CAS 69739-16-8

Cefodizima

Descrição:

Cefodizima é um antibiótico cefalosporínico de amplo espectro, classificado sob a terceira geração de cefalosporinas. É utilizado principalmente para o tratamento de várias infecções bacterianas devido à sua eficácia contra bactérias Gram-positivas e Gram-negativas. Cefodizima atua inibindo a síntese da parede celular bacteriana, levando à lise celular e morte. O composto é caracterizado por sua estabilidade contra certas beta-lactamases, o que aumenta sua eficácia contra cepas resistentes. Geralmente é administrado por injeção e possui um perfil farmacocinético favorável, permitindo uma penetração eficaz nos tecidos. As indicações comuns para Cefodizima incluem infecções do trato respiratório, infecções do trato urinário e infecções de pele. Assim como outros antibióticos, é essencial usar Cefodizima com cautela para minimizar o risco de desenvolvimento de resistência a antibióticos. Efeitos colaterais potenciais podem incluir reações alérgicas, distúrbios gastrointestinais e alterações nos parâmetros sanguíneos. No geral, Cefodizima representa uma opção valiosa no arsenal de terapias antimicrobianas, particularmente em ambientes onde a resistência a outros antibióticos é uma preocupação.

Fórmula: C₂₀H₂₀N₆O₇S₄

InChI: InChI=1/C20H20N6O7S4/c1-7-10(3-11(27)28)37-20(22-7)36-5-8-4-34-17-13(16(30)26(17)14(8)18(31)32)24-15(29)12(25-33-2)9-6-35-19(21)23-9/h6,13,17H,3-5H2,1-2H3,(H2,21,23)(H,24,29)(H,27,28)(H,31,32)/b25-12+/t13-,17-/m1/s1

Chave InChI: InChIKey=XDZKBRJLTGRPSS-BGZQYGJUSA-N

SMILES: C(O)(=O)C=1N2[C@@]([C@H](NC(/C(=N\OC)/C=3N=C(N)SC3)=O)C2=O)(SCC1CSC=4SC(CC(O)=O)=C(C)N4)[H]

Sinónimos:

• (6R,7R)-7-[[(2Z)-2-(2-Amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-3-[[[5-(carboxymethyl)-4-methyl-2-thiazolyl]thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• (6R,7R)-7-{[(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-({[5-(carboxymethyl)-4-methyl-1,3-thiazol-2-yl]sulfanyl}methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-({[5-(carboxymethyl)-4-methyl-1,3-thiazol-2-yl]sulfanyl}methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[[[5-(carboxymethyl)-4-methyl-2-thiazolyl]thio]methyl]-8-oxo-, [6R-[6α,7β(Z)]]-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[[[5-(carboxymethyl)-4-methyl-2-thiazolyl]thio]methyl]-8-oxo-, (6R,7R)-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-3-[[[5-(carboxymethyl)-4-methyl-2-thiazolyl]thio]methyl]-8-oxo-, (6R,7R)-
• 7-(((2-Amino-4-Thiazolyl)(Methoxyimino)Acetyl)Amino)-3-(((5-(Carboxymethyl)-4-Methyl-2-Thiazolyl)Thio)Methyl)-8-Oxo-5-Thia-1-Azabicyclo(4.2.0)Oct-2-Ene-2-Carboxylic Acid
• 7-(α-(Z)-Methoxyimino-α-(2-aminothiazol-4-yl)acetamido)-3-((5-carboxymethyl-4-methylthiazol-2-yl)thiomethyl)-3-cephem-4-carboxylic acid
• Cefodizime acid
• Cefodizime
• FIR-221

5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,7-[[(2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[[[5-(carboxymethyl)-4-methyl-2-thiazolyl]thio]methyl]-8-oxo-, (6R,7R)-

CAS: 69739-16-8

Fórmula: C₂₀H₂₀N₆O₇S₄

Pureza: 97%

Cor e Forma: Solid

Peso molecular: 584.6688

Ref: IN-DA01CCIC

Cefodizime

CAS: 69739-16-8

Cefodizime

Pureza: ≥98%

Peso molecular: 584.67g/mol

Ref: 54-BUP13742

Cefodizime

CAS: 69739-16-8

Fórmula: C₂₀H₂₀N₆O₇S₄

Peso molecular: 584.66

Ref: 4Z-C-313001

Cefodizime

CAS: 69739-16-8

Cefodizime: a new, well-tolerated cephalosporin antibiotic with immunomodulatory properties for serious respiratory and urinary infections.

Fórmula: C₂₀H₂₀N₆O₇S₄

Pureza: 99.62%

Cor e Forma: Solid

Peso molecular: 584.67

Ref: TM-T14922

Cefodizime

CAS: 69739-16-8

Applications Cefodizime is a third generation cephalosporin with a broad spectrum of antibacterial activity. Cefodizime maybe useful in the treatment of otitis media, sinusitis and gynaecological infections, and for the prophylaxis or treatment of surgical infections.
References Barradel, L.B. et al.: Drugs, 44, 800 (1992); Kasai, K. et al.: Jap. J. Antibiot., 37, 1306 (1984);

Fórmula: C₂₀H₂₀N₆O₇S₄

Cor e Forma: Neat

Peso molecular: 584.67

Ref: TR-C242865

Cefodizime

CAS: 69739-16-8

Cefodizime is a third-generation cephalosporin antibiotic, which is derived from the fungus Acremonium. It exerts its bactericidal effects by inhibiting bacterial cell wall synthesis. This action is achieved through binding to penicillin-binding proteins (PBPs), leading to the interruption of peptidoglycan cross-linking essential for the bacterial cell wall integrity. The breakdown of cell wall synthesis results in the lysis and death of the bacterial cell.

Pureza: Min. 95%

Ref: 3D-FC35157