)))

Cefadroxil Monohydrate

CAS: 66592-87-8

Cor e Forma: Neat

Ref: 61-FOR0972.00

Cefadroxil

CAS: 66592-87-8

Cefadroxil

Fórmula: C₁₆H₁₇N₃O₅S

Pureza: 93.8%

Cor e Forma: White

Peso molecular: 363.08889

Ref: 47-784

CEFADROXIL CRS

CAS: 66592-87-8

CEFADROXIL CRS

Ref: 41-C0650000

Cefadroxil

CAS: 66592-87-8

Antibiotics nesoi

Fórmula: C₁₆H₁₇N₃O₅S·H₂O

Cor e Forma: White Light Yellow Powder

Peso molecular: 363.08889

Ref: 45-1097104

5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,7-[[(2R)-amino(4-hydroxyphenyl)acetyl]amino]-3-methyl-8-oxo-,monohydrate, (6R,7R)-

CAS: 66592-87-8

Fórmula: C₁₆H₁₉N₃O₆S

Pureza: 97%

Cor e Forma: Solid

Peso molecular: 381.4036

Ref: IN-DA01CCHV

Cefadroxil monohydrate

CAS: 66592-87-8

Fórmula: C₁₆H₁₇N₃O₅S·H₂O

Pureza: 98.0 - 102.0 %

Cor e Forma: White or off-white powder

Peso molecular: 381.40

Ref: 7W-GA2276

(6R,7R)-7-((R)-2-Amino-2-(4-Hydroxyphenyl)Acetamido)-3-Methyl-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid Hydrate

CAS: 66592-87-8

(6R,7R)-7-((R)-2-Amino-2-(4-Hydroxyphenyl)Acetamido)-3-Methyl-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid Hydrate

Pureza: 97%

Peso molecular: 381.4g/mol

Ref: 54-OR1028850

Cefadroxil Monohydrate

Produto Controlado

CAS: 50370-12-2, 66592-87-8

Fórmula: C₁₆H₁₇N₃O₅S

Cor e Forma: Neat

Peso molecular: 363.39

Ref: 86-MM0972.00

Cefadroxil Monohydrate

CAS: 66592-87-8

Fórmula: C₁₆H₁₇N₃O₅S·H₂O

Pureza: >98.0%(T)(HPLC)

Cor e Forma: White to Light yellow powder to crystal

Peso molecular: 381.41

Ref: 3B-C3951

Cefadroxil Monohydrate

Produto Controlado

CAS: 66592-87-8

Applications Cefadroxil is a semi-synthetic cephalosporin antibiotic. Antibacterial.
References Buck, R.E., et al.: Antimicrob. Agents Chemother., 11, 324 (1977);

Fórmula: C₁₆H₁₇N₃O₅S·H₂O

Cor e Forma: White

Peso molecular: 381.40

Ref: TR-C235750

Cefadroxil monohydrate

CAS: 66592-87-8

Cefadroxil monohydrate is a hydrated form of cefadroxil with similar action and applications as cefadroxil.

Fórmula: C₁₆H₁₇N₃O₅S•H₂O

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 381.41 g/mol

Ref: 3D-AC19845

Cefadroxil Monohydrate (CFD), 95%

CAS: 66592-87-8

Fórmula: C₁₆H₁₇N₃O₅S·H₂O

Pureza: min. 95%

Cor e Forma: White to off - white, Crystalline powder

Peso molecular: 381.40

Ref: SR-15689

Cefadroxil monohydrate, Antibiotic for Culture Media Use Only

CAS: 66592-87-8

Cefadroxil is a broad-spectrum bactericidal antibiotic that belongs to the cephalosporin family. It is a semi-synthetic penicillin and inhibits bacterial cell wall synthesis through binding to one or more of the penicillin-binding proteins (PBPs). Cefadroxil monohydrate is used as an antibiotic for culture media and has been proven to be effective against methicillin-resistant Staphylococcus aureus (MRSA). In addition, the drug has been shown to have no significant effect on blood tests or microscopic studies.

Fórmula: C₁₆H₁₉N₃O₆S

Pureza: Min. 97.0 Area-%

Peso molecular: 381.40 g/mol

Ref: 3D-Q-200807

Cefadroxil (hydrate)

CAS: 66592-87-8

Cefadroxil is a first generation aminocephalosporin with good patient compliance, a long-acting therapeutic effect, high solubility and relatively broad spectrum of anti-bacterial activity. Cefadroxil is also a substrate of the intestinal peptide transporter PepT1, which is primarily responsible for the drug's uptake across the apical membrane of small intestine.

Fórmula: C₁₆H₁₉N₃O₆S

Cor e Forma: White Crystalline Solid

Peso molecular: 381.404

Ref: TM-T0366L