CAS 769-42-6

Ácido dimetilbarbitúrico

Descrição:

Ácido dimetilbarbitúrico, com o número CAS 769-42-6, é um composto químico que pertence à classe de drogas barbitúricas, que são derivados do ácido barbitúrico. É caracterizado por sua estrutura, que inclui dois grupos metila ligados aos átomos de nitrogênio da estrutura do ácido barbitúrico. Este composto é tipicamente um sólido cristalino branco que é solúvel em água e exibe propriedades fracamente ácidas devido à presença de grupos funcionais de ácido carboxílico. Ácido dimetilbarbitúrico é conhecido por seus efeitos sedativos e hipnóticos, embora seja menos comumente usado em ambientes clínicos em comparação com outros barbitúricos. Sua atividade farmacológica é atribuída à sua capacidade de modular a atividade do neurotransmissor ácido gama-aminobutírico (GABA) no receptor GABA-A, levando à depressão do sistema nervoso central. Além disso, tem aplicações em pesquisa bioquímica e como intermediário na síntese orgânica. Precauções de segurança e manuseio são essenciais devido ao seu potencial de toxicidade e dependência.

Fórmula: C₆H₈N₂O₃

InChI: InChI=1/C6H8N2O3/c1-7-4(9)3-5(10)8(2)6(7)11/h3H2,1-2H3

Chave InChI: InChIKey=VVSASNKOFCZVES-UHFFFAOYSA-N

SMILES: CN1C(=O)N(C)C(=O)CC1=O

Sinónimos:

• 1,3-Dimethyl-1,3-diazacyclohexane-2,4,6-trione
• 1,3-Dimethyl-1,3-diazinane-2,4,6-trione
• 1,3-Dimethyl-2,4,6(1H,3H,5H)-pyrimidinetrione
• 1,3-Dimethyl-pyrimidine-2,4,6-trione
• 1,3-dimethylpyrimidine-2,4,6(1H,3H,5H)-trione
• 2,4,6(1H,3H,5H)-Pyrimidinetrione, 1,3-dimethyl-
• 6-Hydroxy-1,3-dimethyluracil
• Barbituric acid, 1,3-dimethyl-
• Dimethylbarbituric acid
• N,N'-Dimethylbarbituric acid
• N,N′-Dimethyl-2,4,6-pyrimidinetrione
• Nsc 61918
• 1,3-Dimethylbarbituric acid
• 1,3-Dimethylpyrimidine-2,4,6(1H,2H,5H)-trione
• 1,3-Dimethylhexahydropyrimidine-2,4,6-trione
• AKOS B029702
• 1,3-Dimethylbarbituric acid, 99% (dry wt.) water < 6%
• Hexahydro-1,3-dimethylpyrimidine-2,4,6-trione
• 1,3-dimethyl-4,6(1h,3h,5h)-pyrimidinetrione
• 1,3-Dimethyl-2,4,6-Trihydroxy-Pyrimidine
• 6(1h,3h,5h)-pyrimidinetrione,1,3-dimethyl-4

1,3-Dimethylbarbituric acid, 99% (dry wt.), water &lt;6%

CAS: 769-42-6

1,3-Dimethylbarbituric acid is used as a catalyst in the Knoevenagel condensation of a series of aromatic aldehydes. It is also used in the synthesis of 5-aryl-6-(alkyl- or aryl-amino)-1,3-dimethylfuro [2,3-d]pyrimidine derivatives and enantioselective synthesis of isochromene pyrimidinedione deriva

Fórmula: C₆H₈N₂O₃

Pureza: 99%

Cor e Forma: White to cream or pale yellow, Crystals or powder or crystalline powder

Peso molecular: 156.14

Ref: 02-A13692

1,3-Dimethylbarbituric acid

CAS: 769-42-6

Fórmula: C₆H₈N₂O₃

Pureza: 97%

Cor e Forma: Solid

Peso molecular: 156.1393

Ref: IN-DA003DKC

1,3-Dimethylbarbituric acid

CAS: 769-42-6

Fórmula: C₆H₈N₂O₃

Pureza: ≥ 99.0%

Cor e Forma: White to off-white crystalline powder

Peso molecular: 156.14

Ref: 7W-GX0205

1,3-Dimethylbarbituric acid

CAS: 769-42-6

1,3-Dimethylbarbituric acid

Pureza: 99%

Peso molecular: 156.14g/mol

Ref: 54-OR1002579

Urapidil Impurity 4 (1,3-Dimethylbarbituric Acid)

CAS: 769-42-6

Fórmula: C₆H₈N₂O₃

Cor e Forma: White To Off-White Solid

Peso molecular: 156.14

Ref: 4Z-U-0710

1,3-Dimethylbarbituric Acid

CAS: 769-42-6

Fórmula: C₆H₈N₂O₃

Pureza: >98.0%(GC)(T)

Cor e Forma: White to Light yellow to Light orange powder to crystal

Peso molecular: 156.14

Ref: 3B-D1618

1,3-Dimethylbarbituric Acid

CAS: 769-42-6

Cor e Forma: Neat

Ref: 86-MM3980.05

1,3-Dimethyl Barbituric Acid

Produto Controlado

CAS: 769-42-6

Applications 1,3-Dimethyl Barbituric Acid (Urapidil Impurity 4) is a derivative of Barbituric acid (B118650). All of the barbituric acid derivatives which have been reported to have pronounced hypnotic activity are disubstituted in the 5-position.
References Gupta, K., et al.: Eur. J. Med. Chem., 17, 448 (1982), Weber, L., et al.: Curr. Med. Chem., 9, 2085 (2002), Skiles, J., et al.: Curr. Med. Chem., 11, 2911 (2004),

Fórmula: C₆H₈N₂O₃

Cor e Forma: Neat

Peso molecular: 156.14

Ref: TR-D463650

1,3-Dimethyl-2,4,6(1H,3H,5H)-pyrimidinetrione

Produto Controlado

CAS: 769-42-6

1,3-Dimethyl-2,4,6(1H,3H,5H)-pyrimidinetrione is a heterocyclic organic compound, which is synthesized via established chemical procedures involving catalytic methods or direct condensation reactions. This compound is well-known for its role in the biochemical field as a urease inhibitor. Urease, an enzyme that catalyzes the hydrolysis of urea, is targeted by this compound to potentially mitigate issues related to excessive ammonia production in agricultural and medical settings.In addition to its enzymatic inhibition properties, 1,3-Dimethyl-2,4,6(1H,3H,5H)-pyrimidinetrione serves as a pivotal intermediate in barbiturate synthesis. Barbiturates are psychoactive compounds used historically in medicine for their sedative and anesthetic properties. The compound's structure allows it to participate in the Knoevenagel condensation, facilitating the formation of complex molecules essential in pharmaceutical development. These multifunctional applications make it a valuable tool in various scientific research contexts, exploring both inhibitory mechanisms and synthetic pathways for drug discovery and development.

Fórmula: C₆H₈N₂O₃

Pureza: Min. 98 Area-%

Cor e Forma: Powder

Peso molecular: 156.14 g/mol

Ref: 3D-FD128015

1,3-Dimethylbarbituric acid

CAS: 769-42-6

Fórmula: C₆H₈N₂O₃

Pureza: 98.0%

Peso molecular: 156.141

Ref: 10-F078986

Urapidil Impurity 4

CAS: 769-42-6

Fórmula: C₆H₈N₂O₃

Peso molecular: 156.14

Ref: ST-EA-CP-U2004