CAS 74936-72-4

2,6-Dimetil-4-(3-nitrofenil)-1,4-diidropiridina-3,5-dicarboxílico ácido monometil éster

Descrição:

2,6-Dimetil-4-(3-nitrofenil)-1,4-diidropiridina-3,5-dicarboxílico ácido monometil éster é um composto orgânico complexo caracterizado por seu núcleo de dihidropiridina, que é um anel de cinco membros contendo nitrogênio. Este composto apresenta dois grupos metila nas posições 2 e 6, aumentando sua lipofilicidade e potencialmente influenciando sua atividade biológica. A presença de um grupo nitrofenila na posição 4 introduz um grupo nitro que atrai elétrons, o que pode afetar a reatividade do composto e sua interação com alvos biológicos. Além disso, o composto contém duas funcionalidades de ácido carboxílico, que estão esterificadas com um grupo metila, indicando que pode participar de várias reações químicas, incluindo hidrólise e esterificação. As características estruturais sugerem aplicações potenciais em química medicinal, particularmente no desenvolvimento de bloqueadores de canais de cálcio ou outros agentes farmacológicos. Sua estrutura molecular e grupos funcionais também podem contribuir para sua solubilidade e estabilidade em diferentes solventes, tornando-o um assunto de interesse tanto em química sintética quanto medicinal.

Fórmula: C₁₆H₁₆N₂O₆

InChI: InChI=1S/C16H16N2O6/c1-8-12(15(19)20)14(13(9(2)17-8)16(21)24-3)10-5-4-6-11(7-10)18(22)23/h4-7,14,17H,1-3H3,(H,19,20)

Chave InChI: InChIKey=JPXPPUOCSLMCHK-UHFFFAOYSA-N

SMILES: C(OC)(=O)C=1C(C(C(O)=O)=C(C)NC1C)C2=CC(N(=O)=O)=CC=C2

Sinónimos:

• (±)-1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid monomethyl ester
• (±)-1,4-Dihydro-5-methoxycarbonyl-2,6-dimethyl-4-(3-nitrophenyl)-3-pyridinecarboxylic acid
• 1,4-Dhpcooh
• 1,4-Dihydro-2,6-Dimethyl-4-(3-Nitrophenyl)-3,5-Pyridinedicarboxylic Acid 3-Methyl Ester
• 1,4-Dihydro-2,6-Dimethyl-4-(3-Nitrophenyl)-3,5-Pyridinedicarboxylic Acid,Monomethylester
• 1,4-Dihydro-2,6-Dimethyl-4-(3-Ntirophenyl)-3,5-Pyridinedicarboxylic Acid Monomet
• 2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid monomethyl ester
• 2,6-Dimethyl-5-Methoxycarbonyl-4-(3-Nitrophenyl)-1,4-Dihydordropyridine-3-Carboxylic Acid
• 2,6-Dimethyl-5-methoxycarbonyl-4-(3-nitrophenyl)-1,4-Dihydropyridine-3-carboxylic Acid
• 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-methyl ester
• 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, monomethyl ester
• 5-(Methoxycarbonyl)-2,6-Dimethyl-4-(3-Nitrophenyl)-1,4-Dihydropyridine-3-Carboxylic Acid
• 5-Methoxycarbonyl-2,6-Dimethyl-4-(3-Nitrophenyl)-1,4-Dihydrpyridine-3-Carboxylic Acid
• Lercanidipine mainring

Monomethyl 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate

CAS: 74936-72-4

Fórmula: C₁₆H₁₆N₂O₆

Pureza: >98.0%(T)(HPLC)

Cor e Forma: White to Light yellow powder to crystal

Peso molecular: 332.31

Ref: 3B-M2493

5-(Methoxycarbonyl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylic acid

CAS: 74936-72-4

Fórmula: C₁₆H₁₆N₂O₆

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 332.3080

Ref: IN-DA003M7P

2,6-Dimethyl-5-(methoxycarbonyl)-4-(3-nitrophenyl)-1,4-dihydroxypyridine-3-carboxylic acid

CAS: 74936-72-4

2,6-Dimethyl-5-(methoxycarbonyl)-4-(3-nitrophenyl)-1,4-dihydroxypyridine-3-carboxylic acid

Pureza: 98%

Peso molecular: 364.31g/mol

Ref: 54-OR315749

Lercanidipine EP Impurity A

CAS: 74936-72-4

Fórmula: C₁₆H₁₆N₂O₆

Peso molecular: 332.31

Ref: 4Z-L-17116

1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylic Acid Methyl Ester

CAS: 74936-72-4

Cor e Forma: Neat

Ref: 86-MM0092.04

Nicardipine USP Related Compound A

CAS: 74936-72-4

Fórmula: C₁₆H₁₆N₂O₆

Peso molecular: 332.31

Ref: ST-EA-CP-N7003

Lercanidipine EP Impurity A

CAS: 74936-72-4

Fórmula: C₁₆H₁₆N₂O₆

Peso molecular: 332.31

Ref: ST-EA-CP-L36001

1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 3-Methyl Ester

CAS: 74936-72-4

Impurity Nicardipine USP Related Compound A
Applications 1,4-Dihydropyridine derivative used in the prevention and therapy of atherosclerotic degradation of arterial walls. Nicardipine USP Related Compound A.
References Henry, P.D., et al.: Clin. Invest. Med., 10, 601 (1987), Weinstein, D.B., et al.: Am. J. Med., 86, 27 (1989), Gaviraghi, G., et al.: Pharmacol. Res., 31, 251 (1995),

Fórmula: C₁₆H₁₆N₂O₆

Cor e Forma: Light Yellow

Peso molecular: 332.31

Ref: TR-D449123

5-(Methoxycarbonyl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylic acid

CAS: 74936-72-4

Fórmula: C₁₆H₁₆N₂O₆

Pureza: ≥98%

Cor e Forma: Solid, White - Slightly pale yellow powder

Peso molecular: 332.312

Ref: 10-F213474

1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 3-Methyl Ester-d3

Produto Controlado

CAS: 74936-72-4

Fórmula: C₁₆D₃H₁₃N₂O₆

Cor e Forma: Neat

Peso molecular: 335.327

Ref: TR-D449124

1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 3-methyl ester

CAS: 74936-72-4

Lercanidipine is a calcium antagonist that binds to the calcium channels in the membranes of cells, preventing the entry of calcium ions. Lercanidipine is water soluble and can be synthesized using techniques such as elemental analysis and pharmacological techniques. It is also an ionizable drug, which means that its affinity for chloride varies with pH. Lercanidipine has been shown to have strong affinity for erythrocyte membranes and thus has a high selectivity for vascular smooth muscle cells. This drug also has a low toxicity profile and does not affect tissues other than vascular smooth muscle cells.

Fórmula: C₁₆H₁₆N₂O₆

Pureza: Min. 95%

Cor e Forma: White Powder

Peso molecular: 332.31 g/mol

Ref: 3D-FD21967

Nicardipine Impurity 44

CAS: 74936-72-4

Fórmula: C₁₆H₁₆N₂O₆

Cor e Forma: Pale Yellow Solid

Peso molecular: 332.31

Ref: 4Z-N-489