CAS 72957-38-1

fragmento de dinorfina A 1-13

Descrição:

fragmento de dinorfina A 1-13 é um peptídeo derivado da molécula maior dinorfina A, que faz parte da família de peptídeos opioides endógenos. Este fragmento consiste em 13 aminoácidos e é conhecido por seu papel na modulação da dor, respostas ao estresse e vários processos neurofisiológicos. Ele interage principalmente com os receptores kappa-opioides no sistema nervoso central, contribuindo para seus efeitos analgésicos. O peptídeo exibe características típicas de peptídeos opioides, incluindo a capacidade de induzir analgesia e influenciar o humor e as respostas emocionais. Sua estrutura inclui sequências específicas que são cruciais para a ligação e atividade do receptor. Além disso, fragmento de dinorfina A 1-13 pode ter implicações em várias condições neurológicas e é de interesse na pesquisa relacionada à dependência, depressão e outros transtornos de humor. Como um peptídeo sintético ou de ocorrência natural, pode ser estudado por suas propriedades farmacológicas e potenciais aplicações terapêuticas.

Fórmula: C₇₅H₁₂₆N₂₄O₁₅

InChI: InChI=1/C75H126N24O15/c1-7-45(6)61(70(111)94-53(25-17-35-87-75(83)84)71(112)99-36-18-26-58(99)69(110)93-50(21-11-13-31-76)64(105)96-56(38-44(4)5)67(108)95-54(72(113)114)22-12-14-32-77)98-65(106)52(24-16-34-86-74(81)82)91-63(104)51(23-15-33-85-73(79)80)92-66(107)55(37-43(2)3)97-68(109)57(40-46-19-9-8-10-20-46)90-60(102)42-88-59(101)41-89-62(103)49(78)39-47-27-29-48(100)30-28-47/h8-10,19-20,27-30,43-45,49-58,61,100H,7,11-18,21-26,31-42,76-78H2,1-6H3,(H,88,101)(H,89,103)(H,90,102)(H,91,104)(H,92,107)(H,93,110)(H,94,111)(H,95,108)(H,96,105)(H,97,109)(H,98,106)(H,113,114)(H4,79,80,85)(H4,81,82,86)(H4,83,84,87)/t45-,49-,50-,51-,52-,53-,54?,55-,56-,57-,58-,61-/m0/s1

SMILES: CC[C@H](C)[C@@H](C(=N[C@@H](CCCNC(=N)N)C(=O)N1CCC[C@H]1C(=N[C@@H](CCCCN)C(=N[C@@H](CC(C)C)C(=NC(CCCCN)C(=O)O)O)O)O)O)N=C([C@H](CCCNC(=N)N)N=C([C@H](CCCNC(=N)N)N=C([C@H](CC(C)C)N=C([C@H](Cc1ccccc1)N=C(CN=C(CN=C([C@H](Cc1ccc(cc1)O)N)O)O)O)O)O)O)O

Sinónimos:

• Dynorphin A (1-13)
• H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-OH
• Dynorphin A 1-13, Porcine

Dynorphin A (1-13)

CAS: 72957-38-1

Endogenous kappa-opioid receptor agonist. It is suggested that it attenuates galanin-induced impairment of memory processes through the mediation of kappa-opioid receptors.

Fórmula: C₇₅H₁₂₆N₂₄O₁₅

Pureza: 91.6%

Cor e Forma: White Powder

Peso molecular: 1603.98

Ref: 01-4004062

Dynorphin A (1-13) H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-OH

CAS: 72957-38-1

Fórmula: C₇₅H₁₂₆N₂₄O₁₅

Pureza: 98%

Peso molecular: 1603.9547

Ref: IN-DA01E9V2

Dynorphin A (1-13) Acetatexa0

CAS: 72957-38-1

Ref: 7W-GX0937

Dynorphin A(1-13) Acetate

CAS: 72957-38-1

Fórmula: C₇₅H₁₂₆N₂₄O₁₅

Pureza: 95%~99%

Cor e Forma: White to Off-white Powder

Peso molecular: 1603.97

Ref: BP-BPPG022

Porcine dynorphin A(1-13)

CAS: 72957-38-1

Porcine dynorphin A (1-13) is a potent κ opioid receptor agonist; it's antinociceptive and raises [Ca2+]i in neurons like NMDA.

Fórmula: C₇₅H₁₂₆N₂₄O₁₅

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 1603.95

Ref: TM-TP1179

Porcine Dynorphin A(1-13)

CAS: 72957-38-1

Porcine Dynorphin A(1-13)

Pureza: 99%

Peso molecular: 1,603.95g/mol

Ref: 54-BISN0009

Dynorphin A (1-13)

CAS: 72957-38-1

Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool

Fórmula: C₇₅H₁₂₆N₂₄O₁₅

Peso molecular: 1,603.95 g/mol

Ref: 3D-PP50465

Dynorphin A (1-12), porcine

CAS: 72957-38-1

Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool

Fórmula: C₆₉H₁₁₄N₂₂O₁₄

Peso molecular: 1,475.82 g/mol

Ref: 3D-PP50361

Dynorphin A (Human, 1-13)

CAS: 72957-38-1

As a dynorphin peptide, Dynorphin A has affinity for opioid receptors in particular it favors kappa-opioid receptors and residues 1-13 of the Dynorphin A peptide are crucial for its potency. Kappa-opioid receptors are expressed in the brain, peripheral tissues and the spinal cord and are located in areas involved in pain. For example when Dynorphin A binds to kappa-opioid receptors, dopamine is inhibited in areas of the brain prevalent in drug addiction, thus demonstrated Dynorphin A to have antagonistic effects on the brain reward circuit. Dynorphin A could be a useful research tool for studying analgesia, reward and addiction.
This product is available as a 0.5mg vial.

Fórmula: C₇₅H₁₂₆N₂₄O₁₅

Pureza: Min. 95%

Peso molecular: 1,604 g/mol

Ref: 3D-PDY-4080-V

Dynorphin A (porcine 1-13) - acetate salt

CAS: 72957-38-1

Dynorphin A (1-13) H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys is a peptide that is found in the brain and spinal cord. It is an agonist of opioid receptors, which are involved in pain relief, as well as motor control. Dynorphin A (1-13) H has been shown to inhibit acetylcholine release, which may be due to its ability to bind to kappa opioid receptors. Dynorphin A (1-13) H is also known to bind to κ opioid receptors, where it inhibits locomotor activity and induces analgesia.

Fórmula: C₇₅H₁₂₆N₂₄O₁₅

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 1,603.96 g/mol

Ref: 3D-FD108725

Dynorphin A (1-13), Porcine

CAS: 72957-38-1

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Cor e Forma: Lyophilized powder

Ref: 02-J64015