CAS 71989-31-6

Fmoc-Pro-OH

Descrição:

Fmoc-Pro-OH, ou 9-fluorenilmetoxicarbonila-prolina, é um aminoácido protegido comumente utilizado na síntese de peptídeos. Apresenta um grupo fluorenilmetoxicarbonila (Fmoc), que serve como um grupo protetor para a funcionalidade amino da prolina, permitindo reações seletivas durante a montagem de peptídeos. O grupo Fmoc é estável em condições básicas, mas pode ser removido em condições ácidas suaves, facilitando a etapa de desproteção na síntese de peptídeos. Fmoc-Pro-OH é caracterizado por sua relativamente alta solubilidade em solventes orgânicos, como dimetilformamida (DMF) e diclorometano, enquanto é menos solúvel em água. Este composto é crucial na síntese de peptídeos em fase sólida, onde ajuda na adição sequencial de aminoácidos para formar peptídeos. Sua estrutura inclui um esqueleto de prolina, que introduz propriedades conformacionais únicas devido à sua estrutura cíclica, influenciando a estrutura secundária geral do peptídeo. O número CAS 71989-31-6 identifica de forma única este composto, garantindo comunicação precisa na literatura científica e bancos de dados.

Fórmula: C₂₀H₁₉NO₄

InChI: InChI=1S/C20H19NO4/c22-19(23)18-10-5-11-21(18)20(24)25-12-17-15-8-3-1-6-13(15)14-7-2-4-9-16(14)17/h1-4,6-9,17-18H,5,10-12H2,(H,22,23)/t18-/m0/s1

Chave InChI: InChIKey=ZPGDWQNBZYOZTI-SFHVURJKSA-N

SMILES: C(OC(=O)N1[C@H](C(O)=O)CCC1)C2C=3C(C=4C2=CC=CC4)=CC=CC3

Sinónimos:

• (2S)-1-[(9H-Fluoren-9-ylmethoxy)carbonyl]pyrrolidine-2-carboxylic acid
• (2S)-1-[[(9H-Fluoren-9-yl)methoxy]carbonyl]pyrrolidine-2-carboxylic acid
• (S)-N-(9-Fluorenylmethoxycarbonyl)proline
• (S)-hidrogenopirrolidina-1,2-dicarboxilato de 1-(9H-fluoren-9-ilmetilo)
• (S)-hydrogenopyrrolidine-1,2-dicarboxylate de 1-(9H-fluorene-9-ylmethyle)
• 1,2-Pyrrolidinedicarboxylic acid, 1-(9H-fluoren-9-ylmethyl) ester, (S)-
• 1-(9H-fluoren-9-ylmethyl) hydrogen (S)-pyrrolidine-1,2-dicarboxylate
• 1-(9H-fluoren-9-ylmethyl)-(S)-hydrogenpyrrolidin-1,2-dicarboxylat
• Fluorenylmethoxycarbonylproline
• Fmoc-<span class="text-smallcaps">L</span>-Pro-OH
• Fmoc-<span class="text-smallcaps">L</span>-proline
• Fmoc-L-proline
• Fmoc-Pro-OH
• N-(9-Fluorenylmethoxycarbonyl)-<span class="text-smallcaps">L</span>-proline
• N-(9-Fluorenylmethoxycarbonyl)-L-proline
• N-(9-Fluorenylmethoxycarbonyl)proline
• N-FMOC-<span class="text-smallcaps">L</span>-proline
• N-FMOC-L-proline
• Nsc 334294

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-proline

CAS: 71989-31-6

Fórmula: C₂₀H₁₉NO₄

Pureza: >98.0%(T)(HPLC)

Cor e Forma: White to Almost white powder to crystal

Peso molecular: 337.38

Ref: 3B-F0298

N-Fmoc-L-proline, 98%

CAS: 71989-31-6

It is used as pharmaceutical intermediate. Fmoc method is used for the synthesis of the new polymeric support for the preparation of C-terminal peptide amides. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label inform

Fórmula: C₂₀H₁₉NO₄

Pureza: 98%

Cor e Forma: Crystals or powder or crystalline powder, White to pale cream

Peso molecular: 337.38

Ref: 02-B21081

Fmoc-Pro-OH

CAS: 71989-31-6

M03372 - Fmoc-Pro-OH

Fórmula: C₂₀H₁₉NO₄

Pureza: 98%

Cor e Forma: Solid, Crystalline or Powder

Peso molecular: 337.375

Ref: 10-M03372

Fmoc-Pro-OH

CAS: 71989-31-6

Bachem ID: 4003150.

Fórmula: C₂₀H₁₉NO₄

Pureza: 99.8%

Cor e Forma: White

Peso molecular: 337.38

Ref: 01-4003150

Fmoc-Pro-OH

CAS: 71989-31-6

Fórmula: C₂₀H₁₉NO₄

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 337.3692

Ref: IN-DA003QO0

Fmoc-L-Proline

CAS: 71989-31-6

Fmoc-L-Proline (Fmoc-Pro-OH) is a proline derivative.

Fórmula: C₂₀H₁₉NO₄

Pureza: 99.22%

Cor e Forma: Solid

Peso molecular: 337.37

Ref: TM-T64331

Fmoc-L-Proline, 10mM (in DMSO)

CAS: 71989-31-6

Fmoc-L-Proline, 10mM (in DMSO)

Pureza: ≥98%

Peso molecular: 337.37g/mol

Ref: 54-BUP19106

Fmoc-Pro-OH

CAS: 71989-31-6

Fórmula: C₂₀H₁₉NO₄

Pureza: ≥ 99.0%

Cor e Forma: White to off-white or pale yellow crystalline powder

Peso molecular: 337.38

Ref: 7W-GM2265

FMOC-Pro-OH

CAS: 71989-31-6

FMOC-Pro-OH

Fórmula: C₂₀H₁₉NO₄

Pureza: 98%

Cor e Forma: white to off white powder

Peso molecular: 337.37g/mol

Ref: 54-OR54567

L-Proline-2,5,5-d3-N-FMOC

CAS: 71989-31-6

Pureza: 98 atom % D

Cor e Forma: White Solid

Peso molecular: 340.39

Ref: 3U-D7565

Fmoc-Pro-OH

CAS: 71989-31-6

Fórmula: C₂₀H₁₉NO₄

Peso molecular: 337.38

Ref: 4Z-P-166009

Fmoc-Pro-OH

CAS: 71989-31-6

Fmoc-Pro-OH is a synthetic cyclic peptide with the amino acid sequence (Fmoc-Lys-Lys-Ala-Glu)n. Fmoc-Pro-OH binds to the androgen receptor and can be used as a research tool to identify other molecules that bind to the same receptor. It has been shown to inhibit the activity of ester hydrochloride, trifluoroacetic acid, and superparamagnetic iron in coordination complexes.

Fórmula: C₂₀H₁₉NO₄

Pureza: Min. 95 Area-%

Cor e Forma: White Off-White Powder

Peso molecular: 337.37 g/mol

Ref: 3D-FF15871

Fmoc-Pro-OH

CAS: 71989-31-6

Fmoc-Pro-OH is a peptide that contains the Fmoc protecting group. It is used in the synthesis of peptides and has been shown to be effective against microbial infections with marine sponges. The synthesis of this compound can be carried out on an on-line automated peptide synthesizer. The Fmoc protecting group is removed by treatment with trifluoroacetic acid (TFA) in dichloromethane, which leaves the side chain unprotected. This compound has a high binding affinity for the receptor site of fibrinogen and can potentially inhibit the growth of bacteria that cause bacterial infection, such as Staphylococcus aureus and Pseudomonas aeruginosa.
Fmoc-Pro-OH can also be used to synthesize other functional groups such as sulfamoyl groups or acetonitrile groups, depending on the desired outcome.

Fórmula: C₂₀H₁₉NO₄

Pureza: Min. 98 Area-%

Peso molecular: 337.38 g/mol

Ref: 3D-FLP-1731-PI

FMOC-L-Proline extrapure, 99%

CAS: 71989-31-6

Fórmula: C₂₀H₁₉NO₄

Pureza: min. 99%

Cor e Forma: White to Off white, Crystalline powder

Peso molecular: 337.38

Ref: SR-12047

L-Proline-N-Fmoc

Produto Controlado

CAS: 71989-31-6

Applications L-Proline-N-Fmoc is N-Fmoc protected L-Proline (P755995) which is an amino acid and precursor (with vitamin C) for collagen, the building block of the structure of tendons, ligaments, arteries, veins and muscles. It is important in wound healing.
References Bondarenko, L.B., et al.: Int. J. Peptides., 2, 1687 (2012); Rimer, T., et al.: Biomacromolecules, 13, 2110 (2012);

Fórmula: C₂₀H₁₉NO₄

Cor e Forma: Neat

Peso molecular: 337.37

Ref: TR-P756005

L-Proline-d3-N-Fmoc

Produto Controlado

CAS: 71989-31-6

Applications L-Proline-d3-N-Fmoc was used to prepare potent bombesin-like peptides for GRP-receptor targeting of tumors. It was also used to synthesize tetrapeptide aldehyde inhibitors of dengue virus NS3 protease.
References Nock, B., et al.: J. Med. Chem., 48, 100 (2005); Yin, Z., et al.: Bioorg. Med. Chem. Lett., 16, 40 (2006)

Fórmula: C₂₀D₃H₁₆NO₄

Cor e Forma: Neat

Peso molecular: 340.39

Ref: TR-P756007