CAS 762240-92-6

Cloridrato de 3-(trifluorometil)-5,6,7,8-tetrahidro-[1,2,4]triazolo[4,3-a]pirazina

Descrição:

Cloridrato de 3-(trifluorometil)-5,6,7,8-tetrahidro-[1,2,4]triazolo[4,3-a]pirazina é um composto químico caracterizado por sua estrutura bicíclica única, que incorpora tanto moieties de triazol quanto de pirazina. A presença de um grupo trifluorometílico aumenta sua lipofilicidade e pode influenciar sua atividade biológica. Este composto é tipicamente encontrado como um sal de cloridrato, o que melhora sua solubilidade em ambientes aquosos, tornando-o adequado para várias aplicações, incluindo pesquisa farmacêutica. A configuração de tetrahidro indica que o composto é saturado, contribuindo para sua estabilidade e potencialmente afetando sua reatividade. Sua estrutura molecular sugere interações potenciais com alvos biológicos, tornando-o de interesse em química medicinal. O número CAS do composto, 762240-92-6, permite a identificação precisa e recuperação de informações em bancos de dados químicos. No geral, esta substância exemplifica a complexidade e diversidade dos compostos heterocíclicos, com implicações para o desenvolvimento de medicamentos e outras aplicações químicas.

Fórmula: C₆H₇F₃N₄·ClH

InChI: InChI=1S/C6H7F3N4.ClH/c7-6(8,9)5-12-11-4-3-10-1-2-13(4)5;/h10H,1-3H2;1H

Chave InChI: InChIKey=AQCSCRYRCRORET-UHFFFAOYSA-N

SMILES: C(F)(F)(F)C=1N2C(=NN1)CNCC2.Cl

Sinónimos:

• 1,2,4-Triazolo[4,3-a]pyrazine, 5,6,7,8-tetrahydro-3-(trifluoromethyl)-, hydrochloride (1:1)
• 1,2,4-Triazolo[4,3-a]pyrazine, 5,6,7,8-tetrahydro-3-(trifluoromethyl)-, monohydrochloride
• 3-(Trifluoromethyl)-5,6,7,8-Retrahydro-[1,2,4]Triazolo[4,3-A]Pyrazine Hydrochloride
• 3-(Trifluoromethyl)-5,6,7,8-Tetrahydro-1,2,4-Triazolo-[4,3-Alpha] Pyrazine Hydrochloride
• 3-(Trifluoromethyl)-5,6,7,8-Tetrahydro-[1,2,4]Traazoli[4,3-1]Pyrazine Hydrochloride
• 3-(Trifluoromethyl)-5,6,7,8-Tetrahydro[1,2,4]Triazolo[4,3-A]Pyrazine
• 3-(Trifluoromethyl)-5,6,7,8-Tetrahydro[1,2,4]Triazolo[4,3-A]Pyrazine Hydrochloride (1:1)
• 3-(Trifluoromethyl)-5,6,7,8-tetrahydro-(1,2,4)trazolo(4,3-a)pyrazine hydrochloride
• 3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine Hcl
• 3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride
• 3-(Trifluoromethyl)-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyrazine monohydrochloride
• 3-(trifluoromethyl)-5H,6H,7H,8H-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride
• IntermediateⅠof Sitagliptin phosphate
• Sitagliptin Intermediate
• Tap-4

3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine Hydrochloride

CAS: 762240-92-6

Fórmula: C₆H₇F₃N₄·HCl

Pureza: >98.0%(HPLC)

Cor e Forma: White to Light yellow powder to crystal

Peso molecular: 228.60

Ref: 3B-T2998

3-(Trifluoromethyl)-5,6,7,8-tetrahydro-1,2,4-triazolo[4,3-a]pyrazine hydrochloride, 98+%

CAS: 762240-92-6

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Fórmula: C₆H₈ClF₃N₄

Pureza: 98+%

Peso molecular: 228.60

Ref: 02-H64993

3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine, HCl

CAS: 762240-92-6

Fórmula: C₆H₈ClF₃N₄

Pureza: 97%

Cor e Forma: Solid

Peso molecular: 228.6027

Ref: IN-DA0033H6

Sitagliptin Impurity 20 HCl

CAS: 762240-92-6

Fórmula: C₆H₇F₃N₄·HCl

Cor e Forma: White To Off-White Solid

Peso molecular: 192.15 36.46

Ref: 4Z-S-2013

Sitagliptin Intermediate 2

CAS: 762240-92-6

Sitagliptin Intermediate 2

Pureza: ≥95%

Peso molecular: 228.603g/mol

Ref: 54-BUP19491

3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine Hydrochloride

CAS: 762240-92-6

Cor e Forma: Neat

Ref: 86-MM3378.04

Sitagliptin Intermediate 2

CAS: 762240-92-6

Sitagliptin Intermediate 2 is a useful organic compound that has been used in life science related research.

Fórmula: C₆H₈ClF₃N₄

Pureza: 98%

Cor e Forma: Yellow-Brown Solid Crystalline

Peso molecular: 228.603

Ref: TM-T5903

5,6,7,8-Tetrahydro-3-(trifluoromethyl)[1,2,4]triazolo[4,3-a]pyrazine hydrochloride

CAS: 762240-92-6

5,6,7,8-Tetrahydro-3-(trifluoromethyl)[1,2,4]triazolo[4,3-a]pyrazine hydrochloride

Fórmula: C₆H₇F₃N₄·ClH

Pureza: 98%

Cor e Forma: white to off-white solid

Peso molecular: 228.60g/mol

Ref: 54-PC51048

3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine-d4 Hydrochloride

Produto Controlado

CAS: 762240-92-6

Applications Isotope labelled Sitagliptin (S491000) intermediate.
References Mohri, K., et al.: Chem. Pharm. Bull., 30, 3097 (1982) , Sarges, R., et al.: J. Med. Chem., 33, 2240 (1990), Cameron, M., et al.: J. Pharm. Biomed. Anal., 28, 137 (2002),

Fórmula: C₆H₃D₄F₃N₄·x(HCl)

Cor e Forma: Neat

Peso molecular: 196.17 + x(36.46)

Ref: TR-T791812

Sitagliptin Triazole Hydrochloride

CAS: 762240-92-6

Fórmula: C₆H₇F₃N₄HCl

Peso molecular: 192.15 : 36.46

Ref: ST-EA-CP-S3004

3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride

CAS: 762240-92-6

Inhibitor of DDP-4 peptidase

Fórmula: C₆H₇F₃N₄•HCl

Pureza: Min. 98 Area-%

Cor e Forma: White Powder

Peso molecular: 228.6 g/mol

Ref: 3D-FT44582

3-Trifluoromethyl-5,6,7,8-tetrahydro-1,2,4-triazolo-[4,3-a]pyrazine hydrochloride

CAS: 762240-92-6

Fórmula: C₆H₈ClF₃N₄

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 228.6

Ref: 10-F076905

3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine Hydrochloride

CAS: 762240-92-6

Applications Sitagliptin intermediate.
References Mohri, K., et al.: Chem. Pharm. Bull., 30, 3097 (1982), Sarges, R., et al.: J. Med. Chem., 33, 2240 (1990), Cameron, M., et al.: J. Pharm. Biomed. Anal., 28, 137 (2002),

Fórmula: C₆H₇F₃N₄·ClH

Cor e Forma: White

Peso molecular: 228.60

Ref: TR-T791810