CAS 765875-58-9
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4 produtos.
N-Deacylvaline Ritonavir (Thiazol-5-ylmethyl (2S,3S,5S)-5-[(S)-2-amino-3-methylbutanamido]-3-hydroxy-1,6-diphenylhexan-2-ylcarbamate)
CAS:Compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structureFórmula:C28H36N4O4SPeso molecular:524.24573Ritonavir EP Impurity B HCl (Monoacyl Valine HCl)
CAS:Fórmula:C28H36N4O4S·HClCor e Forma:White To Off-White SolidPeso molecular:524.68 36.46[4-[(2-Amino-3-methyl-1-oxobutyl)amino]-2-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]-carbamic Acid 5-Thiazolylmethyl Ester
CAS:Produto ControladoImpurity Ritonavir EP Impurity D
Applications [4-[(2-Amino-3-methyl-1-oxobutyl)amino]-2-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]-carbamic Acid 5-Thiazolylmethyl Ester, is an intermediate that can be used for the synthesis of Ritonavir (R535000), which is a selective HIV protease inhibitor.
References Daluge, S., et al.: Antimicrob. Agents Chemother., 38, 1590 (1994), Ammaranond, P., et al.: J. Clin. Virol., 26, 153 (2003), Harrigan, P., et al.: J. Infect. Dis., 191, 339 (2005), Miller, J., et al.: Bioorg. Med. Chem. Lett., 16, 1788(2006); Kempf, D., et al.: J. Med. Chem., 41, 602 (1998),Fórmula:C28H36N4O4SCor e Forma:NeatPeso molecular:524.68
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