CAS 71989-35-0

N-(9-Fluorenilmetoxicarbonil)-O-terc-butiltreonina

Descrição:

N-(9-Fluorenilmetoxicarbonil)-O-terc-butiltreonina, comumente referido como Fmoc-O-t-Bu-Thr, é um derivado de aminoácido protegido amplamente utilizado na síntese de peptídeos. Este composto apresenta um grupo 9-fluorenilmetoxicarbonila (Fmoc), que serve como um grupo protetor para a funcionalidade amino, permitindo reações seletivas durante a montagem de peptídeos. O grupo tert-butilo na cadeia lateral da treonina fornece impedância estérica, aumentando a estabilidade da molécula e facilitando os processos de purificação. Fmoc-O-t-Bu-Thr é tipicamente utilizado na síntese de peptídeos em fase sólida, onde o grupo Fmoc pode ser facilmente removido em condições básicas, permitindo o acoplamento subsequente de aminoácidos. O composto é caracterizado por sua estabilidade relativamente alta em condições laboratoriais padrão, tornando-o adequado para várias aplicações sintéticas. Sua solubilidade em solventes orgânicos e solubilidade moderada em água contribuem ainda mais para sua utilidade na química de peptídeos. No geral, Fmoc-O-t-Bu-Thr é um bloco de construção essencial na síntese de peptídeos, particularmente no contexto do desenvolvimento de agentes terapêuticos e ferramentas de pesquisa em bioquímica.

Fórmula: C₂₃H₂₇NO₅

InChI: InChI=1/C23H27NO5/c1-14(29-23(2,3)4)20(21(25)26)24-22(27)28-13-19-17-11-7-5-9-15(17)16-10-6-8-12-18(16)19/h5-12,14,19-20H,13H2,1-4H3,(H,24,27)(H,25,26)/p-1/t14-,20+/m1/s1

Chave InChI: InChIKey=LZOLWEQBVPVDPR-VLIAUNLRSA-N

SMILES: C(OC(N[C@@H]([C@H](OC(C)(C)C)C)C(O)=O)=O)C1C=2C(C=3C1=CC=CC3)=CC=CC2

Sinónimos:

• (2S,3R)-2-(((9-Fluorenylmethoxy)carbonyl)amino)-3-(tert-butoxy)butanoic acid
• (2S,3R)-3-tert-Butoxy-2-[[[[9H-fluoren-9-yl]methoxy]carbonyl]amino)butanoic acid
• (2S,3R)-3-tert-butoxy-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}butanoate
• <span class="text-smallcaps">L</span>-Threonine, O-(1,1-dimethylethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
• FMOC-O-tert-Butyl-L-threonine
• Fmoc-L-Thr(tBu)-OH
• Fmoc-Thr(OtBu)-OH
• N-(9-Fluorenylmethoxycarbonyl)-O-tert-butylthreonine
• O-(1,1-Dimethylethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-<span class="text-smallcaps">L</span>-threonine
• O-tert-butyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-threonine
• O-tert-butyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]threonine
• L-Threonine, O-(1,1-dimethylethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
• O-(1,1-Dimethylethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-threonine
• N-9-FLUORENYLMETHYLOXYCARBONYL-O-TERT-BUTYL-L-THREONINE
• N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-O-T-BUTYL-L-THREONINE
• FMOC-L-THR(O-T-BUTYL)
• FMOC-THR(TBU)
• FMOC-THREONINE(TBU)-OH
• FMOC-L-THREONINE (TBU)
• FMOC-L-THREONINE(O-T-BUTYL)
• 9-FLUORENYLMETHOXYCARBONYL-O-T-BUTYL-L-THREONINE
• FMOC-O-T-BUTYL-L-THREONINE
• N-(9-FLUORENYL METHOXY CARBONYL)-O-TERT-BUTYL-L-THREONINE
• FMOC-THR(BUT)
• NALPHA-(9-FLUORENYLMETHOXYCARBONYL)-O-TERT-BUTYL-L-THREONINE
• N-(9-FLUORENYLMETHOXYCARBONYL)-O-TERT-BUTYL-L-THRETONINE
• FMOC-THR(TBU)-OH
• N-9-FLUORENYLMETHYLOXYCARBONYL-O-T-BUTYL-L-THREONINE
• FMOC-THR(BUT)-OH
• 9-FLUORENYLMETHOXYCARBONYL-O-T-BUTYL-L-THEONINE

Fmoc-Thr(tBu)-OH

CAS: 71989-35-0

M03389 - Fmoc-Thr(tBu)-OH

Fórmula: C₂₃H₂₇NO₅

Pureza: 97%

Cor e Forma: Crystalline,Powder

Peso molecular: 397.471

Ref: 10-M03389

Nα-Fmoc-O-tert-butyl-L-threonine, 98%

CAS: 71989-35-0

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Fórmula: C₂₃H₂₇NO₅

Pureza: 98%

Cor e Forma: White, Powder

Peso molecular: 397.47

Ref: 02-H59808

Fmoc-Thr(tBu)-OH

CAS: 71989-35-0

Bachem ID: 4096755.

Fórmula: C₂₃H₂₇NO₅

Pureza: 99.9%

Cor e Forma: White

Peso molecular: 397.47

Ref: 01-4096755

(2S,3R)-2-(((9-Fluorenylmethoxy)carbonyl)amino)-3-(tert-butoxy)butanoic acid

CAS: 71989-35-0

Fórmula: C₂₃H₂₇NO₅

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 397.4642

Ref: IN-DA0034Y8

Fmoc-Thr(tBu)-OH

CAS: 71989-35-0

Fórmula: C₂₃H₂₇NO₅

Pureza: ≥ 98.0%

Cor e Forma: White to off-white powder

Peso molecular: 397.46

Ref: 7W-GM9332

Nα-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-tert-butyl-L-threonine

CAS: 71989-35-0

Fórmula: C₂₃H₂₇NO₅

Pureza: >98.0%(T)(HPLC)

Cor e Forma: White to Light yellow powder to crystal

Peso molecular: 397.47

Ref: 3B-F0505

Fmoc-O-tert-Butyl-L-threonine

CAS: 71989-35-0

Fmoc-O-tert-Butyl-L-threonine

Pureza: 98%

Cor e Forma: Powder

Peso molecular: 397.46g/mol

Ref: 54-OR350183

Fmoc-Thr(tBu)-OH

CAS: 71989-35-0

Fmoc-Thr(tBu)-OH is an ester hydrochloride that is synthesized by reacting the amino acid, Fmoc-Thr(tBu) with trifluoroacetic acid. It has been used to synthesize a cyclic peptide with a protonated amide group, which allows for stereoselective synthesis of the chloride. This product has shown to be resistant to hydrolysis by atosiban and carbonyl oxygens, and also binds to mammalian cell receptors.

Fórmula: C₂₃H₂₇NO₅

Pureza: Min. 98 Area-%

Cor e Forma: White Powder

Peso molecular: 397.46 g/mol

Ref: 3D-FF15778

Fmoc-Thr(tBu)-OH

CAS: 71989-35-0

Fmoc-Thr(tBu)-OH is an amino acid that is used for the synthesis of amides and esters. It is prepared by the solid-phase synthesis of 2,6-dichloroacetic acid and Fmoc-protected thiomorpholine. The product can be purified by a combination of saponification and trifluoroacetic acid hydrolysis. This amino acid has acidic properties, which may be due to its ability to form ester or amide bonds with other compounds in the presence of a base.

Fórmula: C₂₃H₂₇NO₅

Pureza: Min. 98.0 Area-%

Peso molecular: 397.48 g/mol

Ref: 3D-FLT-1700-PI