CAS 78214-33-2

Ginsenosídeo Rh2

Descrição:

Ginsenosídeo Rh2 é um composto natural classificado como uma saponina triterpenoide, derivado principalmente das raízes de Panax ginseng, uma planta conhecida por suas propriedades medicinais. É caracterizado por sua complexa estrutura molecular, que inclui uma espinha dorsal semelhante a um esteroide com moieties de açúcar anexadas, contribuindo para sua atividade biológica. Ginsenosídeo Rh2 é reconhecido por seus potenciais efeitos farmacológicos, incluindo propriedades anticancerígenas, anti-inflamatórias e neuroprotetoras. Tem sido estudado por sua capacidade de modular várias vias de sinalização, influenciando a proliferação celular e a apoptose em células cancerosas. Além disso, Ginsenosídeo Rh2 exibe atividade antioxidante, o que pode ajudar a reduzir o estresse oxidativo. O composto é tipicamente encontrado em baixas concentrações em extratos de ginseng, necessitando de técnicas avançadas de extração e purificação para aplicações de pesquisa e terapêuticas. Seu perfil de segurança e eficácia são assuntos de pesquisa em andamento, destacando a necessidade de mais estudos para entender completamente seus mecanismos e potenciais benefícios à saúde.

Fórmula: C₃₆H₆₂O₈

InChI: InChI=1S/C36H62O8/c1-20(2)10-9-14-36(8,42)21-11-16-35(7)27(21)22(38)18-25-33(5)15-13-26(32(3,4)24(33)12-17-34(25,35)6)44-31-30(41)29(40)28(39)23(19-37)43-31/h10,21-31,37-42H,9,11-19H2,1-8H3/t21-,22+,23+,24-,25+,26-,27-,28+,29-,30+,31-,33-,34+,35+,36-/m0/s1

Chave InChI: InChIKey=CKUVNOCSBYYHIS-IRFFNABBSA-N

SMILES: C[C@]12[C@@]3(C)[C@@]([C@@]([C@@](CCC=C(C)C)(C)O)(CC3)[H])([C@H](O)C[C@@]1([C@]4(C)[C@@](CC2)(C(C)(C)[C@@H](O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)CC4)[H])[H])[H]

Sinónimos:

• (3beta,12beta)-12,20-Dihydroxydammar-24-en-3-yl beta-D-glucopyranoside
• (3β,12β)-12,20-Dihydroxydammar-24-en-3-yl β-<span class="text-smallcaps">D</span>-glucopyranoside
• 20(S)-Ginsenoside Rh₂
• 20(S)-Rh2
• 3-O-β-<span class="text-smallcaps">D</span>-Glucopyranosyl-20(S)-protopanaxadiol
• Dammarane, β-<span class="text-smallcaps">D</span>-glucopyranoside deriv.
• Ginsenoside 20-Rh2
• Ginsenoside Rh₂
• Ginsenoside rh2(S)
• β-<span class="text-smallcaps">D</span>-Glucopyranoside, (3β,12β)-12,20-dihydroxydammar-24-en-3-yl
• Dammarane, β-D-glucopyranoside deriv.
• Ginsenoside Rh2
• β-D-Glucopyranoside, (3β,12β)-12,20-dihydroxydammar-24-en-3-yl
• 3-O-β-D-Glucopyranosyl-20(S)-protopanaxadiol
• (3β,12β)-12,20-Dihydroxydammar-24-en-3-yl β-D-glucopyranoside
• β-D-Glucopyranoside, (3β,12β)-12,20-
• 12β,20-Dihydroxy-5α-dammar-24-en-3β-yl β-D-glucopyranoside
• R-form-Ginsenoside Rh2
• dihydroxydammar-24-en-3-yl

Ginsenoside Rh2

CAS: 78214-33-2

Ginsenoside Rh2 analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Fórmula: C₃₆H₆₂O₈

Pureza: (HPLC) ≥98%

Cor e Forma: Powder

Peso molecular: 622.89

Ref: 11-0154S

Ginsenoside Rh2

CAS: 78214-33-2

Ginsenoside Rh2

Pureza: ≥98%

Peso molecular: 622.87g/mol

Ref: 54-BUP06318

Ginsenoside Rh2

CAS: 78214-33-2

Ginsenoside Rh2 is one of the most active components of red ginseng, controlling cancer and other metabolic diseases including osteoclast differentiation; ginsenoside Rh2 can suppress RANKL-induced osteoclast differentiation in vitro and in vivo through the regulation of c-Fos and NFATc1 expressions, not excluding the involvement of NF-κB and ERK, it is also suggested to be developed as a therapeutic drug for prevention and treatment of osteoporosis.

Fórmula: C₃₆H₆₂O₈

Pureza: 95%~99%

Cor e Forma: White powder

Peso molecular: 622.884

Ref: BP-BP0668

20(s)-Ginsenoside Rh2

CAS: 78214-33-2

Fórmula: C₃₆H₆₂O₈

Pureza: ≥ 98.0%

Cor e Forma: White to off-white powder

Peso molecular: 622.87

Ref: 7W-GC1836

Ginsenoside Rh2

CAS: 78214-33-2

Fórmula: C₃₆H₆₂O₈

Peso molecular: 622.88

Ref: 4Z-G-157005

Ginsenoside Rh2-d6

CAS: 78214-33-2

Fórmula: C₃₆H₅₆D₆O₈

Peso molecular: 628.92

Ref: 4Z-G-157007

Ginsenoside Rh2

CAS: 78214-33-2

Ginsenoside Rh2 (20(S)-Ginsenoside Rh2), an extract of red Panax ginseng, is a potent anti-inflammatory and anticancer drug.

Fórmula: C₃₆H₆₂O₈

Pureza: 99.20% - 99.76%

Cor e Forma: White Powder

Peso molecular: 622.87

Ref: TM-T2959

Ginsenoside rh2

CAS: 78214-33-2

Natural glycoside

Fórmula: C₃₆H₆₂O₈

Pureza: ≥ 90.0 % (HPLC)

Cor e Forma: Powder

Peso molecular: 622.89

Ref: 5G-89683

20(S)-Ginsenoside Rh2

Produto Controlado

CAS: 78214-33-2

Applications 20(S)-Ginsenoside Rh2 is a bioactive metabolite of the ginsenoside component of Panax ginseng that has been shown to exhibit antibacterial effects in vitro.
References Zhang, J. et al.: Eur. J. Pharm., 740, 277 (2014);

Fórmula: C₃₆H₆₂O₈

Cor e Forma: Neat

Peso molecular: 622.87

Ref: TR-G387585

20(s)-Ginsenoside Rh2

CAS: 78214-33-2

20(s)-Ginsenoside Rh2 is a bioactive compound classified as a saponin, which is derived from the root of the Panax ginseng plant. This compound exhibits a wide range of pharmacological activities attributed to its ability to modulate cellular pathways. It exerts its mode of action primarily through the regulation of apoptosis, modulation of immune responses, and inhibition of tumor growth. Mechanistically, it interacts with cellular receptors and signaling molecules, influencing pathways such as NF-κB and MAPK, which are crucial in cell proliferation and apoptosis.

Fórmula: C₃₆H₆₂O₈

Pureza: Min. 98 Area-%

Cor e Forma: Powder

Peso molecular: 622.89 g/mol

Ref: 3D-OG09293

20(S)-Ginsenoside Rh2-d6

Produto Controlado

CAS: 78214-33-2

Fórmula: C₃₆D₆H₅₆O₈

Cor e Forma: Neat

Peso molecular: 628.91

Ref: TR-G410290

Ginsenoside Rh2

CAS: 78214-33-2

Ginsenoside Rh2 is a bioactive compound, which is a triterpenoid saponin derived from the root of the Panax ginseng plant. It operates through multiple biochemical pathways, including the modulation of cell signaling cascades such as the inhibition of cell proliferation and the induction of apoptosis in cancer cells. These actions are primarily mediated through mitochondrial pathways and involve the regulation of pro-apoptotic and anti-apoptotic proteins.

Fórmula: C₃₆H₆₂O₈

Pureza: Min. 95%

Cor e Forma: White Powder

Peso molecular: 622.87 g/mol

Ref: 3D-FG65764

(3β,12β)-12,20-Dihydroxydammar-24-en-3-yl β-D-glucopyranoside

CAS: 78214-33-2

Fórmula: C₃₆H₆₂O₈

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 622.8727

Ref: IN-DA00393A