CAS 78111-17-8

ácido 1,7-dioxaspiro[5.5]undec-10-eno-2-propanoico, α,5-diidroxi-α,10-dimetil-8-[(1R,2E)-1-metil-3-[(2R,4'aR,5R,6'S,8'R,8'aS)-octahidro-8'-hidroxi-6'-[(1S,3S)-1-hidroxi-3-[(2S,3R,6S)-3-metil-1,7-dioxaspiro[5.5]undec-2-il]butil]-7'-metilenespiro[furan-2(3H),2'(3'H)-pirano[3,2-b]pirano]-5-il]-2-propenil]-, (αR,2S,5R,6R,8S)-

Descrição:

ácido 1,7-dioxaspiro[5.5]undec-10-eno-2-propanoico, α,5-diidroxi-α,10-dimetil-8-[(1R,2E)-1-metil-3-[(2R,4'aR,5R,6'S,8'R,8'aS)-octahidro-8'-hidroxi-6'-[(1S,3S)-1-hidroxi-3-[(2S,3R,6S)-3-metil-1,7-dioxaspiro[5.5]undec-2-il]butil]-7'-metilenespiro[furan-2(3H),2'(3'H)-pirano[3,2-b]pirano]-5-il]-2-propenil]-, (αR,2S,5R,6R,8S)- é um composto orgânico complexo caracterizado por sua intrincada estrutura molecular, que inclui múltiplos grupos funcionais, como dioxaspiro, hidroxila e moieties de ácido propanoico. Este composto exibe quiralidade, indicada por seus descritores estereoquímicos, sugerindo que pode existir em múltiplas formas enantioméricas. Sua complexidade estrutural pode conferir propriedades químicas únicas, potencialmente influenciando sua reatividade e interações com sistemas biológicos. A presença de múltiplos anéis e centros estereogênicos sugere que pode ter aplicações em farmacêuticos ou como um intermediário sintético em química orgânica. Além disso, o número CAS do composto, 78111-17-8, permite fácil identificação e referência em bancos de dados químicos. No geral, essa substância representa um exemplo fascinante da síntese orgânica moderna e da diversidade estrutural em compostos químicos.

Fórmula: C₄₄H₆₈O₁₃

InChI: InChI=1/C44H68O13/c1-25-21-34(55-44(23-25)35(46)12-11-31(54-44)24-41(6,50)40(48)49)26(2)9-10-30-14-18-43(53-30)19-15-33-39(57-43)36(47)29(5)38(52-33)32(45)22-28(4)37-27(3)13-17-42(56-37)16-7-8-20-51-42/h9-10,23,26-28,30-39,45-47,50H,5,7-8,11-22,24H2,1-4,6H3,(H,48,49)/b10-9+/t26-,27-,28+,30+,31+,32+,33-,34+,35-,36-,37?,38+,39?,41-,42+,43-,44-/m1/s1

Chave InChI: InChIKey=QNDVLZJODHBUFM-WFXQOWMNSA-N

SMILES: O[C@H]1[C@@]2(O[C@]([C@@H](/C=C/[C@@H]3O[C@]4(CC3)O[C@@]5([C@@](CC4)(O[C@]([C@H](C[C@H](C)[C@]6(O[C@]7(CC[C@H]6C)CCCCO7)[H])O)(C(=C)[C@H]5O)[H])[H])[H])C)(CC(C)=C2)[H])O[C@H](C[C@@](C(O)=O)(C)O)CC1

Sinónimos:

• (αR,2S,5R,6R,8S)-α,5-Dihydroxy-α,10-dimethyl-8-[(1R,2E)-1-methyl-3-[(2R,4′aR,5R,6′S,8′R,8′aS)-octahydro-8′-hydroxy-6′-[(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undec-2-yl]butyl]-7′-methylenespiro[furan-2(3H),2′(3′H)-pyrano[3,2-b]pyran]-5-yl]-2-propen-1-yl]-1,7-dioxaspiro[5.5]undec-10-ene-2-propanoic acid
• 1,7-Dioxaspiro[5.5]undec-10-ene-2-propanoic acid, α,5-dihydroxy-α,10-dimethyl-8-[(1R,2E)-1-methyl-3-[(2R,4′aR,5R,6′S,8′R,8′aS)-octahydro-8′-hydroxy-6′-[(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undec-2-yl]butyl]-7′-methylenespiro[furan-2(3H),2′(3′H)-pyrano[3,2-b]pyran]-5-yl]-2-propen-1-yl]-, (αR,2S,5R,6R,8S)-
• 1,7-Dioxaspiro[5.5]undec-10-ene-2-propanoic acid, α,5-dihydroxy-α,10-dimethyl-8-[(1R,2E)-1-methyl-3-[(2R,4′aR,5R,6′S,8′R,8′aS)-octahydro-8′-hydroxy-6′-[(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undec-2-yl]butyl]-7′-methylenespiro[furan-2(3H),2′(3′H)-pyrano[3,2-b]pyran]-5-yl]-2-propenyl]-, (αR,2S,5R,6R,8S)-
• 1,7-Dioxaspiro[5.5]undec-10-ene-2-propanoic acid, α,5-dihydroxy-α,10-dimethyl-8-[1-methyl-3-[octahydro-8'-hydroxy-6'-[1-hydroxy-3-(3-methyl-1,7-dioxaspiro[5.5]undec-2-yl)butyl]-7'-methylenespiro[furan-2(3H),2'(3'H)-pyrano[3,2-b]pyran]-5-yl]-2-propenyl]-, [2'R-[2'α[R*[1R*[2S*(R*),5R*,6R*,8S*],2E]],4'aβ,6'β[1S*,3S*(2S*,3R*,6S*)],8'α,8'aα]]-
• 1,7-Dioxaspiro[5.5]undec-10-ene-2-propanoic acid, α,5-dihydroxy-α,10-dimethyl-8-[1-methyl-3-[octahydro-8′-hydroxy-6′-[1-hydroxy-3-(3-methyl-1,7-dioxaspiro[5.5]undec-2-yl)butyl]-7′-methylenespiro[furan-2(3H),2′(3′H)-pyrano[3,2-b]pyran]-5-yl]-2-propenyl]-, [2′R-[2′α[R*[1R*[2S*(R*),5R*,6R*,8S*],2E]],4′aβ,6′β[1S*,3S*(2S*,3R*,6S*)],8′α,8′aα]]-
• 1,7-Dioxaspiro[5.5]undecane, acanthifolicin deriv.
• 35-Demethyl-DTX 1
• 35-Demethyldinophysistoxin 1
• Acanthifolicin, 9,10-deepithio-9,10-didehydro-
• Nsc 677083
• Okadaic acid
• Spiro[furan-2(3H),2′(3′H)-pyrano[3,2-b]pyran], acanthifolicin deriv.
• (2R)-2-hydroxy-3-[(2S,5R,6R,8S)-5-hydroxy-8-{(2R,3E)-4-[(2R,4a'R,5R,6'S,8'R,8a'S)-8'-hydroxy-6'-{(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undec-2-yl]butyl}-7'-methylideneoctahydro-3H,3'H-spiro[furan-2,2'-pyrano[3,2-b]pyran]-5-yl]but-3-en-2-yl}-10-methyl-1,7-dioxaspiro[5.5]undec-10-en-2-yl]-2-methylpropanoic acid
• 78111-17-8
• 1,7-Dioxaspiro[5.5]undec-10-ene-2-propanoic acid, alpha,5-dihydroxy-alpha,10-dimethyl-8-[(1R,2E)-1-methyl-3-[(2R,4a'R,5R,6'S,8'R,8a'S)-octahydro-8'-hydroxy-6'-[(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undec-2-yl]butyl]-7'-methylenespiro[furan-2(3H),2'(3'H)-pyrano[3,2-b]pyran]-5-yl]-2-propen-1-yl]-, (alphaR,2S,5R,6R,8S)-
• OKADAIC ACID, 25 UG*
• 9,10-DEEPITHIO-9,10-DIDEHYDROACANTHIOFOLICIN
• Okadaic acid, free acid >98%
• Okadic acid
• OA
• OKADAIC ACID >95% PROTEIN PHOSPHATASE I
• 1,7-Dioxaspiro5.5undec-10-ene-2-propanoic acid, .alpha.,5-dihydroxy-.alpha.,10-dimethyl-8-(1R,2E)-1-methyl-3-(2R,4aR,5R,6S,8R,8aS)-octahydro-8-hydroxy-6-(1S,3S)-1-hydroxy-3-(2S,3R,6S)-3-methyl-1,7-dioxaspiro5.5undec-2-ylbutyl-7-methylenespirofuran-2(3H),2
• 9,10-DEEPITHIO-9,10-DIDEHYDROACANTHIFOLICIN
• OKADAIC ACID FREE ACID
• Okadaic acid,97%
• OKADAICACID,HIGHPURITY
• 9,10-deepithio-9,10-didehydro-acanthifolici
• OKADAIC ACID AMMONIUM SALT WATER-SOLUBLE ANALOG
• OKADAIC ACID, 98+%
• OKADAIC ACID, PROROCENTRUM CONCAVUM
• Ocadaic Acid
• HALOCHONDRINE A
• Okadaic acid from Prorocentrum concavum,OA
• Okadaic acid 35-Demethyl-DTX 1 NSC 677083 35-Demethyldinophysistoxin 1
• OKADAIC ACID SODIUM SALT 98+%
• Blue mussel, homogenized (Okadaic acid)
• 1,7-Dioxaspiro[5.5]undec-10-ene-2-propanoicacid, a,5-dihydroxy-a,10-dimethyl-8-[(1R,2E)-1-methyl-3-[(2R,4'aR,5R,6'S,8'R,8'aS)-octahydro-8'-hydroxy-6'-[(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undec-2-yl]butyl]-7'-methylenespiro[furan-2(
• OKADAIC ACID FROM PROROCENTRUM SP.
• 9,45-Seco-10-demercapto-9,10-didehydroacanthifolicin
• Okadaicacid,Prorocentrumconcavum,highpurity

Okadaic acid, 98%

CAS: 78111-17-8

Okadaic acid, is used as an activator of PKC and inhibitor of PP1 and PP2A phosphatases. The hydrophobic backbone of okadaic acid enables it to enter cells where it stimulates intracellular protein phosphorylation. It mimics the effects of insulin, enhances transmitter release at neuromuscular junct

Fórmula: C₄₄H₆₈O₁₃

Pureza: 98%

Cor e Forma: White, Solid

Peso molecular: 805.02

Ref: 02-J60155

Okadaic acid

CAS: 78111-17-8

Fórmula: C₄₄H₆₈O₁₃

Cor e Forma: Solid

Peso molecular: 805.0029

Ref: IN-DA003AXF

Okadaic acid, Prorocentrum concavum, high purity

CAS: 78111-17-8

Fórmula: C₄₄H₆₈O₁₃

Pureza: >98%

Peso molecular: 805.015

Ref: 10-M02211

Okadaic acid

CAS: 78111-17-8

Fórmula: C₄₄H₆₈O₁₃

Pureza: ≥ 97.0%

Cor e Forma: White crystalline powder or solid

Peso molecular: 805.02

Ref: 7W-GL7691

Okadaic acid, free acid

CAS: 78111-17-8

Okadaic acid, free acid

Fórmula: C₄₄H₆₈O₁₃

Pureza: >98%

Cor e Forma: white lyophilized solid

Peso molecular: 805.00g/mol

Ref: 54-BIM1576

Okadaic Acid

CAS: 78111-17-8

Applications Okadaic acid is a widely distributed marine toxin produced by several phytoplanktonic species and responsible for diarrheic shellfish poisoning in humans. At the molecular level, Okadaic acid is a potent and specific inhibitor of various types of serine/threonine protein phosphatases. Due to this enzymatic inhibition, Okadaic acid was reported to induce numerous alterations in relevant cellular physiological processes, including metabolic pathways such as glucose uptake, lipolysis and glycolysis, heme metabolism and glycogen and protein synthesis. OA. EU regulated marine toxin.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Valdiglesia, V., et al.: J. Toxicol. Enviro. Health., 75, 844 (2012); Kamat, P.K., et al.: Life. Sci., 90, 713 (2012); Valdiglesias, V., et al.: BMC. Genomics., 13, 46 (2012);

Fórmula: C₄₄H₆₈O₁₃

Cor e Forma: Neat

Peso molecular: 805.00

Ref: TR-O515500

Okadaic acid

CAS: 78111-17-8

Inhibitor of PP1 and PP2A protein phosphatases

Fórmula: C₄₄H₆₈O₁₃

Pureza: Min. 95%

Peso molecular: 805 g/mol

Ref: 3D-FO73140

Okadaic acid

CAS: 78111-17-8

Okadaic acid, a polyether marine toxin, is a highly potent and selective protein phosphatase (PP) inhibitor.

Fórmula: C₄₄H₆₈O₁₃

Pureza: 98%

Cor e Forma: White Crystals Or Powder

Peso molecular: 805

Ref: TM-T16381