CAS 76330-71-7

Altanserina

Descrição:

Altanserina é um composto químico reconhecido principalmente por seu papel como antagonista seletivo do receptor de serotonina 5-HT2A. É frequentemente utilizado em pesquisas farmacológicas, particularmente em estudos relacionados à neurofarmacologia e à investigação de transtornos psiquiátricos. O composto possui uma estrutura molecular complexa, que contribui para sua afinidade de ligação específica ao receptor 5-HT2A, tornando-o uma ferramenta valiosa para entender as vias relacionadas à serotonina no cérebro. Altanserina é tipicamente caracterizado por sua lipofilicidade moderada, que influencia sua biodisponibilidade e distribuição dentro dos sistemas biológicos. Além disso, é conhecido por suas potenciais aplicações em estudos de imagem, particularmente em tomografia por emissão de pósitrons (PET) para visualizar a atividade do receptor de serotonina. Perfis de segurança e toxicidade são considerações essenciais em seu uso, assim como em qualquer agente farmacológico. No geral, Altanserina serve como um composto importante tanto em contextos terapêuticos quanto de pesquisa, auxiliando na exploração do papel da serotonina em várias condições neurológicas e psiquiátricas.

Fórmula: C₂₂H₂₂FN₃O₂S

InChI: InChI=1S/C22H22FN3O2S/c23-17-7-5-15(6-8-17)20(27)16-9-11-25(12-10-16)13-14-26-21(28)18-3-1-2-4-19(18)24-22(26)29/h1-8,16H,9-14H2,(H,24,29)

Chave InChI: InChIKey=SMYALUSCZJXWHG-UHFFFAOYSA-N

SMILES: O=C1C=2C(NC(=S)N1CCN3CCC(C(=O)C4=CC=C(F)C=C4)CC3)=CC=CC2

Sinónimos:

• 278-422-1
• 3-(2-{4-[(4-fluorophenyl)carbonyl]piperidin-1-yl}ethyl)-2-thioxo-2,3-dihydroquinazolin-4(1H)-one
• 3-[2-[4-(4-Fluorobenzoyl)-1-piperidinyl]ethyl]-2,3-dihydro-2-thioxo-4(1H)-quinazolinone
• 3-{2-[4-(4-Fluorobenzoyl)piperidin-1-yl]ethyl}-2-thioxo-2,3-dihydroquinazolin-4(1H)-one
• 4(1H)-quinazolinone, 3-[2-[4-(4-fluorobenzoyl)-1-piperidinyl]ethyl]-2,3-dihydro-2-thioxo-
• 76330-71-7
• Altanserin
• Altanserin hydrochloride hydrate
• 3-(2-(4-(4-Fluorobenzoyl)-1-piperidinyl)ethyl)-2,3-dihydro-2-thioxo-4(1H)-quinazolinonehydrochloride
• 3-[2-[4-(4-Fluorobenzoyl)-1-piperidinyl]ethyl]-2,3-dihydro-2-thioxo-4(1H)-quinazolinone hydrate hydrochloride
• AltanserineHCl
• ALTANSERIN HYDROCHLORIDE
• 3-[2-[4-(4-FLUOROBENZOYL)-1-PIPERIDINYL]ETHYL]-2,3-DIHYDRO-2-THIOXO-4(1H)-QUINAZOLINONE HYDROCHLORIDE
• 3-[2-[4-(4-Fluorobenzoyl)piperidin-1-yl]ethyl]-2-sulfanylidene-1H-quinazolin-4-one
• Altanserin hydrate hydrochloride
• 3-[2-[4-(4-Fluorobenzoyl)-1-piperidinyl]ethyl]-2,3-dihydro-2-thioxo-4(1H)-quinazolinone hydrochloride hydrate

altanserin hydrochloride

CAS: 76330-71-7

Fórmula: C₂₂H₂₂FN₃O₂S

Pureza: 97%

Cor e Forma: Solid

Peso molecular: 411.4924

Ref: IN-DA0056E0

3-(2-(4-(4-Fluorobenzoyl)Piperidin-1-Yl)Ethyl)-2-Thioxo-2,3-Dihydroquinazolin-4(1H)-One

CAS: 76330-71-7

3-(2-(4-(4-Fluorobenzoyl)Piperidin-1-Yl)Ethyl)-2-Thioxo-2,3-Dihydroquinazolin-4(1H)-One

Pureza: 99%

Peso molecular: 411.49g/mol

Ref: 54-PC108570

Altanserin hydrochloride hydrate

CAS: 76330-71-7

Fórmula: C₂₂H₂₂FN₃O₂S·HCl·xH₂O

Peso molecular: 447.95 (anhydrous)

Ref: 7W-GL6252

Altanserin

CAS: 76330-71-7

Altanserin, a 5-HT2A receptor binder, is tagged with F-18 for brain PET scans.

Fórmula: C₂₂H₂₂FN₃O₂S

Cor e Forma: Solid

Peso molecular: 411.49

Ref: TM-T29913

Altanserin hydrochloride hydrate

CAS: 76330-71-7

Altanserin is a drug that binds to the 5-HT2 receptor and blocks its interactions with other molecules. Altanserin has been shown to have a synergic effect with antidepressants such as desipramine and fluoxetine, which are selective serotonin reuptake inhibitors (SSRIs). It has also been shown to inhibit the uptake of 5-HT in the brain, which may be related to its effect on locomotor activity. The use of altanserin for HIV infection is still being studied. One study found that altanserin reduced viral load and increased CD4+ T cell counts in HIV patients who were not taking any other anti-HIV drugs. A recent study found that altanserin at dosages up to 4mg/kg/day did not cause any toxic effects in rats.

Fórmula: C₂₂H₂₂FN₃O₂S•HCl•(H₂O)x

Pureza: Min. 95%

Ref: 3D-BA183187

Altanserin

Produto Controlado

CAS: 76330-71-7

Fórmula: C₂₂H₂₂FN₃O₂S

Cor e Forma: Neat

Peso molecular: 411.492

Ref: TR-A585985

Altanserin

CAS: 76330-71-7

Altanserin is a drug that binds to the 5-HT2 receptor and blocks its interactions with other molecules. Altanserin has been shown to have a synergic effect with antidepressants such as desipramine and fluoxetine, which are selective serotonin reuptake inhibitors (SSRIs). It has also been shown to inhibit the uptake of 5-HT in the brain, which may be related to its effect on locomotor activity. The use of altanserin for HIV infection is still being studied. One study found that altanserin reduced viral load and increased CD4+ T cell counts in HIV patients who were not taking any other anti-HIV drugs. A recent study found that altanserin at dosages up to 4mg/kg/day did not cause any toxic effects in rats.

Pureza: Min. 95%

Ref: 3D-FA41790