CAS 69-22-7

Citrato de cafeína

Descrição:

Citrato de cafeína é um composto químico que combina cafeína, um estimulante do sistema nervoso central, com ácido cítrico. É utilizado principalmente em ambientes médicos, particularmente para o tratamento da apneia em bebês prematuros, pois ajuda a estimular a respiração. Citrato de cafeína é um pó cristalino branco a off-white que é solúvel em água, o que facilita sua administração em ambientes clínicos. O composto exibe as propriedades estimulantes da cafeína, promovendo a alerta e reduzindo a fadiga. Sua farmacocinética envolve rápida absorção e metabolismo no fígado, levando a um aumento das concentrações plasmáticas de cafeína. O componente de citrato melhora a solubilidade e biodisponibilidade da cafeína, tornando-a mais eficaz para uso terapêutico. Citrato de cafeína é geralmente bem tolerado, mas os efeitos colaterais potenciais podem incluir aumento da frequência cardíaca, distúrbios gastrointestinais e nervosismo, particularmente em doses mais altas. Assim como qualquer medicamento, é importante usar Citrato de cafeína sob supervisão médica para garantir segurança e eficácia.

Fórmula: C₁₄H₁₈N₄O₉

InChI: InChI=1/C8H10N4O2.C6H8O7/c1-10-4-9-6-5(10)7(13)12(3)8(14)11(6)2;7-3(8)1-6(13,5(11)12)2-4(9)10/h4H,1-3H3;13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)

Chave InChI: InChIKey=RCQXSQPPHJPGOF-UHFFFAOYSA-N

SMILES: C(CC(O)=O)(CC(O)=O)(C(O)=O)O.O=C1C2=C(N(C)C(=O)N1C)N=CN2C

Sinónimos:

• 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, mixt. with 3,7-dihydro-1,3,7-trimethyl-1H-purine-2,6-dione
• 1H-Purine-2,6-dione, 3,7-dihydro-1,3,7-trimethyl-, mixt. contg.
• 1H-purine-2,6-dione, 3,7-dihydro-1,3,7-trimethyl-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1) (salt)
• Cafcit
• Caffeina citrate
• Caffeine Citrated
• Caffeine citrate
• Caffeine citrate (1:1)
• Caffeine, citrated [USAN]
• Cafnea
• Citrated caffein
• Citrated caffeine
• Citric acid, compd. with caffeine (1:1)
• Gencebok
• Peyona
• 1,3,7-Trimethyl-3,7-dihydro-1H-purine-2,6-dione 2-hydroxypropane-1,2,3-tricarboxylate (1:1)
• 1,3,7-TRIMETHYL-2,6-DIOXOPURINE CITRATE
• 1,3,7-Trimethyl-3,7-dihydro-purin-2,6-dion2-hydroxypropane-1,2,3-tricarboxylic acid,1,3,7-trimethyl
• thyl-1h-purine-2,6-dione
• 1,3,7-TRIMETHYLXANTHINE CITRATE
• Coffeinum-citrate
• citricacid,compd.withcaffeine(1:1)
• caffeinecitrate(1:1)
• CAFFEINE CITRATED GRANULAR
• caffeinacitrate
• Kaffein,Citrat
• COFFEINE CITRATE
• METHYLTHEOBROMINE CITRATE
• Caffeine Citrate USP
• Mixture with citric acid
• CAFFEINE,CITRATED,POWDER,PURIFIED
• GUARANINE CITRATE
• Caffeine, Citrated, Powder
• 2-HYDROXYPROPANE-1,2,3-TRICARBOXYLIC ACID,1,3,7-TRIMETHYLPURINE-2,6-DIONE
• citratedcaffein

Caffeine Citrate

Produto Controlado

CAS: 69-22-7

Fórmula: C₈H₁₀N₄O₂·C₆H₈O₇

Cor e Forma: Neat

Peso molecular: 386.31

Ref: 86-MM1851.00

Caffeine Citrate

CAS: 69-22-7

Fórmula: C₈H₁₀N₄O₂C₆H₈O₇

Peso molecular: 194.2 : 192.1

Ref: ST-EA-CP-C47008

Caffeine citrate

Produto Controlado

CAS: 69-22-7

Caffeine citrate is a low-dose caffeine product that has been shown to increase locomotor activity in rats. Caffeine citrate is an ester of caffeine and citric acid. It inhibits the enzyme that breaks down acetylcholine, which may lead to an increase in brain functions. Caffeine citrate is used as a treatment for apnea in pediatric patients, and it has also been shown to prevent bacterial translocation and reduce liver impairment caused by certain drugs. The therapeutic effect of caffeine citrate may be due to its ability to inhibit mitochondrial membrane potential, or its effects on basic proteins such as sodium citrate, or both.

Fórmula: C₈H₁₀N₄O₂·C₆H₈O₇

Cor e Forma: White Powder

Peso molecular: 386.31 g/mol

Ref: 3D-FC35311

Caffeine Citrate

CAS: 69-22-7

Applications Caffeine citrate (Cafcit) is a citrate salt of Caffeine, sometimes used in medical treatment, including short-term treatment of apnea of prematurity (lack of breathing in premature infants). Caffeine citrate functions in much the same capacity as does caffeine, but takes effect more quickly; its speed of dissociation is faster than that of Caffeine. Caffeine citrate is typically only used to treat severe migraines.
References Zubair, U.M., et al.: Anal. Profiles Drug Subs., 15, 71 (1986); Cherrah, Y., et al.: Biochem. Pharmacol., 37, 1311 (1988); Grillon, C., et al.: Clin. Neurophysiol., 114, 1557 (2003); Duangdao, D., et al.: Behav. Brain Res., 205, 1 (2009);

Fórmula: C₈H₁₀N₄O₂·C₆H₈O₇

Cor e Forma: White

Peso molecular: 386.31

Ref: TR-C080115

Caffeine Citrate

CAS: 69-22-7

Cor e Forma: Neat

Ref: 61-FOR1851.00