CAS 7640-51-9

10H-Fenotiazina-10-etanamina, N,N,α-trimetil-, 5-óxido

Descrição:

10H-Fenotiazina-10-etanamina, N,N,α-trimetil-, 5-óxido, comumente referido como um derivado da fenotiazina, é um composto químico caracterizado por sua estrutura de base de fenotiazina, que consiste em uma estrutura heterocíclica contendo enxofre e nitrogênio. Este composto geralmente exibe propriedades como ser um sólido à temperatura ambiente, com aplicações potenciais em farmacêuticos, particularmente como um agente antipsicótico ou antihistamínico devido à sua capacidade de interagir com sistemas de neurotransmissores. A presença do grupo trimetilamina aumenta sua solubilidade e reatividade, tornando-o útil em várias reações químicas. Além disso, a designação 5-óxido indica a presença de um átomo de nitrogênio oxidado, que pode influenciar as propriedades eletrônicas e a reatividade do composto. Sua estrutura molecular contribui para sua atividade biológica, e pode exibir fluorescência, tornando-o útil em química analítica. Dados de segurança devem ser consultados para manuseio e exposição, como com todas as substâncias químicas, para garantir que as precauções adequadas sejam tomadas.

Fórmula: C₁₇H₂₀N₂OS

InChI: InChI=1/C17H20N2OS/c1-13(18(2)3)12-19-14-8-4-6-10-16(14)21(20)17-11-7-5-9-15(17)19/h4-11,13H,12H2,1-3H3

Chave InChI: InChIKey=OWTCLFIFAFHQIX-UHFFFAOYSA-N

SMILES: C(C(N(C)C)C)N1C=2C(S(=O)C=3C1=CC=CC3)=CC=CC2

Sinónimos:

• 10-(2-(Dimethylamino)propyl)-10H-phenothiazine 5-oxide
• 10-(2-(Dimethylamino)propyl)-10H-phenothiazine5-oxide
• 10H-Phenothiazine-10-ethanamine, N,N,alpha-trimethyl-, 5-oxide
• 10H-Phenothiazine-10-ethanamine, N,N,α-trimethyl-, 5-oxide
• Diprazin sulfoxide
• N,N,alpha-Trimethyl-10H-phenothiazine-10-ethanamine 5-oxide
• N-[2-(Dimethylamino)propyl]phenothiazine S-oxide
• Phenothiazine, 10-[2-(dimethylamino)propyl]-, 5-oxide
• Promethazine 5-oxide
• Promethazine 5-sulfoxide
• Promethazine sulfoxide
• Romergan sulfoxide
• ProMethazine EP IMpurity D
• N,N,α-TriMethyl-10H-phenothiazine-10-ethanaMine 5-Oxide
• Promethazine Impurity 4(Promethazine EP Impurity D)
• N,N,a-Trimethyl-10H-phenothiazine-10-ethanamine 5-Oxide
• Promethazine Impurity 4(EP Impurity D)
• Promethazine EP Impurity D Dihydrochloride
• PROMETHAZINE EP IMPURITY D (PROMETHAZINE SULFOXIDE)
• (2RS)-N,N-Dimethyl-1-(10H-phenothiazin-10-yl)propan-2-amine S-oxide
• N,N-dimethyl-1-(5-oxophenothiazin-10-yl)propan-2-amine

Promethazine EP Impurity D

CAS: 7640-51-9

Fórmula: C₁₇H₂₀N₂OS

Peso molecular: 300.42

Ref: ST-EA-CP-P86004

Promethazine Sulphoxide 1.0 mg/ml in Methanol

CAS: 7640-51-9

Cor e Forma: Single Solution

Ref: 61-AMP0412.04-01

Promethazine sulfoxide

CAS: 7640-51-9

Promethazine sulfoxide

Fórmula: C₁₇H₂₀N₂OS

Cor e Forma: White Solid

Peso molecular: 300.4185

Ref: 47-505

PROMETHAZINE IMPURITY D CRS

CAS: 7640-51-9

PROMETHAZINE IMPURITY D CRS

Ref: 41-Y0000769

Promethazine Sulfoxide

CAS: 7640-51-9

Compounds (excluding drugs) containing a phenothiazine ring-system (whether or not hydrogenated), not further fused

Fórmula: C₁₇H₂₀N₂OS

Cor e Forma: Grey Powder

Peso molecular: 300.12963

Ref: 45-1A10030

10-(2-(Dimethylamino)propyl)-10H-phenothiazine 5-oxide

CAS: 7640-51-9

Fórmula: C₁₇H₂₀N₂OS

Pureza: 95%

Cor e Forma: Solid

Peso molecular: 300.4185

Ref: IN-DA008QHQ

Promethazine EP Impurity D (Promethazine Sulfoxide)

CAS: 7640-51-9

Fórmula: C₁₇H₂₀N₂OS

Cor e Forma: White To Off-White Solid

Peso molecular: 300.42

Ref: 4Z-P-181

10-(2-(Dimethylamino)propyl)-10H-phenothiazine 5-oxide

CAS: 7640-51-9

10-(2-(Dimethylamino)propyl)-10H-phenothiazine 5-oxide

Pureza: 95%

Peso molecular: 300.43g/mol

Ref: 54-OR1046044

Promethazine EP Impurity D

Produto Controlado

CAS: 7640-51-9

Fórmula: C₁₇H₂₀N₂OS

Cor e Forma: Neat

Peso molecular: 300.42

Ref: 86-MM0412.04

Promethazine Sulfoxide

Produto Controlado

CAS: 7640-51-9

Impurity Promethazine EP Impurity D
Applications Promethazine Sulfoxide (Promethazine EP Impurity D) is a metabolite of Promethazine (P757000).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Gottschalk, L., et al.: J. Pharm. Sci., 67, 155 (1978), de Jongh, G., et al.: Drug Metab. Dispos., 9, 48 (1981), Hale, P., et al.: Toxicol. Appl. Pharmacol., 86, 44 (1986), Delbressine, L., et al.: Xenobiotica, 22, 227 (1992),

Fórmula: C₁₇H₂₀N₂OS

Cor e Forma: Light Red To Purple

Peso molecular: 300.42

Ref: TR-P757010

Promethazine sulfoxide

CAS: 7640-51-9

Promethazine sulfoxide is a phenothiazine derivative that is used in the treatment of allergies, colds, and motion sickness. It has been shown to inhibit peroxidases and reactions involving the production of hydrogen peroxide. Promethazine sulfoxide is metabolized by two pathways: one involving oxidation by cytochrome P450 enzymes and another involving hydrolysis by esterases or glucuronidases. The main metabolites are promethazine, promethazine sulfone, and N-methylpromethazine. When applied to urine samples, promethazine sulfoxide can be detected in concentrations of 1-10 ng/mL with an analytical method based on chromatography.

Fórmula: C₁₇H₂₀N₂OS

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 300.42 g/mol

Ref: 3D-FP27184

Promethazine Sulphoxide

CAS: 7640-51-9

Cor e Forma: Neat

Ref: 61-FOR0412.04