CAS 690655-41-5

NCX899

CAS: 690655-41-5

NCX899 is a novel drug that binds to the AT1 receptor and blocks the signaling of angiotensin II. It is an antagonist that has been shown to reduce blood pressure in animal models by preventing the binding of angiotensin II to its receptors in the carotid artery, thereby reducing vascular tone. The pharmacokinetics of NCX899 were studied in rats and dogs. The compound was found to be well absorbed after oral administration, with a tmax at 1-2 hours and a half-life of 3-4 hours. In rats, NCX899 showed inhibition of angiotensin converting enzyme (ACE) activity and tissue ACE levels. In addition, it was found to have high bioavailability, with only low plasma protein binding (less than 10%).

Fórmula: C₂₃H₃₃N₃O₈

Pureza: Min. 95%

Peso molecular: 479.5 g/mol

Ref: 3D-QCB65541

NCX899

CAS: 690655-41-5

NCX899 shows inhibitory activity against angiotensin-converting enzyme (ACE) activity.

Fórmula: C₂₃H₃₃N₃O₈

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 479.52

Ref: TM-T12198