CAS 7075-11-8

citosina B-D-arabinofuranosídeo*5'-monofosfato F

Descrição:

A citosina B-D-arabinofuranosídeo 5'-monofosfato F, comumente referida pelo seu número CAS 7075-11-8, é um análogo de nucleosídeo que desempenha um papel significativo em biologia molecular e farmacologia. Este composto é um derivado da citosina, uma das quatro principais nucleobases no DNA e RNA, e apresenta um grupo de açúcar arabinofuranosídeo. Sua estrutura inclui um grupo fosfato ligado na posição 5', que é crucial para sua função na síntese e metabolismo de ácidos nucleicos. A citosina B-D-arabinofuranosídeo 5'-monofosfato F é conhecida por suas potenciais propriedades antivirais e anticancerígenas, pois pode interferir na síntese de ácidos nucleicos em células que se dividem rapidamente. O composto é tipicamente utilizado em ambientes de pesquisa para estudar processos celulares e os mecanismos de ação de vários agentes terapêuticos. Sua solubilidade e estabilidade em sistemas biológicos fazem dele uma ferramenta valiosa no desenvolvimento de medicamentos baseados em nucleosídeos. No geral, este composto exemplifica a interseção da química e da biologia na busca por estratégias terapêuticas eficazes.

Fórmula: C₉H₁₄N₃O₈P

InChI: InChI=1/C9H14N3O8P/c10-5-1-2-12(9(15)11-5)8-7(14)6(13)4(20-8)3-19-21(16,17)18/h1-2,4,6-8,13-14H,3H2,(H2,10,11,15)(H2,16,17,18)/t4-,6-,7+,8-/m1/s1

Sinónimos:

• Ara-5'-CMP
• 1-beta-D-Arabinofuranosylcytosine 5'-monophosphate
• 1-beta-D-Arabinofuranosylcytosine 5'-phosphate
• 1beta-Arabino-furanosylcytosine-5'-monophosphoric acid, D-
• Arabinosylcytosine 5'-monophosphate
• Aracytidine 5'-monophosphate
• Aracytidine 5'-phosphate
• Cytarabine 5'-monophosphate
• Cytosine arabinoside 5'-monophosphate
• Cytosine arabinoside 5'-phosphate
• Cytosine arabinoside 5'MP
• Cytosine arabinoside monophosphate
• Nsc 99445
• 2(1H)-Pyrimidinone, 4-amino-1-(5-O-phosphono-beta-D-arabinofuranosyl)-
• Cytosine, 1-beta-D-arabinofuranosyl-, 5'-(dihydrogen phosphate) (8CI)
• 4-amino-1-(5-O-phosphono-beta-D-arabinofuranosyl)pyrimidin-2(1H)-one
• 1-β-D-Arabinofuranosylcytosine 5'-monophosphate
• 4-AMino-1-(5-O-phosphono-β-D-arabinofuranosyl)-
• CYTOSINE BETA-D-ARABINOFURANOSIDE 5'-MONOPHOSPHATE
• cytosine B-D-arabinofuranoside*5'-monophosphate F
• ARA-CMP
• 4-Amino-1-(5-O-phosphono-β-D-arabinofuranosyl)-1,2-dihydropyrimidin-2-one
• [(2R,3S,4S,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate
• ((2R,3S,4S,5R)-5-(4-AMino-2-oxopyriMidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)Methyl dihydrogen phosphate
• cytosine β-d-arabinofuranoside 5'-monophosphate
• 4-Amino-1-[5-O-(dihydroxyphosphinyl)-β-D-arabinofuranosyl]pyrimidine-2(1H)-one
• 1-beta-d-arabinofuranosylcytosine5’-monophosphate
• ((2R,3S,4S,5R)
• CYTOSINE B-D-ARABINOFURANOSIDE5'-MONOPHO SPHATE FRE
• Cytarabine Monophosphate
• 4-Amino-1-(5-O-phosphono--D-arabinofuranosyl)-2(1H)-pyrimidinone
• Cytarabine Impurity 8
• 1--D-Arabinofuranosylcytosine 5'-Monophosphate
• Cytarabine 5a€-Monophosphate
• 5'-Monophosphate cytosine arabiniside
• 1-(2-Oxo-1,2-dihydro-4-aminopyrimidine-1-yl)-1-deoxy-β-D-arabinofuranose 5-phosphoric acid
• Cytosine--D-arabinofuranoside-5'-monophosphoric Acid
• 1-β-D-adenosineabinofuranosylcytosine-5'-monophosphate
• 2(1H)-Pyrimidinone, 4-amino-1-(5-O-phosphono-β-D-arabinofuranosyl)-
• 2(1H)-Pyrimidinone,4-amino-1-(5-O-phosphono-b-D-arabinofuranosyl)-
• Cytosine-beta-D-arabinofuranoside-5zzhlxy-monophosphate

2(1H)-Pyrimidinone, 4-amino-1-(5-O-phosphono-b-D-arabinofuranosyl)-

CAS: 7075-11-8

Fórmula: C₉H₁₄N₃O₈P

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 323.1965

Ref: IN-DA00IC3K

Cytosine-β-D-arabinofuranoside-5''-monophosphate

CAS: 7075-11-8

Fórmula: C₉H₁₄N₃O₈P

Pureza: ≥ 99.0%

Cor e Forma: White to off-white powder

Peso molecular: 323.20

Ref: 7W-GE8537

Cytarabine Monophosphate

CAS: 7075-11-8

Fórmula: C₉H₁₄N₃O₈P

Peso molecular: 323.20

Ref: 4Z-C-150003

Cytarabine-13C3 5’-Monophosphate

Produto Controlado

CAS: 7075-11-8

Stability Hygroscopic
Applications A labelled derivative of Cytarabine, a potent cytotoxic-antiviral nucleoside.
References Kufe, D., et al.: J. Biol. Chem., 255, 8997 (1980), Ross, D., et al.: Cancer Res., 50, 2658 (1990), Bhalla, K., et al.: Blood, 80, 2883 (1992), Tonetti, D., et al.: J. Biol. Chem., 269, 23230 (1994),

Fórmula: C₆C₃H₁₄N₃O₈P

Cor e Forma: Neat

Peso molecular: 326.17

Ref: TR-C998107

Cytarabine 5’-Monophosphate

Produto Controlado

CAS: 7075-11-8

Stability Hygroscopic, Unstable in Solution
Applications A derivative of Cytarabine, a potent cytotoxic-antiviral nucleoside.
References Kufe, D., et al.: J. Biol. Chem., 255, 8997 (1980), Ross, D., et al.: Cancer Res., 50, 2658 (1990), Bhalla, K., et al.: Blood, 80, 2883 (1992), Tonetti, D., et al.: J. Biol. Chem., 269, 23230 (1994),

Fórmula: C₉H₁₄N₃O₈P

Cor e Forma: Neat

Peso molecular: 323.20

Ref: TR-C998105

1-(β-D-Arabinofuranosyl)cytosine 5'-monophosphate

CAS: 7075-11-8

1-(β-D-Arabinofuranosyl)cytidine 5'-monophosphate (ara-CMP) is a nucleotide derivative of cytidine, specifically a nucleotide where the ribose sugar is replaced by the arabinose sugar. It's a pyrimidine nucleotide commonly known as Cytarabine 5'-monophosphate or arabinosylcytosine 5'-monophosphate.

Fórmula: C₉H₁₄N₃O₈P

Pureza: Min. 95 Area-%

Cor e Forma: White Powder

Peso molecular: 323.2 g/mol

Ref: 3D-NA10080

Cytarabine 5′-monophosphate

CAS: 7075-11-8

Cytarabine 5′-monophosphate (ara-CMP), an active metabolite of the nucleoside analog cytarabine formed by deoxycytidine kinase, is incorporated into DNA by DNA polymerase α, significantly slowing DNA synthesis. It inhibits nuclear and mitochondrial DNA replication in S. cerevisiae at 15 mM and improves survival in an L1210 murine leukemia model at 3.5-75.1 mg/kg.

Fórmula: C₉H₁₄N₃O₈P

Cor e Forma: Solid

Peso molecular: 323.198

Ref: TM-T84932