CAS 71989-38-3

Fmoc-L-Tyr(tBu)-OH

Descrição:

Fmoc-L-Tyr(tBu)-OH, também conhecido como 9-fluorenilmetoxicarbonila-L-tirosina (tert-butilo), é uma forma protegida do aminoácido tirosina, comumente utilizada na síntese de peptídeos. O grupo Fmoc serve como um grupo protetor para a funcionalidade amino, permitindo reações seletivas sem interferir com a cadeia lateral do aminoácido. O grupo tert-butilo (tBu) protege o grupo hidroxila da cadeia lateral da tirosina, melhorando a estabilidade e solubilidade do composto durante a síntese. Este composto é tipicamente um sólido branco a off-white e é solúvel em solventes orgânicos como dimetilsulfóxido (DMSO) e diclorometano, mas menos solúvel em água. Sua estrutura molecular inclui um anel de fluoreno, que contribui para sua estabilidade e facilidade de remoção em condições suaves durante as etapas de desproteção na síntese de peptídeos. Fmoc-L-Tyr(tBu)-OH é amplamente utilizado no campo da química orgânica e bioquímica para a síntese de peptídeos e proteínas, facilitando a introdução de resíduos de tirosina em construções moleculares maiores.

Fórmula: C₂₈H₂₉NO₅

InChI: InChI=1/C28H29NO5/c1-28(2,3)34-19-14-12-18(13-15-19)16-25(26(30)31)29-27(32)33-17-24-22-10-6-4-8-20(22)21-9-5-7-11-23(21)24/h4-15,24-25H,16-17H2,1-3H3,(H,29,32)(H,30,31)

Chave InChI: InChIKey=JAUKCFULLJFBFN-VWLOTQADSA-N

SMILES: C(OC(N[C@@H](CC1=CC=C(OC(C)(C)C)C=C1)C(O)=O)=O)C2C=3C(C=4C2=CC=CC4)=CC=CC3

Sinónimos:

• (2S)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-[4-[(2-methylpropan-2-yl)oxy]phenyl]propanoic acid
• (2S)-3-[4-(tert-Butoxy)phenyl]-2-([[(9H-fluoren-9-yl)methoxy]carbonyl]amino)propanoic acid
• (S)-3-(4-tert-Butoxyphenyl)-2-[[[(9H-fluoren-9-yl)methoxy]carbonyl]amino]propionic acid
• <span class="text-smallcaps">L</span>-Tyrosine, O-(1,1-dimethylethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
• Fmoc-L-Tyr(tBu)-OH
• Fmoc-Tyr(But)-OH
• Fmoc-Tyr(OtBu)-OH
• Fmoc-Tyr(tBu)-OH
• N-(9-Fluorenyl Methoxy Carbonyl)-O-Tertbutyl-L-Tyrosine
• N-alpha-(9-fluorenylmethyloxycarbonyl)-O-t-butyl-L-tyrosine
• N-fmoc-O-T-butyl-L-tyrosine
• NSC 334301
• O-(1,1-Dimethylethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-<span class="text-smallcaps">L</span>-tyrosine
• O-tert-butyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]tyrosine
• Tyr(tBu)
• O-(1,1-Dimethylethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-tyrosine
• L-Tyrosine, O-(1,1-dimethylethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
• Fmoc-O-tert.butyl-L-tyrosine
• FMOC-L-TYR(T-BU)
• N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-O-TERT-BUTYL-L-TYROSINE
• N-(9-FLUORENYLMETHOXYCARBONYL)-O-TERT-BUTYL-L-TYROSINE
• FMOC-L-TYR(O-T-BUTYL)
• FMOC-O-T-BUTYL-L-TYROSINE
• FMOC-TYR(BUT)
• FMOC-TYR(TRT)-OH
• N-9-FLUORENYLMETHYLOXYCARBONYL-O-T-BUTYL-L-TYROSINE
• FMOC-L-TYROSINE(O-T-BUTYL)
• FMOC-L-TYROSINE (TBU)
• FMOC-TYR(TBU)
• N-9-FLUORENYLMETHYLOXYCARBONYL-O-TERT-BUTYL-L-TYROSINE
• FMOC-TYROSINE(TBU)-OH
• 9-FLUORENYLMETHOXYCARBONYL-O-T-BUTYL-L-TYROSINE

Fmoc-Tyr(tBu)-OH

CAS: 71989-38-3

M03428 - Fmoc-Tyr(tBu)-OH

Fórmula: C₂₈H₂₉NO₅

Pureza: 98%

Cor e Forma: Crystalline Powder,Powder

Peso molecular: 459.542

Ref: 10-M03428

N-Fmoc-O-tert-butyl-L-tyrosine, 98%

CAS: 71989-38-3

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Fórmula: C₂₈H₂₉NO₅

Pureza: 98%

Peso molecular: 459.54

Ref: 02-H59730

Fmoc-Tyr(tBu)-OH

CAS: 71989-38-3

Bachem ID: 4093144.

Fórmula: C₂₈H₂₉NO₅

Pureza: 99.8%

Cor e Forma: White

Peso molecular: 459.54

Ref: 01-4093144

Fmoc-O-tert-butyl-L-tyrosine

CAS: 71989-38-3

Fórmula: C₂₈H₂₉NO₅

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 459.5336

Ref: IN-DA0034Y7

Fmoc-L-Tyr(tBu)-OH

CAS: 71989-38-3

Fmoc-L-Tyr(tBu)-OH

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 459.53g/mol

Ref: 54-BI467

Fmoc-Tyr(tBu)-OH

CAS: 71989-38-3

Fórmula: C₂₈H₂₉NO₅

Pureza: ≥ 99.0%

Cor e Forma: White to almost white powder

Peso molecular: 459.53

Ref: 7W-GM6164

Nα-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-tert-butyl-L-tyrosine

CAS: 71989-38-3

Fórmula: C₂₈H₂₉NO₅

Pureza: >98.0%(T)(HPLC)

Cor e Forma: White to Almost white powder to crystal

Peso molecular: 459.54

Ref: 3B-F0506

Fmoc-Tyr(tBu)-OH

CAS: 71989-38-3

Fmoc-Tyr(tBu)-OH is a protected amino acid for solid-phase peptide synthesis, enabling Leu-EnkephalinAmide formation and versatile amino acid derivatives.

Fórmula: C₂₈H₂₉NO₅

Pureza: 99.89%

Cor e Forma: Solid

Peso molecular: 459.54

Ref: TM-T67575

Fmoc-Tyr(tBu)-OH

CAS: 71989-38-3

Fmoc-Tyr(tBu)-OH is an amide that binds to the natriuretic receptor. It has a disulfide bond with a hydroxyapatite, which makes it more stable and inhibits its degradation. Fmoc-Tyr(tBu)-OH is hemolytic in vitro and minimally toxic in vivo at high concentrations. It also has a hydroxyl group, which can be used to synthesize other molecules. Fmoc-Tyr(tBu)-OH also has antimicrobial properties, as it inhibits the growth of bacteria and fungi by binding to cell membranes and disrupting their integrity.br>br> Fmoc-Tyr(tBu)-OH is taken up by cells through sodium/hydrogen antiporter system. This uptake process is mediated by the protein Na+, K+ -ATPase, which provides energy for transport across the membrane.

Fórmula: C₂₈H₂₉NO₅

Pureza: Min. 98 Area-%

Cor e Forma: White Off-White Powder

Peso molecular: 459.53 g/mol

Ref: 3D-FF15877

Fmoc-Tyr(tBu)-OH

CAS: 71989-38-3

Fmoc-Tyr(tBu)-OH is a building block for the synthesis of peptides. It is reacted with tert-butyl alcohol and hydrochloric acid to produce the corresponding Fmoc-protected tyrosine. The Fmoc group can be removed by treatment with dicyclohexylcarbodiimide and tert-butyl alcohol, followed by saponification in aqueous base. The morphologies of the resulting free amino acids are determined by their solubility in organic solvents such as chloroform or ethyl acetate, as well as in water.

Fórmula: C₂₈H₂₉NO₅

Pureza: Min. 98.0 Area-%

Peso molecular: 459.53 g/mol

Ref: 3D-FLY-1737-PI

FMOC-O-Tert-Butyl-L-Tyrosine (FMOC-Tyr(tBu)-OH) extrapure, 98%

CAS: 71989-38-3

Fórmula: C₂₈H₂₉NO₅

Pureza: min. 98%

Cor e Forma: White, Crystalline powder

Peso molecular: 459.53

Ref: SR-22292

Fmoc-L-Tyr(tBu)-OH

Produto Controlado

CAS: 71989-38-3

Applications Fmoc-L-Tyr(tBu)-OH is tyrosine derivative used in soiid phase peptide synthesis.
References Atherton, E., et al.: J. Chem. Soc. Chem. Comm., 20, 970 (1980);

Fórmula: C₂₈H₂₉NO₅

Cor e Forma: Neat

Peso molecular: 459.53

Ref: TR-F622860