CAS 747-36-4

Sulfato de hidroxicloroquina

Descrição:

Sulfato de hidroxicloroquina é um medicamento antimalárico e imunomodulador usado principalmente para tratar malária, artrite reumatoide e lúpus eritematoso. É um derivado da cloroquina e funciona interferindo no crescimento de parasitas nas células vermelhas do sangue. O composto é caracterizado por sua capacidade de inibir a atividade lisossomal dentro das células, o que é crucial para a sobrevivência de certos patógenos. Sulfato de hidroxicloroquina é tipicamente administrado por via oral e é conhecido por seu perfil de toxicidade relativamente baixo em comparação com outros antimaláricos. Sua estrutura química inclui um grupo 4-aminoquinolina, que é essencial para sua atividade farmacológica. A forma de sal sulfato melhora sua solubilidade e estabilidade. Efeitos colaterais comuns podem incluir distúrbios gastrointestinais, reações cutâneas e, em casos raros, toxicidade retinal com uso prolongado. Devido aos seus efeitos imunomoduladores, a hidroxicloroquina ganhou atenção em vários usos off-label, particularmente em doenças autoimunes. No entanto, sua eficácia e segurança nesses contextos continuam sendo objeto de pesquisa e avaliação clínica em andamento.

Fórmula: C₁₈H₂₆ClN₃O·H₂O₄S

InChI: InChI=1S/C18H26ClN3O.H2O4S/c1-3-22(11-12-23)10-4-5-14(2)21-17-8-9-20-18-13-15(19)6-7-16(17)18;1-5(2,3)4/h6-9,13-14,23H,3-5,10-12H2,1-2H3,(H,20,21);(H2,1,2,3,4)

Chave InChI: InChIKey=JCBIVZZPXRZKTI-UHFFFAOYSA-N

SMILES: S(=O)(=O)(O)O.N(C(CCCN(CCO)CC)C)C=1C2=C(N=CC1)C=C(Cl)C=C2

Sinónimos:

• 2-((4-((7-Chloro-4-quinolyl)amino)pentyl)ethylamino)ethanol sulfate
• 2-([4-[(7-Chloroquinolin-4-yl)amino]pentyl](ethyl)amino)ethan-1-ol; sulfuric acid
• 7-Chloro-4-[4-N-ethyl-N-beta-hydroxyethylamino-1-methylbutylamino]quinoline sulfate
• 7-Chloro-4-[4-[ethyl(2-hydroxyethyl)amino]-1-methylbutylamino]-quinoline sulfate
• 7-chloro-4-({(1R)-4-[ethyl(2-hydroxyethyl)ammonio]-1-methylbutyl}amino)quinolinium
• 7-chloro-4-({(1S)-4-[ethyl(2-hydroxyethyl)ammonio]-1-methylbutyl}amino)quinolinium
• Ercoquin
• Ethanol, 2-[[4-[(7-chloro-4-quinolinyl)amino]pentyl]ethylamino]-, sulfate (1:1)
• Ethanol, 2-[[4-[(7-chloro-4-quinolinyl)amino]pentyl]ethylamino]-, sulfate (1:1) (salt)
• Ethanol, 2-[[4-[(7-chloro-4-quinolyl)amino]pentyl]ethylamino]-, sulfate (1:1) (salt)
• Hydrochloroquine Sulfate
• Hydroxy chloroquine sulfate
• Hydroxychloroquine sulfate
• NSC 4375
• Plaquenil
• Plaquenil sulfate
• Quensyl

Hydroxychloroquine Sulfate

CAS: 118-42-3, 747-36-4

Fórmula: C₁₈H₂₆ClN₃O·H₂SO₄

Pureza: >98.0%(HPLC)(N)

Cor e Forma: White to Light yellow powder to crystal

Peso molecular: 433.95

Ref: 3B-H1306

Hydroxychloroquine Sulphate 1.0 mg/ml in Methanol (as free base)

CAS: 747-36-4

Cor e Forma: Single Solution

Ref: 61-AMP0764.00-01

Hydroxychloroquine Sulphate

CAS: 747-36-4

Cor e Forma: Neat

Ref: 61-FOR0764.00

HYDROXYCHLOROQUINE SULFATE CRS

CAS: 747-36-4

HYDROXYCHLOROQUINE SULFATE CRS

Fórmula: C₁₈H₂₈ClN₃O₅S

Cor e Forma: Modified

Peso molecular: 433.95

Ref: 41-Y0001839

Hydroxychloroquine sulfate

CAS: 747-36-4

Hydroxychloroquine sulfate

Fórmula: C₁₈H₂₆CIN₃OH₂SO₄

Pureza: 99.7%

Cor e Forma: White. To. Off-White

Peso molecular: 537.07944

Ref: 47-1100

HYDROXYCHLOROQUINE FOR SYSTEM SUITABILITY CRS

CAS: 747-36-4

HYDROXYCHLOROQUINE FOR SYSTEM SUITABILITY CRS

Fórmula: C₁₈H₂₈ClN₃O₅S

Cor e Forma: White. Whitish. Crystalline Powder.

Peso molecular: 433.95

Ref: 41-Y0001841

Hydroxychloroquine Sulfate

CAS: 747-36-4

Drugs containing a quinoline or isoquinoline ring-system (whether or not hydrogenated) not further fused

Fórmula: C₁₈H₂₆ClN₃O·H₂O₄S

Cor e Forma: White Off-White Crystalline Powder

Peso molecular: 433.14382

Ref: 45-1327000

Hydroxychloroquine sulfate

CAS: 747-36-4

Fórmula: C₁₈H₂₈ClN₃O₅S

Pureza: 99%

Cor e Forma: Solid

Peso molecular: 433.9500

Ref: IN-DA0059P3

Hydroxychloroquine sulfate

CAS: 747-36-4

Hydroxychloroquine sulfate (Acidum iopanoicum) inhibits plasmodial heme polymerase.

Fórmula: C₁₈H₂₆ClN₃O·H₂SO₄

Pureza: 98.92% - 99.88%

Cor e Forma: Odorless Solid

Peso molecular: 433.95

Ref: TM-T0951

Hydroxychloroquine sulfate

CAS: 747-36-4

Hydroxychloroquine sulfate

Pureza: ≥98%

Peso molecular: 433.95g/mol

Ref: 54-BUP16035

Hydroxychloroquine sulfate

CAS: 747-36-4

Fórmula: C₁₈H₂₆ClN₃O·H₂SO₄

Pureza: ≥ 98.0%

Cor e Forma: White to off-white crystalline powder

Peso molecular: 433.95

Ref: 7W-GK2606

Hydroxychloroquine Sulfate

CAS: 747-36-4

Fórmula: C₁₈H₂₆ClN₃O·H₂O₄S

Cor e Forma: White To Off-White Solid

Peso molecular: 335.88 98.07

Ref: 4Z-H-061

Hydroxychloroquine Sulphate

CAS: 747-36-4

Cor e Forma: Neat

Ref: 86-MM0764.00

Hydroxychloroquine sulfate

CAS: 747-36-4

Hydroxychloroquine sulfate

Fórmula: C₁₈H₂₆ClN₃O·H₂SO₄

Pureza: 99%

Cor e Forma: white solid

Peso molecular: 433.95g/mol

Ref: 54-BISN0145

Hydroxychloroquine Sulfate

Produto Controlado

CAS: 747-36-4

Fórmula: C₁₈H₂₆ClN₃O·H₂O₄S

Cor e Forma: Neat

Peso molecular: 433.95

Ref: TR-H916900

Hydroxychloroquine Sulfate

CAS: 747-36-4

Fórmula: C₁₈H₂₆ClN₃OH₂SO₄

Peso molecular: 335.9 : 98.1

Ref: ST-EA-CP-H4012

Hydroxychloroquine sulfate

CAS: 747-36-4

Hydroxychloroquine is a 4-aminoquinolone that is used to prevent and treat malaria, caused by parasitic protozoan from the Plasmodium genus. Hydroxychloroquine is also used to treat non-infectious diseases such as rheumatoid arthritis and lupus thanks to its immunomodulatory properties. Recent studies revealed that hydroxychloroquine has beneficial effects on COVID-19 patients, as the current evidence shows that hydroxychloroquine inhibits SARS CoV-2 entry in host cells by interfering with endocytosis and affecting the glycoprofile on the spike glycoprotein.

Fórmula: C₁₈H₂₆ClN₃O•H₂SO₄

Pureza: Min. 95%

Cor e Forma: White Powder

Peso molecular: 433.95 g/mol

Ref: 3D-FH24322

Hydroxychloroquine sulfate - Bio-X ™

CAS: 747-36-4

Hydroxychloroquine is a drug that is used to treat multiple types of autoimmune diseases, including rheumatoid arthritis, systemic lupus erythematosus and discoid lupus. It is a prodrug, which is activated in the liver to hydroxychloroquine. It inhibits the production of inflammatory cytokines and nitric oxide by binding to the toll-like receptor 4 (TLR4) and inhibiting signaling pathways downstream of TLR4 activation. Additionally, Hydroxychloroquine is used to prevent and treat malaria caused by parasitic protozoan from the Plasmodium genus. Furthermore, recent studies revealed that hydroxychloroquine has beneficial effects on COVID-19 patients, as the current evidence shows that hydroxychloroquine inhibits SARS CoV-2 entry in host cells by interfering with endocytosis and affecting the glycoprofile on the spike glycoprotein.

Fórmula: C₁₈H₂₈ClN₃O₅S

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 433.95 g/mol

Ref: 3D-BH164525

2-((4-((7-Chloroquinolin-4-yl)amino)pentyl)(ethyl)amino)ethanol sulfate

CAS: 747-36-4

Fórmula: C₁₈H₂₈ClN₃O₅S

Pureza: 95.0%

Cor e Forma: Solid, White to slightly pale yellow powder

Peso molecular: 433.95

Ref: 10-F079411