CAS 73816-42-9

Sulfossalicitato de meclociclina

Descrição:

Sulfossalicitato de meclociclina é um composto químico que pertence à classe dos antibióticos tetraciclínicos, conhecidos por sua atividade antibacteriana de amplo espectro. Esta substância é um derivado da meclociclina, caracterizada pela presença de um grupo sulfosalicilato que melhora sua solubilidade e biodisponibilidade. Ela exibe propriedades antibacterianas ao inibir a síntese de proteínas nas bactérias, tornando-a eficaz contra uma variedade de organismos gram-positivos e gram-negativos. Sulfossalicitato de meclociclina é tipicamente utilizado na medicina veterinária e também pode ter aplicações no tratamento de certas infecções em humanos. O composto é geralmente administrado por via oral ou parenteral, dependendo da formulação. Sua farmacocinética envolve absorção no trato gastrointestinal, distribuição por todo o corpo e excreção eventual principalmente pelos rins. Assim como outros tetraciclinas, pode ter efeitos colaterais, incluindo distúrbios gastrointestinais e efeitos potenciais no desenvolvimento de ossos e dentes em crianças. A dosagem e administração adequadas são cruciais para minimizar o desenvolvimento de resistência e garantir a eficácia terapêutica.

Fórmula: C₂₉H₂₇ClN₂O₁₄S

InChI: InChI=1/C22H21ClN2O8.C7H6O6S/c1-6-9-7(23)4-5-8(26)11(9)16(27)12-10(6)17(28)14-15(25(2)3)18(29)13(21(24)32)20(31)22(14,33)19(12)30;8-6-2-1-4(14(11,12)13)3-5(6)7(9)10/h4-5,10,14-15,17,26-28,32-33H,1,24H2,2-3H3;1-3,8H,(H,9,10)(H,11,12,13)/b21-13-;/t10-,14-,15+,17+,22+;/m1./s1

Chave InChI: InChIKey=FYSVKUUNXYGFLA-CCHMMTNSSA-N

SMILES: O[C@]12[C@]([C@H](N(C)C)C(O)=C(C(N)=O)C1=O)([C@@H](O)[C@]3(C(=C2O)C(=O)C=4C(C3=C)=C(Cl)C=CC4O)[H])[H].C(O)(=O)C1=CC(S(=O)(=O)O)=CC=C1O

Sinónimos:

• (4S,4aR,5S,5aR,12aS)-7-Chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methylene-1,11-dioxo-2-naphthacenecarboxamide mono(5-sulfosalicylate) (salt)
• 2-Naphthacenecarboxamide, 7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methylene-1,11-dioxo-, (4S,4aR,5S,5aR,12aS)-, mono(2-hydroxy-5-sulfobenzoate) (salt)
• 2-Naphthacenecarboxamide, 7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methylene-1,11-dioxo-, (4S-(4alpha,4aalpha,5alpha,5aalpha,12aalpha))-, mono(2-hydroxy-5-sulfobenzoate) (salt)
• 2-Naphthacenecarboxamide, 7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methylene-1,11-dioxo-, [4S-(4α,4aα,5α,5aα,12aα)]-, mono(2-hydroxy-5-sulfobenzoate) (salt)
• 2-hydroxy-5-sulfobenzoic acid - (2Z,4S,4aR,5S,5aR,12aS)-2-[amino(hydroxy)methylidene]-7-chloro-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methylidene-4a,5a,6,12a-tetrahydrotetracene-1,3,12(2H,4H,5H)-trione (1:1)
• Benzoic acid, 2-hydroxy-5-sulfo-, compd. with (4S,4aR,5S,5aR,12aS)-7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methylene-1,11-dioxo-2-naphthacenecarboxamide (1:1)
• Benzoic acid, 2-hydroxy-5-sulfo-, compd. with (4S-(4alpha,4aalpha,5alpha,5aalpha,12aalpha))-7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methylene-1,11-dioxo-2-naphthacenecarboxamide (1:1)
• Benzoic acid, 2-hydroxy-5-sulfo-, compd. with [4S-(4α,4aα,5α,5aα,12aα)]-7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methylene-1,11-dioxo-2-naphthacenecarboxamide (1:1)
• Meclan
• Meclan Cream
• Meclocycline 5-sulfosalicylate
• Meclocycline sulfosalicylate [USAN]
• Mecloderm
• Meclosorb
• Meclutin
• Salicylic acid, 5-sulfo-, compd. with 7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methylene-1,11-dioxo-2-naphthacenecarboxamide
• Traumatociclina
• Unii-46Vza7Rx2B
• Meclocycline sulfosalicylate
• Einecs 277-614-2
• (4S,4aR,5S,12aS)-7-chloro-4-(diMethylaMino)-3,5,10,12,12a-pentahydroxy-6-Methylene-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxaMide 2-hydroxy-5-sulfobenzoate
• FYSVKUUNXYGFLA-CCHMMTNSSA-N
• Meclocycline Sulfosalicylate (300 mg)
• MECLOCYCLINE SULFOSALICYLATE SALT
• MECLOCYLINESULFOSALICYLATE

Meclocycline sulfosalicylate salt

CAS: 73816-42-9

Fórmula: C₂₉H₂₇ClN₂O₁₄S

Pureza: 95%

Cor e Forma: Solid

Peso molecular: 695.0477

Ref: IN-DA008Q0H

Meclocycline sulfosalicylate salt

CAS: 73816-42-9

Meclocycline sulfosalicylate salt (Mecloderm) is a tetracycline antibiotic with broad-spectrum antimicrobial activity that prevents bacterial skin infections.

Fórmula: C₂₂H₂₁ClN₂O₈·C₇H₆O₆S

Pureza: 95.53% - 99.07%

Cor e Forma: Crystals

Peso molecular: 695.05

Ref: TM-T0281

Meclocycline sulfosalicylate salt

CAS: 73816-42-9

Fórmula: C₂₂H₂₁ClN₂O₈·C₇H₆O₆S

Peso molecular: 695.05

Ref: 7W-GA5097

Meclocycline sulfosalicylate salt

CAS: 73816-42-9

Meclocycline sulfosalicylate salt

Pureza: ≥95%

Peso molecular: 695.05g/mol

Ref: 54-BUP06877

Meclocycline Sulfosalicylate Salt

CAS: 73816-42-9

Meclocycline Sulfosalicylate Salt

Pureza: 98%

Peso molecular: 695.05g/mol

Ref: 54-OR1023143

Meclocycline Sulfosalicylate Salt

Produto Controlado

CAS: 73816-42-9

Stability Hygroscopic
Applications Meclocycline is a tetracycline antibiotic that is topically used for skin infections and irritations.
References Gohil, V.M., et al.: Nature. Biotechol., 28, 249 (2010); Paemen, L., et al.: Biochem. Pharmacol., 52, 105 (1996);

Fórmula: C₂₂H₂₁ClN₂O₈·C₇H₆O₆S

Cor e Forma: Neat

Peso molecular: 695.05

Ref: TR-M202720

Meclocycline sulfosalicylate

CAS: 73816-42-9

Meclocycline sulfosalicylate salt is a research chemical with various characteristics and applications. It is commonly used in laboratory settings for its unique properties. Meclocycline sulfosalicylate salt has been found to have bioavailability advantages, making it an ideal compound for certain experiments and studies. Additionally, it has been shown to interact with various substances such as zolmitriptan, glycidyl methacrylate, benzoate, trifluoromethanesulfonate, interferon, adenine, aldehyde, cellulose, inositol, strontium chloride, and fatty acids. These interactions may contribute to its efficacy in specific research contexts. Overall, meclocycline sulfosalicylate salt is a valuable tool for scientists and researchers looking to explore different areas of study.

Fórmula: C₂₂H₂₁ClN₂O₈•C₇H₆O₆S

Pureza: Min. 95%

Peso molecular: 695.05 g/mol

Ref: 3D-YCA81642

Meclocycline Sulfosalicylate

CAS: 73816-42-9

Fórmula: C₂₂H₂₁ClN₂O₈C₇H₆O₆S

Peso molecular: 476.87 : 218.18

Ref: ST-EA-CP-M120001

Meclocycline Sulfosalicylate (DISCONTINUED)

CAS: 73816-42-9

Tetracyclines and their derivatives; salts thereof

Fórmula: C₂₂H₂₁ClN₂O₈·C₇H₆O₆S

Cor e Forma: Light Yellow Powder

Peso molecular: 694.08715

Ref: 45-1377508