CAS 76684-89-4

Ácido loxistatina

Descrição:

Ácido loxistatina, com o número CAS 76684-89-4, é um composto químico que pertence à classe das estatinas, conhecidas principalmente por seu papel em medicamentos para redução do colesterol. É caracterizado por sua capacidade de inibir a HMG-CoA redutase, uma enzima crucial na biossíntese do colesterol. Essa inibição leva a uma diminuição nos níveis de colesterol na corrente sanguínea, tornando-o benéfico para o manejo da hiperlipidemia e redução do risco de doenças cardiovasculares. Ácido loxistatina é tipicamente um sólido branco a branco sujo e é solúvel em solventes orgânicos, mas sua solubilidade em água é limitada. O composto pode apresentar várias atividades biológicas, incluindo propriedades anti-inflamatórias e antioxidantes, que contribuem para seu potencial terapêutico. Assim como muitas estatinas, pode ter efeitos colaterais, incluindo dor muscular e alterações nas enzimas hepáticas, necessitando de monitoramento durante o uso. No geral, Ácido loxistatina representa um avanço significativo na farmacologia para o manejo da saúde cardiovascular.

Fórmula: C₁₅H₂₆N₂O₅

InChI: InChI=1/C15H26N2O5/c1-8(2)5-6-16-13(18)10(7-9(3)4)17-14(19)11-12(22-11)15(20)21/h8-12H,5-7H2,1-4H3,(H,16,18)(H,17,19)(H,20,21)/t10-,11-,12-/m0/s1

Chave InChI: InChIKey=SCMSYZJDIQPSDI-SRVKXCTJSA-N

SMILES: C(N[C@H](C(NCCC(C)C)=O)CC(C)C)(=O)[C@@H]1[C@@H](C(O)=O)O1

Sinónimos:

• (+)-(2S,3S)-3-((S)-3-Methyl-1-(3-methylbutylcarbamoyl)butylcarbamoyl)-2-oxiranecarboxylic acid
• (2S,3S)-3-({(2S)-4-methyl-1-[(3-methylbutyl)amino]-1-oxopentan-2-yl}carbamoyl)oxirane-2-carboxylic acid
• (2S,3S)-3-[[[(1S)-3-Methyl-1-[[(3-methylbutyl)amino]carbonyl]butyl]amino]carbonyl]-2-oxiranecarboxylic acid
• 2-Oxiranecarboxylic acid, 3-[[[(1S)-3-methyl-1-[[(3-methylbutyl)amino]carbonyl]butyl]amino]carbonyl]-, (2S,3S)-
• Brn 6688621
• E 64c
• EP 475 (Enzyme inhibitor)
• Ep 475
• Loxistatin acid
• NSC 694279
• Oxiranecarboxylic acid, 3-(((3-methyl-1-(((3-methylbutyl)amino)carbonyl)butyl)amino)carbonyl)-, (2S-(2-alpha,3-beta(R*)))-
• Oxiranecarboxylic acid, 3-(((3-methyl-1-(((3-methylbutyl)amino)carbonyl)butyl)amino)carbonyl)-, (2S-(2alpha,3beta(R*)))-
• Oxiranecarboxylic acid, 3-[[[(1S)-3-methyl-1-[[(3-methylbutyl)amino]carbonyl]butyl]amino]carbonyl]-, (2S,3S)-
• Oxiranecarboxylic acid, 3-[[[3-methyl-1-[[(3-methylbutyl)amino]carbonyl]butyl]amino]carbonyl]-, [2S-[2α,3β(R*)]]-
• (2S,3S)-L-TRANS-EPOXYSUCCINYL-L-LEUCYLAMIDO-3-METHYLBUTANE
• (1S,2S)-2-(((S)-1-(Isopentylamino)-4-methyl-1-oxopentan-2-yl)carbamoyl)cyclopropanecarboxylic
• anecarboxylicacid
• (2S,3S)-TRANS-EPOXYSUCCINYL-L-LEUCYLAMIDO-3-METHYLBUTANE
• Loxistatin Acid (E-64C)
• (2S,3S)-3-(((S)-1-(isopentylaMino)-4-Methyl-1-oxopentan-2-yl)carbaMoyl)oxirane-2-carboxylic acid
• E-64-c Loxistatin acid NSC 694279
• (L-3-TRANS-CARBOXYOXIRANE-2-CARBONYL)-L-LEUCINE (3-METHYLBUTYL)AMIDE
• (2S,3S)-3-[[(1S)-1-(3-Methylbutylcarbamoyl)-3-methylbutyl]carbamoyl]oxirane-2-carboxylic acid
• NSC 694279 Loxistatin Acid
• NSC 694279 LOXISTATIN ACID; EP 475;E64C;E 64C
• (2s-(2-alpha,3-beta(r*)))-mino)carbonyl)
• ep475(enzymeinhibitor)
• L-TRANS-EPOXYSUCCINYL-LEU-3-METHYLBUTYLAMIDE
• (+)-(2s,3s)-3-((s)-3-methyl-1-(3-methylbutylcarbamoyl)butylcarbamoyl)-2-oxir
• (2S,3S)-TRANS-EPOXYSUCCINYL-L-*LEUCYLAMI DO-3-METHYL
• oxiranecarboxylicacid,3-(((3-methyl-1-(((3-methylbutyl)amino)carbonyl)butyl)a
• Inhibitorforthiolprotease
• 2-Oxiranecarboxylicacid,3-[[[(1S)-3-methyl-1-[[(3-methylbutyl)amino]carbonyl]butyl]amino]carbonyl]-,(2S,3S)-
• E-64c, EP 475

E-64c

CAS: 76684-89-4

Fórmula: C₁₅H₂₆N₂O₅

Pureza: 95%

Cor e Forma: Solid

Peso molecular: 314.3773

Ref: IN-DA00G359

E 64c

CAS: 76684-89-4

E 64c

Pureza: ≥98%

Peso molecular: 314.38g/mol

Ref: 54-BUP02992

E-64c Calpain Inhibitor

CAS: 76684-89-4

Fórmula: C₁₅H₂₆N₂O₅

Peso molecular: 314.38

Ref: 7W-GL8757

E-64c

CAS: 76684-89-4

E-64c

Pureza: 95%

Cor e Forma: Solid

Peso molecular: 314.38g/mol

Ref: 54-BIE1004

E 64c

CAS: 76684-89-4

E 64c (EP 475) , a derivative of E-64, is an irreversible and membrane-permeant cysteine protease inhibitor.

Fórmula: C₁₅H₂₆N₂O₅

Pureza: 98.73%

Cor e Forma: Solid

Peso molecular: 314.38

Ref: TM-T6573

(2S,3S)-3-(((S)-1-(Isopentylamino)-4-methyl-1-oxopentan-2-yl)carbamoyl)oxirane-2-carboxylic acid

CAS: 76684-89-4

Pureza: ≥98%

Peso molecular: 314.3819885

Ref: 10-F869543

E-64-c

CAS: 76684-89-4

E-64-c is a research tool that is used to activate the receptor of a cell. This ligand can bind to the receptor and form a complex, which will then be able to interact with other proteins in the cell. This process can lead to changes in ion channel activity, protein synthesis, or gene expression. E-64-c has been shown to inhibit the activity of ion channels such as calcium channels and potassium channels, as well as protein synthesis. It also binds to antibodies and blocks their binding sites on cells.br>
E-64-c is a high purity ligand that can be used for studying protein interactions or pharmacological purposes. The potency of this ligand has been tested by measuring its ability to inhibit the binding of various peptides such as vasopressin and angiotensin II.

Fórmula: C₁₅H₂₆N₂O₅

Pureza: Min. 95%

Peso molecular: 314.38 g/mol

Ref: 3D-IEC-4320-V