CAS 78439-06-2

Ceftazidima pentahidratada

Descrição:

Ceftazidima pentahidratada é um antibiótico cefalosporínico de amplo espectro usado principalmente no tratamento de infecções causadas por bactérias Gram-negativas. É caracterizado pela sua capacidade de inibir a síntese da parede celular bacteriana, tornando-o eficaz contra uma variedade de patógenos, incluindo Pseudomonas aeruginosa. A forma pentahidratada indica que o composto contém cinco moléculas de água, o que pode influenciar sua solubilidade e estabilidade. O ceftazidime é tipicamente administrado por injeção e é frequentemente usado em ambientes hospitalares para infecções graves, incluindo aquelas em pacientes imunocomprometidos. Sua estrutura química apresenta um anel beta-lactâmico, que é essencial para sua atividade antibacteriana. O composto é geralmente bem tolerado, mas como todos os antibióticos, pode causar efeitos colaterais, incluindo reações alérgicas e distúrbios gastrointestinais. Devido ao surgimento da resistência a antibióticos, seu uso é frequentemente guiado por testes de suscetibilidade para garantir eficácia contra cepas bacterianas específicas.

Fórmula: C₂₂H₂₂N₆O₇S₂·5H₂O

InChI: InChI=1S/C22H22N6O7S2.5H2O/c1-22(2,20(33)34)35-26-13(12-10-37-21(23)24-12)16(29)25-14-17(30)28-15(19(31)32)11(9-36-18(14)28)8-27-6-4-3-5-7-27;;;;;/h3-7,10,14,18H,8-9H2,1-2H3,(H4-,23,24,25,29,31,32,33,34);5*1H2/b26-13-;;;;;/t14-,18-;;;;;/m1...../s1

Chave InChI: InChIKey=NMVPEQXCMGEDNH-TZVUEUGBSA-N

SMILES: C([O-])(=O)C=1N2[C@@]([C@H](NC(/C(=N\OC(C(O)=O)(C)C)/C3=CSC(N)=N3)=O)C2=O)(SCC1C[N+]=4C=CC=CC4)[H].O

Sinónimos:

• (6R,7R)-7-({(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-[(1-carboxy-1-methylethoxy)imino]acetyl}amino)-8-oxo-3-(pyridinium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
• (6R,7R)-7-({(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-[(1-carboxy-1-methylethoxy)imino]acetyl}amino)-8-oxo-3-(pyridinium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate pentahydrate
• Cefidime
• Ceftadizim
• Glazidim
• Pyridinium, 1-[[(6R,7R)-7-[[(2Z)-(2-amino-4-thiazolyl)[(1-carboxy-1-methylethoxy)imino]acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-, inner salt, hydrate (1:5)
• Pyridinium, 1-[[(6R,7R)-7-[[(2Z)-(2-amino-4-thiazolyl)[(1-carboxy-1-methylethoxy)imino]acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-, inner salt, pentahydrate
• Pyridinium, 1-[[7-[[(2-amino-4-thiazolyl)[(1-carboxy-1-methylethoxy)imino]acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-, inner salt, pentahydrate, [6R-[6α,7β(Z)]]-
• Starcef 1
• pentahydrate (6R,7R)-7-[[(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-(1-hydroxy-2-methyl-1-oxopropan-2-yl)oxyiminoacetyl]amino]-8-oxo-3-(pyridin-1-ium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
• Ceftazidime pentahydrate

Ceftazidime pentahydrate, 95%

CAS: 78439-06-2

Ceftazidime pentahydrate is an antibacterial agent. It is used especially for Pseudomonas and other gram-negative infections in debilitated patients. It is used in the treatment of patients with infections caused by susceptible strains of organisms in the following diseases: lower respiratory tract

Fórmula: C₂₂H₃₂N₆O₁₂S₂

Pureza: 95%

Cor e Forma: Powder or crystals or crystalline powder, White to off-white

Peso molecular: 636.65

Ref: 02-J66460

CEFTAZIDIME CRS

CAS: 78439-06-2

CEFTAZIDIME CRS

Ref: 41-C0690500

Ceftazidime Pentahydrate

CAS: 78439-06-2

Antibiotics nesoi

Fórmula: C₂₂H₂₂N₆O₇S₂·5H₂O

Cor e Forma: White Cream Crystalline Powder

Peso molecular: 636.15196

Ref: 45-1098130

Ceftazidime pentahydrate

CAS: 78439-06-2

Fórmula: C₂₂H₃₂N₆O₁₂S₂

Pureza: %

Cor e Forma: Solid

Peso molecular: 636.6525

Ref: IN-DA005B3Q

Ceftazidime hydrate, contains approx. 10% sodium carbonate

CAS: 78439-06-2

Fórmula: C₂₂H₂₂N₆O₇S₂·xH₂O

Pureza: 95.0 - 102.0 % (on dried basis)

Cor e Forma: White to off-white crystalline powder

Peso molecular: 546.58

Ref: 7W-GA1898

Ceftazidime Pentahydrate

CAS: 78439-06-2

Ceftazidime Pentahydrate

Pureza: ≥98%

Peso molecular: 636.65g/mol

Ref: 54-BUP18349

Ceftazidime hydrate

CAS: 78439-06-2

Fórmula: C₂₂H₂₂N₆O₇S₂·xH₂O

Pureza: 95.0 - 102.0 % (anhydrous basis)

Cor e Forma: White to off-white crystalline powder

Peso molecular: 546.58 (anhydrous)

Ref: 7W-GA6002

Ceftazidime Pentahydrate

CAS: 78439-06-2

Ceftazidime Pentahydrate

Pureza: 95%

Peso molecular: 636.65g/mol

Ref: 54-OR1024612

Ceftazidime hydrate, USP grade

CAS: 78439-06-2

Fórmula: C₂₂H₂₂N₆O₇S₂·xH₂O

Pureza: (HPLC) 95.0 - 102.0 % (dried basis)

Cor e Forma: White to off-white powder or crystals

Peso molecular: 546.58 (anhydrous)

Ref: 7W-GP7286

Ceftazidime RS

CAS: 78439-06-2

Cor e Forma: White To Light Yellow-White Solid Crystalline Powder

Ref: 2K-7000560021

Ceftazidime Pentahydrate

CAS: 78439-06-2

Ceftazidime Pentahydrate is a cephalosporin antibiotic with activity against gram-negative bacilli and may be used to study infectious diseases.

Fórmula: C₂₂H₃₂N₆O₁₂S₂

Pureza: 99.39%

Cor e Forma: White To Cream-Colored Crystalline Powder

Peso molecular: 636.65

Ref: TM-T8261

Ceftazidime Pentahydrate(Contain 1 equivalent of Na2CO3 as stabilizer)

CAS: 78439-06-2

Applications Third generation cephalosporin antibiotic. Antibacterial.
References Brodie, A., et al.: Antimicrob. Agents Chemother., 17, 876 (1980), Richards, D.M., et al.: Drugs, 29, 105 (1985), Abounassif, M.A., et al.: Anal. Profiles Drug Subs., 19, 95 (1990),

Fórmula: C₂₂H₂₂N₆O₇S₂·5H₂O

Cor e Forma: White

Peso molecular: 636.65

Ref: TR-C244100

Ceftazidime-d5 (>90%)

Produto Controlado

CAS: 78439-06-2

Stability Light, Moisture and temperature sensitive
Applications Third generation cephalosporin antibiotic. Antibacterial.
References Brodie, A., et al.: Antimicrob. Agents Chemother., 17, 876 (1980), Richards, D.M., et al.: Drugs, 29, 105 (1985), Abounassif, M.A., et al.: Anal. Profiles Drug Subs., 19, 95 (1990),

Fórmula: C₂₂H₁₇D₅N₆O₇S₂

Pureza: 90%

Cor e Forma: Neat

Peso molecular: 551.61

Ref: TR-C244102

Ceftazidime impurity B

CAS: 78439-06-2

Ceftazidime impurity B is a ceftazidime impurity that is found in the drug Ceftazidime. Ceftazidime is an antibiotic that belongs to the group of cephalosporin antibiotics and inhibits bacterial growth by inhibiting cell wall synthesis. Ceftazidime impurity B has been shown to be toxic to gram-positive bacteria, such as Enterococcus faecium and Staphylococcus aureus, but not to gram-negative bacteria, such as Escherichia coli. In addition, it has been shown to have no effect on the IL-2 receptor of T cells or the binding of penicillin-binding protein. It has also been shown to be safe for injection into mice and rats in toxicity studies.

Fórmula: C₂₂H₂₂N₆O₇S₂

Pureza: Min. 95%

Peso molecular: 546.58 g/mol

Ref: 3D-IC63717

Ceftazidime pentahydrate

CAS: 78439-06-2

A broad-spectrum antibiotic of cephalosporin class, which inhibits bacterial cell wall synthesis by targeting the penicillin-binding protein, involved in peptidoglycan synthesis. This third-generation cephalosporin is very active against Pseudomonas species and can also be used to treat bacterial meningitis as it penetrates in the cerebrospinal fluid.

Fórmula: C₂₂H₃₂N₆O₁₂S₂

Pureza: Min. 98 Area-%

Cor e Forma: White Powder

Peso molecular: 636.65 g/mol

Ref: 3D-AC19871