CAS 71989-23-6

N-Fmoc-L-isoleucina

Descrição:

N-Fmoc-L-isoleucina é um derivado do aminoácido isoleucina, caracterizado pela presença de um grupo protetor 9-fluorenilmetoxicarbonila (Fmoc) no terminus amino. Este composto é comumente utilizado na síntese de peptídeos como um bloco de construção devido à sua estabilidade e facilidade de remoção do grupo Fmoc em condições básicas suaves. N-Fmoc-L-isoleucina mantém as propriedades essenciais da isoleucina, incluindo sua natureza hidrofóbica e capacidade de participar em várias interações dentro das cadeias de peptídeos. O grupo Fmoc aumenta a solubilidade do aminoácido em solventes orgânicos, facilitando sua incorporação em peptídeos. Além disso, N-Fmoc-L-isoleucina é tipicamente branco a off-white em aparência e é solúvel em solventes orgânicos comuns como dimetilformamida (DMF) e dimetilsulfóxido (DMSO). Sua estrutura molecular permite a formação de ligações peptídicas estáveis, tornando-o um componente valioso na síntese de peptídeos e proteínas biologicamente ativos.

Fórmula: C₂₁H₂₃NO₄

InChI: InChI=1S/C21H23NO4/c1-3-13(2)19(20(23)24)22-21(25)26-12-18-16-10-6-4-8-14(16)15-9-5-7-11-17(15)18/h4-11,13,18-19H,3,12H2,1-2H3,(H,22,25)(H,23,24)/t13-,19-/m0/s1

Chave InChI: InChIKey=QXVFEIPAZSXRGM-DJJJIMSYSA-N

SMILES: C(OC(N[C@@H]([C@H](CC)C)C(O)=O)=O)C1C=2C(C=3C1=CC=CC3)=CC=CC2

Sinónimos:

• (2S,3R)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-3-methylpentanoate
• (2S,3S)-2-(((9-Fluorenylmethoxy)carbonyl)amino)-3-methylpentanoic acid
• 2-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-3-methylpentanoic acid
• <span class="text-smallcaps">L</span>-Isoleucine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
• Fmoc-Ile-OH
• Fmoc-L-isoleucine
• Fmoc-lle-OH
• N-(9-Fluorenylmethoxycarbonyl)-<span class="text-smallcaps">L</span>-isoleucine
• N-(9-Fluorenylmethoxycarbonyl)isoleucine
• N-Fmoc-<span class="text-smallcaps">L</span>-isoleucine
• N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-<span class="text-smallcaps">L</span>-isoleucine
• N-[(9H-Fluoren-9-ylmethoxy)carbonyl]isoleucin
• N-[(9H-Fluoren-9-ylmethoxy)carbonyl]isoleucine
• N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alloisoleucine
• N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-isoleucine
• NSC 334289
• isoleucine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
• N-(9-Fluorenylmethoxycarbonyl)-L-isoleucine
• L-Isoleucine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-isoleucine

CAS: 71989-23-6

Fórmula: C₂₁H₂₃NO₄

Cor e Forma: White to Almost white powder to crystal

Peso molecular: 353.42

Ref: 3B-F0294

Fmoc-Ile-OH

CAS: 71989-23-6

Bachem ID: 4003168.

Fórmula: C₂₁H₂₃NO₄

Pureza: 99.87%

Cor e Forma: White

Peso molecular: 353.42

Ref: 01-4003168

Fmoc-L-Isoleucine

CAS: 71989-23-6

Fórmula: C₂₁H₂₃NO₄

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 353.4116

Ref: IN-DA0036PS

Fmoc-Ile-OH

CAS: 71989-23-6

Fmoc-Ile-OH

Pureza: ≥98%

Peso molecular: 353.41g/mol

Ref: 54-BUP19430

Fmoc-Ile-OH

CAS: 71989-23-6

Fórmula: C₂₁H₂₃NO₄

Pureza: ≥ 99.0%

Cor e Forma: White powder

Peso molecular: 353.42

Ref: 7W-GM4384

Fmoc-lle-OH

CAS: 71989-23-6

M03362 - Fmoc-lle-OH

Fórmula: C₂₁H₂₃NO₄

Pureza: 98%

Cor e Forma: Powder or Crystalline Powder

Peso molecular: 353.418

Ref: 10-M03362

Fmoc-Ile-OH

CAS: 71989-23-6

Fmoc-Ile-OH (Fmoc-L-isoleucine) is an Fmoc-modified isoleucine with a strong affinity for peptides and proteins and can be used to synthesize other active

Fórmula: C₂₁H₂₃NO₄

Pureza: 99.75%

Cor e Forma: Solid

Peso molecular: 353.41

Ref: TM-T67562

L-Isoleucine, FMOC protected

CAS: 71989-23-6

L-Isoleucine, FMOC protected

Fórmula: C₂₁H₂₃NO₄

Pureza: 95%

Cor e Forma: white powder

Peso molecular: 353.41g/mol

Ref: 54-OR0490

Fmoc-Ile-OH (N-Fmoc-L-isoleucine)

CAS: 71989-23-6

Fórmula: C₂₁H₂₃NO₄

Peso molecular: 353.42

Ref: 4Z-L-117014

Fmoc-Ile-OH

CAS: 71989-23-6

Fmoc-Ile-OH is a sodium salt that is used in the synthesis of peptides. It provides the hydroxyl group to the peptide chain, and can be used in solid-phase synthesis. The protonated form of Fmoc-Ile-OH is useful for acetonitrile solvents. Fmoc-Ile-OH has shown antibacterial activity against gram-positive bacteria such as Staphylococcus aureus and Streptococcus pneumoniae. Clinical development of this drug has been successful in treating infections caused by multidrug resistant bacteria, such as MRSA, Acinetobacter baumannii, and Pseudomonas aeruginosa.

Fórmula: C₂₁H₂₃NO₄

Pureza: Min. 98.0 Area-%

Peso molecular: 353.42 g/mol

Ref: 3D-FLI-1724-PI

FMOC-L-Isoleucine extrapure, 99%

CAS: 71989-23-6

Fórmula: C₂₁H₂₃NO₄

Pureza: min. 99%

Cor e Forma: White, Crystalline powder

Peso molecular: 353.40

Ref: SR-22834

N-Fmoc-L-isoleucine

Produto Controlado

CAS: 71989-23-6

Applications N-Fmoc-L-isoleucine is a N-Fmoc-protected form of L-Isoleucine (I820175). L-Isoleucine is classified as an essential amino acid, and is also a tumour promoter of bladder cancer in rats.
References Hatch, T., et al.: Infect. Immun., 12, 211 (1975); Nishio, Y., et al.: Science, 231, 843 (1986)

Fórmula: C₂₁H₂₃NO₄

Cor e Forma: Neat

Peso molecular: 353.41

Ref: TR-F625025

N-Fmoc-L-isoleucine-d10

Produto Controlado

CAS: 71989-23-6

Applications N-Fmoc-L-isoleucine-d10 is the labeled analogue of N-Fmoc-L-isoleucine (F625025), a N-Fmoc-protected form of L-Isoleucine (I820175). L-Isoleucine is classified as an essential amino acid, and is also a tumour promoter of bladder cancer in rats.
References Hatch, T., et al.: Infect. Immun., 12, 211 (1975); Nishio, Y., et al.: Science, 231, 843 (1986)

Fórmula: C₂₁D₁₀H₁₃NO₄

Cor e Forma: Neat

Peso molecular: 363.473

Ref: TR-F625027

Fmoc-Ile-OH

CAS: 71989-23-6

Fmoc-Ile-OH is a cyclic peptide that has shown cytotoxic activity against cultured human brain cells. It is also an inhibitor of dipeptidyl peptidase IV (DPP-IV) and inhibits the breakdown of proteins in the brain, such as insulin. Fmoc-Ile-OH binds to the active site of DPP-IV and prevents it from binding to its substrate, thereby inhibiting the enzyme's activity. The inhibition of DPP-IV leads to increased levels of protein in the brain, which may be beneficial for people with Alzheimer's disease. Fmoc-Ile-OH is synthesized on a solid phase by coupling an amino acid with a protected carboxylic acid to yield a protected amide. This product can be used as an encapsulating agent for atosiban, a drug that is used to treat preterm labor.END>>

Fórmula: C₂₁H₂₃NO₄

Pureza: Min. 98 Area-%

Cor e Forma: White Off-White Powder

Peso molecular: 353.41 g/mol

Ref: 3D-FF15881