CAS 75539-79-6

N-cbz-D-phe-phe-gly

Descrição:

N-cbz-D-phe-phe-gly, também conhecido pelo seu número CAS 75539-79-6, é um peptídeo sintético que apresenta uma combinação de aminoácidos, especificamente fenilalanina (Phe) e glicina (Gly), com um grupo protetor carbobenzyloxi (Cbz) no resíduo de D-fenilalanina. Este composto é caracterizado por sua forma sólida branca a off-white e é solúvel em solventes orgânicos como dimetilsulfóxido (DMSO) e metanol, mas geralmente insolúvel em água. A presença do grupo Cbz proporciona estabilidade e protege o grupo amino durante a síntese de peptídeos, tornando-o útil em várias aplicações bioquímicas, incluindo síntese de peptídeos e desenvolvimento de medicamentos. A estereoquímica da D-fenilalanina é significativa, pois pode influenciar a atividade biológica e as interações do peptídeo. N-cbz-D-phe-phe-gly pode ser utilizado em ambientes de pesquisa, particularmente em estudos relacionados ao comportamento de peptídeos, ligação a receptores e desenvolvimento de agentes terapêuticos. As condições adequadas de manuseio e armazenamento são essenciais para manter sua integridade e eficácia em aplicações experimentais.

Fórmula: C₂₈H₂₉N₃O₆

InChI: InChI=1/C28H29N3O6/c32-25(33)18-29-26(34)23(16-20-10-4-1-5-11-20)30-27(35)24(17-21-12-6-2-7-13-21)31-28(36)37-19-22-14-8-3-9-15-22/h1-15,23-24H,16-19H2,(H,29,34)(H,30,35)(H,31,36)(H,32,33)/t23-,24+/m0/s1

Sinónimos:

• Z-D-Phe-Phe-Gly-OH
• N-[(benzyloxy)carbonyl]-D-phenylalanyl-L-phenylalanylglycine

Z-D-Phe-Phe-Gly-OH

CAS: 75539-79-6

A high level of inhibition of virus replication was obtained with this peptide, which resembles a region of a viral polypeptide.

Fórmula: C₂₈H₂₉N₃O₆

Pureza: > 99%

Cor e Forma: White Powder

Peso molecular: 503.56

Ref: 01-4015768

Virus Replication Inhibiting Peptide

CAS: 75539-79-6

The virus replication-inhibiting peptide is a fatty acid that inhibits the replication of viruses. It has been shown to inhibit the growth of the bacteria Stenotrophomonas maltophilia and other bacteria, which causes infectious diseases. The peptide also has a diagnostic use for detecting viral infections in cells. The peptide was found to up-regulate genes in response to infection by pandemic influenza, which may be due to its ability to bind receptors on cells and also interfere with inflammatory responses. The virus replication-inhibiting peptide has been shown to be effective against influenza virus and other viruses, as well as against chronic inflammatory diseases such as lung damage caused by β-amino acids.

Fórmula: C₂₈H₂₉N₃O₆

Pureza: Min. 95%

Peso molecular: 503.55 g/mol

Ref: 3D-PVI-4092

Z-D-Phe-Phe-Gly-OH

CAS: 75539-79-6

Z-D-Phe-Phe-Gly-OH is a lysosomal carboxypeptidase that hydrolyzes peptides at the C terminus of proteins. It has a wide substrate specificity and can hydrolyze Z-D-Phe-Phe-Gly, Z-Arg-Lys, and L-Arg. This enzyme has been shown to have ion exchange chromatography activity. The elution profile for this enzyme on a sephadex G-100 column was found to have an optimum pH of 7.5 and elutes at a salt concentration of 0.5M NaCl. Carboxypeptidases are enzymes that cleave at the C terminus of proteins to produce smaller peptides or amino acids. They are involved in digestion, blood clotting, and cell signaling processes.

Fórmula: C₂₈H₂₉N₃O₆

Pureza: Min. 95%

Cor e Forma: White Off-White Powder

Peso molecular: 503.55 g/mol

Ref: 3D-FP110429