CAS 68-89-3

Dipirona

Descrição:

Dipirona, também conhecido como metamizol, é um analgésico e antipirético não opioide comumente utilizado para alívio da dor e redução da febre. É classificado como um derivado de pirazolona e é conhecido por suas potentes propriedades analgésicas. Dipirona é tipicamente administrado em sua forma de sal sódico, o que melhora sua solubilidade em água. O composto é caracterizado por sua capacidade de inibir a síntese de prostaglandinas, reduzindo assim a dor e a inflamação. É frequentemente utilizado em ambientes clínicos para o manejo da dor severa, particularmente quando outros analgésicos são ineficazes. No entanto, Dipirona tem sido associado a efeitos colaterais graves, incluindo agranulocitose, uma diminuição potencialmente fatal na contagem de glóbulos brancos, o que levou ao seu uso restrito em alguns países. A substância é geralmente bem absorvida quando administrada por via oral ou intravenosa, e seus efeitos podem ser rápidos, tornando-a uma opção valiosa em cenários de dor aguda. Apesar de sua eficácia, os profissionais de saúde devem pesar os benefícios em relação aos riscos ao considerar Dipirona para o tratamento do paciente.

Fórmula: C₁₃H₁₆N₃NaO₄S

InChI: InChI=1/C13H19N3O4S.Na/c1-10-12(14(2)9-21(18,19)20)13(17)16(15(10)3)11-7-5-4-6-8-11;/h4-8,10,12H,9H2,1-3H3,(H,18,19,20);/q;+1/p-1/rC13H18N3NaO4S/c1-10-12(14(2)9-22(19,20)21-17)13(18)16(15(10)3)11-7-5-4-6-8-11/h4-8,10,12H,9H2,1-3H3

Chave InChI: InChIKey=CEOUXRNZHGKECQ-UHFFFAOYSA-N

SMILES: O=C1N(N(C)C(C)=C1N(CS(=O)(=O)O)C)C2=CC=CC=C2.[Na]

Sinónimos:

• Algocalmin
• Algopyrin
• Amoloid HV
• Amoloid LV
• Anador
• Analgin
• Analgin DAB10
• Analgine
• Andolor
• Arpf
• Collatex A/RE
• Collatex Arm Extra
• CollatexA/RE Extra
• Conmel
• Diprofarn
• Dipyrone,hydrate
• Duckammon
• E 403
• Gifaril
• Kimica Algin NH
• Kimitsu Algin NH
• Lisador
• Manutex PC-MV
• Metamizol
• Metamizole
• Metamizole Sodium
• Metamizole sodium salt
• Metapyrin
• Methamizole sodium
• Methampyrone
• Methanesulfonic acid, (antipyrinylmethylamino)-, sodium salt
• Methanesulfonic acid, 1-[(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino]-, sodium salt (1:1)
• Methanesulfonic acid, [(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino]-, sodium salt
• Methylmelubrin
• Metilon
• Narone
• Natrium-[(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino]methansulfonat
• Neo-melubrine
• Noramidopyrine methanesulfonate sodium
• Noramidopyrine methanesulfonate sodium salt
• Noraminophenazone methanesulfonate sodium salt
• Noraminophenazone sodium mesylate
• Novalgetol
• Novalgin
• Novamidazophen
• Novaminophenazone
• Novaminsulfone
• Novaminsulfone sodium
• Novaminsulfonium
• Novaminsulfonum
• Noveltex
• Optalgin
• Pharmalgine
• Protamon S
• Pyralgine
• Pyretin
• Pyretin (pharmaceutical)
• Restriva
• Sodium ((2,3-Dihydro-1,5-Dimethyl-3-Oxo-2-Phenyl-1H-Pyrazol-4-Yl)Methylamino)Methanesulfonate
• Sodium (antipyrinylmethylamino)methanesulfonate
• Sodium 1-phenyl-2,3-dimethyl-5-pyrazolone-4-methylaminomethanesulfonate
• Sodium [(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino]methanesulphonate
• Sodium metamizole
• Sodium noramidopyrine methanesulfonate
• Sodium novaminsulfonate
• Sulpin
• Sulpyrin
• Sulpyrine
• [(1,5-Dimethyl-3-Oxo-2-Phenyl-Pyrazolidin-4-Yl)-Methyl-Amino]Methylsulfonyloxy Sodium
• [(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)(methyl)amino]methanesulfonate
• [(2,3-Dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino]methanesulfonic acid sodium salt
• [(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazole-4-yl)methylamino]methanesulfonate de sodium
• [(2-fenil-2,3-dihidro-1,5-dimetil-3-oxo-1H-pirazol-4-il)metilamino]metanosulfonato de sodio
• sodium [(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)(methyl)amino]methanesulfonate
• sodium [(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)(methyl)amino]methanesulfonate hydrate (1:1:1)
• Dipyrone
• BENZALAGEN
• (antipyrinylmethylamino)-methanesulfonicacimonosodiumsalt
• SODIUM [(1,5-DIMETHYL-3-OXO-2-PHENYL-PYRAZOL-4-YL)-METHYL-AMINO]METHANESULFONATE
• 4-methylamino-1,5-dimethyl-2-phenyl-3-pyrazolonesodiummethanesulfonate
• (antipyrinylmethylamino)methanesulfonicacidsodiumsalt
• 1-phenyl-2,3-dimethylpyrazolone-(5)-4-methylaminomethanesulfonicacidsodium
• dipyron
• LABOTEST-BB LT00771955
• (antipyrinylmethylamino)-methanesulfonicacisodiumsalt
• DIPYRONE SODIUM
• 1-phenyl-2,3-dimethyl-5-pyrazolone-4-methylaminomethanesulfonatesodium
• METAMIZOL SODIUM
• SODIUM DIPYRONE

Metamizole Sodium Salt

CAS: 68-89-3

Fórmula: C₁₃H₁₆N₃NaO₄S

Pureza: >98.0%(T)(HPLC)

Cor e Forma: White to Almost white powder to crystal

Peso molecular: 333.34

Ref: 3B-M3060

Dipyrone

CAS: 68-89-3

Fórmula: C₁₃H₁₇N₃NaO₄S

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 334.3465

Ref: IN-DA006FYJ

Metamizole sodium

CAS: 68-89-3

Metamizole sodium (Analgin) is a drug that has analgesic, anti-inflammatory, and antipyretic properties. It is the sodium sulfonate of AMINOPYRINE.

Fórmula: C₁₃H₁₆N₃NaO₄S

Pureza: 99.52%

Cor e Forma: White Or Almost White Crystal Powder

Peso molecular: 333.34

Ref: TM-T1191L

Metamizole Sodium Salt (Dipyrone)

CAS: 68-89-3

Fórmula: C₁₃H₁₆N₃O₄S·Na

Cor e Forma: White To Off-White Solid

Peso molecular: 310.35 22.99

Ref: 4Z-M-531

Dipyrone

CAS: 68-89-3

Dipyrone

Pureza: 98%

Peso molecular: 333.34g/mol

Ref: 54-OR1029314

Metamizole sodium

CAS: 68-89-3

Metamizole sodium

Pureza: ≥98%

Peso molecular: 333.34g/mol

Ref: 54-BUP10835

Metamizol sodium

Produto Controlado

CAS: 68-89-3

Fórmula: C₁₃H₁₆N₃O₄S·Na

Cor e Forma: White

Peso molecular: 333.34

Ref: 04-C14942000

Dipyrone

Produto Controlado

CAS: 68-89-3

Applications Dipyrone is a non-steroidal anti-inflammatory drug that, when coadministered with morphine, potentiates its antinociceptive action and delays the development of tolerance. Dipyrone is a relatively selective inhibitor of cyclooxygenase-3 (COX-3), with lower activity against COX-1 and no activity against COX-2. Dipyrone blocks PGE2-induced hyperalgesia in several models. Neuroprotective & Neuroresearch Product.
References Reith, J., et al.: Lancet, 347, 422 (1996), Grau, A., et al.: J. Neurol. Sci., 171, 115 (1999), Schwarz, S., et al.: Neurology, 2000, 54, 354 (2000), Greer, D., et al.: Stroke, 39, 3029 (2008),

Fórmula: C₁₃H₁₆N₃O₄S·Na

Cor e Forma: Neat

Peso molecular: 333.34

Ref: TR-D492860

Dipyrone-d3

Produto Controlado

CAS: 68-89-3

Stability Hygroscopic
Applications Labelled Dipyrone. Dipyrone is a non-steroidal anti-inflammatory drug that, when coadministered with morphine, potentiates its antinociceptive action and delays the development of tolerance. Dipyrone is a relatively selective inhibitor of cyclooxygenase-3 (COX-3), with lower activity against COX-1 and no activity against COX-2. Dipyrone blocks PGE2-induced hyperalgesia in several models.
References Reith, J. et al.: Lancet, 347, 422 (1996); Grau, A. et al.: J. Neurol. Sci., 171, 115 (1999); Schwarz, S. et al.: Neurology, 2000, 54, 354 (2000); Greer, D. et al.: Stroke, 39, 3029 (2008);

Fórmula: C₁₃H₁₃D₃N₃NaO₄S

Cor e Forma: Off-White

Peso molecular: 336.36

Ref: TR-D492862

Dipyrone

CAS: 68-89-3

Dipyrone is an anti-inflammatory and analgesic drug that belongs to the group of non-steroidal anti-inflammatory drugs. It has been shown to inhibit the production of prostaglandins, which are involved in inflammation, by inhibiting cyclooxygenase. The polymerase chain reaction (PCR) method is a biochemical technique used to amplify a segment of DNA, typically for use as a genetic marker or for cloning a particular gene. A PCR assay can be used to detect the presence of bacterial DNA in a sample. Dipyrone has been shown to possess chemiluminescence activity, which is indicative of its ability to bind with DNA. This binding inhibits transcription and replication and may be responsible for the toxic effects on epidermal cells observed in animal studies. Dipyrone also has been shown to have anti-inflammatory activities through its inhibition of cyclooxygenase and its ability to inhibit neutrophil migration and function.

Fórmula: C₁₃H₁₆N₃NaO₄S

Pureza: Min. 95%

Cor e Forma: White Solid

Peso molecular: 333.34 g/mol

Ref: 3D-FD22539

Dipyrone Sodium Salt

CAS: 68-89-3

Fórmula: C₁₃H₁₆N₃O₄SNa

Peso molecular: 310.3 : 23.0

Ref: ST-EA-CP-A231001