CAS 68767-14-6

Loxoprofeno

Descrição:

Loxoprofeno é um medicamento anti-inflamatório não esteroidal (AINE) usado principalmente por suas propriedades analgésicas e anti-inflamatórias. É comumente empregado no tratamento da dor e da inflamação associadas a condições como artrite, dor muscular e desconforto pós-operatório. Loxoprofeno funciona inibindo as enzimas ciclooxigenases (COX), que desempenham um papel crucial na síntese de prostaglandinas, compostos que mediam a inflamação e a dor. A substância é caracterizada por seu início de ação relativamente rápido e frequentemente é formulada em várias formas de dosagem, incluindo comprimidos e aplicações tópicas. Loxoprofeno é conhecido por seu perfil de segurança gastrointestinal favorável em comparação com outros AINEs, tornando-se uma escolha preferida em certos cenários clínicos. No entanto, como todos os medicamentos, pode ter efeitos colaterais, incluindo distúrbios gastrointestinais, riscos cardiovasculares e potenciais interações com outros medicamentos. Sua estrutura química inclui um derivado do ácido propiónico, contribuindo para sua atividade farmacológica. Assim como qualquer medicamento, é essencial usar Loxoprofeno sob supervisão médica para garantir segurança e eficácia.

Fórmula: C₁₅H₁₈O₃

InChI: InChI=1S/C15H18O3/c1-10(15(17)18)12-7-5-11(6-8-12)9-13-3-2-4-14(13)16/h5-8,10,13H,2-4,9H2,1H3,(H,17,18)

Chave InChI: InChIKey=YMBXTVYHTMGZDW-UHFFFAOYSA-N

SMILES: C(C1=CC=C(C(C(O)=O)C)C=C1)C2C(=O)CCC2

Sinónimos:

• 2-[4-(2-Oxo-Cyclopentylmethyl)-Phenyl]-Propionic Acid
• 2-[4-[(2-Oxocyclopentan-1-Yl)Methyl]Phenyl]Propionic Acid
• 2-[4-[(2-Oxocyclopentyl)methyl]phenyl]propionic acid
• 2-{4-[(2-Oxocyclopentyl)Methyl]Phenyl}Propanoic Acid
• A-Methyl-4-[(2-Oxocyclopentyl)Methyl]Benzeneacetic Acid
• Alpha-Methyl-4-[(2-Oxocyclopentyl)Methyl]Benzeneacetic Acid
• Benzeneacetic acid, α-methyl-4-[(2-oxocyclopentyl)methyl]-
• Ioxoprofen
• Koloxo
• Loxoprofen Acid
• ��-Methyl-4-[(2-Oxocyclopentyl)Methyl]Benzeneacetic Acid

Loxoprofen

CAS: 68767-14-6

Fórmula: C₁₅H₁₈O₃

Pureza: >97.0%(T)(HPLC)

Cor e Forma: White to Light yellow powder to crystal

Peso molecular: 246.31

Ref: 3B-L0244

Loxoprofen

CAS: 68767-14-6

Loxoprofen (Koloxo) is an anti-inflammatory non-steroidal medicine.

Fórmula: C₁₅H₁₈O₃

Pureza: 98.59%

Cor e Forma: White To Yellowish Crystalline Powder

Peso molecular: 246.3

Ref: TM-T0463

Loxoprofen

CAS: 68767-14-6

Fórmula: C₁₅H₁₈O₃

Pureza: 97%

Cor e Forma: Solid

Peso molecular: 246.3016

Ref: IN-DA003RD6

Loxoprofen

CAS: 68767-14-6

Fórmula: C₁₅H₁₈O₃

Pureza: ≥ 97.0%

Cor e Forma: White to faint yellow crystalline powder

Peso molecular: 246.30

Ref: 7W-GP1810

Loxoprofen

CAS: 68767-14-6

Loxoprofen

Pureza: ≥98%

Peso molecular: 246.3g/mol

Ref: 54-BUP15038

Loxoprofen

CAS: 68767-14-6

Loxoprofen

Pureza: 98%

Peso molecular: 246.3g/mol

Ref: 54-OR1030277

Loxoprofen

CAS: 68767-14-6

Fórmula: C₁₅H₁₈O₃

Cor e Forma: Off-White Solid

Peso molecular: 246.31

Ref: 4Z-L-891

Loxoprofen Impurity 1 and Loxoprofen Impurity 50

CAS: 68767-14-6

Fórmula: C₁₈H₂₄O₅

Peso molecular: 320.39

Ref: 4Z-L-8978

Loxoprofen-d4

CAS: 68767-14-6

Fórmula: C₁₅H₁₄D₄O₃

Cor e Forma: White To Off-White Solid

Peso molecular: 250.33

Ref: 4Z-L-8921

Loxoprofen Sodium Salt Dihydrate

CAS: 226721-96-6, 68767-14-6, 80382-23-6

Fórmula: C₁₅H₁₇NaO₃·2H₂O

Pureza: >98.0%(T)(HPLC)

Cor e Forma: White to Almost white powder to crystal

Peso molecular: 304.32

Ref: 3B-L0252

Loxoprofen-d6

CAS: 68767-14-6

Fórmula: C₁₅H₁₂D₆O₃

Peso molecular: 252.35

Ref: 4Z-L-897

Loxoprofen RS

CAS: 68767-14-6

Cor e Forma: White Solid Crystalline Powder

Ref: 2K-1188000021

Loxoprofen

Produto Controlado

CAS: 68767-14-6

Applications Loxoprofen is a non-selective nonsteroidal anti-inflammatory drug (NSAID) that has been effective in reducing atherosclerosis in mice by reducing inflammation. Loxoprofen becomes active after metabolism in the body and inhibits the activation of cyclooxygenase.
References Masahide H. et al.: J Clin Biochem Nutr., 47, 138 (2010); Noguchi, M. et al.: Biolog. Pharmac. Bull., 28, 2075 (2005); Hyun, J. et al.: Arch. Pharm. Res., 24, 541 (2001);

Fórmula: C₁₅H₁₈O₃

Cor e Forma: White To Off-White

Peso molecular: 246.30

Ref: TR-L472905

Loxoprofen-d3

Produto Controlado

CAS: 68767-14-6

Applications Loxoprofen-d3, is the labeled analogue of Loxoprofen (L472905), which is non-selective nonsteroidal anti-inflammatory drug (NSAID) that has been effective in reducing atherosclerosis in mice by reducing inflammation.
References Masahide H. et al.: J Clin Biochem Nutr., 47, 138 (2010); Noguchi, M. et al.: Biolog. Pharmac. Bull., 28, 2075 (2005); Hyun, J. et al.: Arch. Pharm. Res., 24, 541 (2001);

Fórmula: C₁₅H₁₅D₃O₃

Cor e Forma: Neat

Peso molecular: 249.32

Ref: TR-L472907

Loxoprofen (low-melting polymorph)

CAS: 68767-14-6

Loxoprofen is a non-steroidal anti-inflammatory drug that belongs to the class of drugs called pyrazoles. It is used in the treatment of inflammation and pain caused by arthritis, osteoarthritis, gout, menstrual pain, and dental pain. Loxoprofen binds to cyclooxygenase (COX) enzymes, thereby inhibiting prostaglandin synthesis. The COX enzymes are necessary for the production of prostaglandins that lead to inflammation and pain. Loxoprofen also inhibits bacterial translocation by binding to bacterial lipopolysaccharides on the cell surface and preventing their interaction with immune cells. Loxoprofen has been shown to inhibit colony stimulating factor (CSF) activity in vitro assays by disrupting CSF-1 binding to its receptor erythropoietin receptor or CD11b/CD18 integrin receptors on monocytes or neutrophils. This means that it will not stimulate the

Fórmula: C₁₅H₁₈O₃

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 246.3 g/mol

Ref: 3D-FL172228

Loxoprofen (high-melting polymorph)

CAS: 68767-14-6

Loxoprofen is a nonsteroidal anti-inflammatory drug that belongs to the group of drugs called NSAIDs. It has potent inhibitory activity against growth factor, which is important for the promotion of inflammation and tissue damage in diseases such as rheumatoid arthritis. Loxoprofen has been shown to have strong inhibitory effects on bacterial translocation in mice with colitis, which may be related to its ability to decrease the expression of endogenous substances through inhibition of colony-stimulating factor. Loxoprofen also has a high solubility in water (2g/L) and is soluble in biocompatible polymers such as polyvinylpyrrolidone.

Fórmula: C₁₅H₁₈O₃

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 246.31 g/mol

Ref: 3D-FL172231

Loxoprofen (high-melting polymorph)

CAS: 68767-14-6

Loxoprofen is a high-melting polymorph of loxoprofen, which is a nonsteroidal anti-inflammatory drug. Loxoprofen is used for the relief of pain and inflammation in patients with rheumatoid arthritis and osteoarthritis. It has been shown to be useful as an intermediate in the synthesis of other compounds, such as pharmaceuticals, pesticides, and dyes. Loxoprofen has also been found to be a useful building block in organic synthesis reactions that require high quality reagents.

Fórmula: C₁₅H₁₈O₃

Pureza: Min. 98.5 Area-%

Peso molecular: 246.31 g/mol

Ref: 3D-Q-201324

2-(4-((2-Oxocyclopentyl)methyl)phenyl)propanoic acid

CAS: 68767-14-6

Fórmula: C₁₅H₁₈O₃

Pureza: 95%

Cor e Forma: Solid

Peso molecular: 246.306

Ref: 10-F093438

Loxoprofen (low-melting polymorph)

CAS: 68767-14-6

Loxoprofen is a chemical intermediate that can be used to synthesize complex molecules. It has been shown to have many uses in the laboratory as a reaction component, reagent, or as a useful scaffold for research chemicals. Loxoprofen is also an effective building block for more complex compounds and can be used to synthesize speciality chemicals such as fine chemicals and pharmaceuticals. Loxoprofen is a white solid with low melting point that can be dissolved in organic solvents such as dichloromethane and chloroform.

Fórmula: C₁₅H₁₈O₃

Pureza: Min. 98.5 Area-%

Peso molecular: 246.31 g/mol

Ref: 3D-Q-300011