CAS 66803-19-8

Sulfato de micronomicina

Descrição:

Sulfato de micronomicina é um antibiótico aminoglicosídeo derivado de Micromonospora purpurea, usado principalmente por suas propriedades antibacterianas. Apresenta um amplo espectro de atividade contra várias bactérias Gram-negativas e algumas Gram-positivas, tornando-se eficaz no tratamento de infecções, especialmente aquelas causadas por cepas resistentes. O composto atua inibindo a síntese de proteínas bacterianas, que é crucial para o crescimento e replicação bacteriana. Sulfato de micronomicina é tipicamente administrado por injeção e é conhecido por sua toxicidade relativamente baixa em comparação com outros aminoglicosídeos, embora ainda possa apresentar riscos como nefrotoxicidade e ototoxicidade. A forma sulfato melhora sua solubilidade e estabilidade em solução, facilitando seu uso em ambientes clínicos. Assim como outros aminoglicosídeos, o monitoramento cuidadoso dos níveis do medicamento na corrente sanguínea é essencial para evitar efeitos adversos. No geral, Sulfato de micronomicina é um antibiótico valioso no arsenal terapêutico contra infecções bacterianas, especialmente em casos onde outros tratamentos podem falhar devido à resistência.

Fórmula: C₂₀H₄₃N₅O₁₁S

InChI: InChI=1/C20H41N5O7.H2O4S/c1-20(28)8-29-19(14(27)17(20)25-3)32-16-12(23)6-11(22)15(13(16)26)31-18-10(21)5-4-9(30-18)7-24-2;1-5(2,3)4/h9-19,24-28H,4-8,21-23H2,1-3H3;(H2,1,2,3,4)/t9-,10+,11-,12+,13-,14+,15+,16-,17+,18+,19+,20-;/m0./s1

Chave InChI: InChIKey=MQDGQSCLOYLSEK-SCFBDNQUSA-N

SMILES: O([C@@H]1[C@@H](O)[C@H](O[C@H]2O[C@H](CNC)CC[C@H]2N)[C@@H](N)C[C@H]1N)[C@@H]3[C@H](O)[C@@H](NC)[C@@](C)(O)CO3.S(=O)(=O)(O)O

Sinónimos:

• (1R,2S,3S,4R,6S)-4,6-diamino-3-{[3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyl]oxy}-2-hydroxycyclohexyl 2-amino-2,3,4,6-tetradeoxy-6-(methylamino)-alpha-D-erythro-hexopyranoside sulfate (1:1)
• <span class="text-smallcaps">D</smallcap>-Streptamine, O-2-amino-2,3,4,6-tetradeoxy-6-(methylamino)-α-<smallcap>D</smallcap>-erythro-hexopyranosyl-(1→4)-O-[3-deoxy-4-C-methyl-3-(methylamino)-β-<smallcap>L</span>-arabinopyranosyl-(1→6)]-2-deoxy-, sulfate (1:?)
• <span class="text-smallcaps">D</smallcap>-Streptamine, O-2-amino-2,3,4,6-tetradeoxy-6-(methylamino)-α-<smallcap>D</smallcap>-erythro-hexopyranosyl-(1→4)-O-[3-deoxy-4-C-methyl-3-(methylamino)-β-<smallcap>L</span>-arabinopyranosyl-(1→6)]-2-deoxy-, sulfate (salt)
• Micronomycin sulfate
• Streptamine, O-2-amino-2,3,4,6-tetradeoxy-6-(methylamino)-alpha-D-erythro-hexopyranosyl-(1-4)-O-(3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyl-(1-6))-2-deoxy-, sulfate, D-
• Micronomicin sulfate
• D-Streptamine, O-2-amino-2,3,4,6-tetradeoxy-6-(methylamino)-α-D-erythro-hexopyranosyl-(1→4)-O-[3-deoxy-4-C-methyl-3-(methylamino)-β-L-arabinopyranosyl-(1→6)]-2-deoxy-, sulfate (1:?)
• D-Streptamine, O-2-amino-2,3,4,6-tetradeoxy-6-(methylamino)-α-D-erythro-hexopyranosyl-(1→4)-O-[3-deoxy-4-C-methyl-3-(methylamino)-β-L-arabinopyranosyl-(1→6)]-2-deoxy-, sulfate (salt)
• yranosyl-(1-4)-o-(3-deoxy-4-c-methyl-3-(methylamino)-beta-l-arabinopyranosyl-(
• MICRONOMICIN SULFATE USP/EP/BP
• streptamine,o-2-amino-2,3,4,6-tetradeoxy-6-(methylamino)-alpha-d-erythro-hexop
• sulfate,d-1-6))-2-deoxy
• (2R,3R,4R,5R)-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-[(2R,3R,6S)-3-amino-6-(methylaminomethyl)oxan-2-yl]oxy-2-hydroxycyclohexyl]oxy-5-methyl-4-(methylamino)oxane-3,5-diol,sulfuric acid
• D-Streptamine, O-2-amino-2,3,4,6-tetradeoxy-6-(methylamino)-a-D-erythro-hexopyranosyl-(14)-O-[3-deoxy-4-C-methyl-3-(methylamino)-b-L-arabinopyranosyl-(16)]-2-deoxy-, sulfate (salt) (9CI)
• 6'-N-METHYLGENTAMICIN C1A HEMIPENTASULFATE
• Micronomicin sulfate JAS1998
• Micronomicin Sulfate CAS: 66803-19-8

Micronomicin sulfate, 590 ^mg/mg

CAS: 66803-19-8

An aminoglycoside antibiotic commonly used against Gram-negative bacteria This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU

Fórmula: C₂₀H₄₁N₅O₇•H₂SO₄

Cor e Forma: White to off-white, Powder

Peso molecular: 561.65

Ref: 02-J66072

(2R,3R,4R,5R)-2-(((1S,2S,3R,4S,6R)-4,6-Diamino-3-(((2R,3R,6S)-3-amino-6-((methylamino)methyl)tetrahydro-2H-pyran-2-yl)oxy)-2-hydroxycyclohexyl)oxy)-5-methyl-4-(methylamino)tetrahydro-2H-pyran-3,5-diol sulfate

CAS: 66803-19-8

Fórmula: C₂₀H₄₃N₅O₁₁S

Pureza: 95%

Cor e Forma: Solid

Peso molecular: 561.6473

Ref: IN-DA00FA9E

Micronomicin sulfate

CAS: 66803-19-8

Micronomicin sulfate

Pureza: ≥95%

Ref: 54-BUP20960

Micronomicin sulfate

CAS: 66803-19-8

Micronomicin sulfate (Gentamicin C2b sulfate) is an aminoglycoside antibiotic with antimicrobial activity that inhibits neuraminidase N1 of influenza A virus.

Fórmula: C₂₀H₄₁N₅O₇xH₂O₄S

Cor e Forma: Solid

Peso molecular: #VALUE!

Ref: TM-T41294

Micronomicin Sulfate (~80%)

Produto Controlado

CAS: 66803-19-8

Applications Micronomicin Sulfate is an aminoglycoside antibiotic with neuromuscular blocking activity.
References Matsukawa, S., et al.: Tohoku J. Exp. Med., 181, 471 (1997)

Fórmula: C₂₀H₄₁N₅O₇·H₂O₄S

Pureza: ~80%

Cor e Forma: Neat

Peso molecular: 561.65

Ref: TR-M342900

Micronomicin Sulfate

CAS: 66803-19-8

Micronomicin sulfate is an antimicrobial agent that belongs to the group of sulfonamides. It has been used in clinical studies for the treatment of chronic bronchitis. Micronomicin sulfate inhibits bacterial growth by binding to fatty acid synthesis enzymes and inhibiting membrane function. This drug also has a broad-spectrum antimicrobial action, which includes activity against gram-positive bacteria, gram-negative bacteria, and fungi. Micronomicin sulfate is not active against mycobacteria and is used in combination with other antibiotics for the treatment of infections caused by these bacteria. Micronomicin sulfate can be administered intravenously as an injection solution or orally as a tablet or syrup. It can also be given rectally as an enema solution or suppository. A formulation for intramuscular injection is also available but this formulation should not be injected into a vein or artery.

Fórmula: C₂₀H₄₁N₅O₇xH₂SO₄

Pureza: Min. 590 Ug/Mg

Cor e Forma: Powder

Peso molecular: 463.57 g/mol

Ref: 3D-RCA80319