CAS 78628-80-5

Cloridrato de terbinafina

Descrição:

Cloridrato de terbinafina é um medicamento antifúngico usado principalmente para tratar infecções por dermatófitos, como pé de atleta, micose e fungo nas unhas. Pertence à classe de antifúngicos chamados alilaminas e atua inibindo a enzima esqualeno epoxidase, que é crucial para a síntese de ergosterol, um componente essencial das membranas celulares fúngicas. Essa interrupção leva à morte celular e elimina efetivamente a infecção. Cloridrato de terbinafina é tipicamente administrado por via oral ou tópica, dependendo do tipo e da gravidade da infecção. A substância é caracterizada por sua forma de pó cristalino branco a off-white, com uma solubilidade relativamente baixa em água, o que pode afetar sua absorção e biodisponibilidade. Possui uma fórmula molecular que reflete sua estrutura complexa, e sua farmacocinética envolve extenso metabolismo hepático. Os efeitos colaterais podem incluir distúrbios gastrointestinais, reações cutâneas e, em casos raros, toxicidade hepática. No geral, Cloridrato de terbinafina é um agente potente e amplamente utilizado no tratamento de infecções fúngicas, com um perfil de segurança bem estabelecido quando usado conforme as orientações.

Fórmula: C₂₁H₂₆ClN

InChI: InChI=1/C21H25N/c1-21(2,3)15-8-5-9-16-22(4)17-19-13-10-12-18-11-6-7-14-20(18)19/h5-7,9-14H,16-17H2,1-4H3/b9-5+

Chave InChI: InChIKey=BWMISRWJRUSYEX-SZKNIZGXSA-N

SMILES: C(N(C/C=C/C#CC(C)(C)C)C)C=1C2=C(C=CC1)C=CC=C2.Cl

Sinónimos:

• (2E)-N,6,6-trimethyl-N-(naphthalen-1-ylmethyl)hept-2-en-4-yn-1-amine
• (E)-N-(6,6-Dimethyl-2-Hepten-4-Ynyl)-N-Methyl-1-Naphthalenemethylaminehydroc
• (E)-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalenemethanamine monohydrochloride
• (E)-N-(6,6-dimethyl-2-heptene-4-alkyne)-N-methyl-l-naphthalene methylamine hydrochloride
• 1-Naphthalenemethanamine, N-(6,6-dimethyl-2-hepten-4-ynyl)-N-methyl-, hydrochloride, (E)-
• 1-Naphthalenemethanamine, N-[(2E)-6,6-dimethyl-2-hepten-4-yn-1-yl]-N-methyl-, hydrochloride (1:1)
• 1-Naphthalenemethanamine, N-[(2E)-6,6-dimethyl-2-hepten-4-ynyl]-N-methyl-, hydrochloride
• Bramazil
• Bramizil
• Lamisil
• Lamisil Once
• Lamosil
• Muzonal
• N-(6,6-Dimethyl-2-Hepten-4-Ynyl)-N-Methyl-1-Naphthalenemethanamin(E)-1-
• N-(6,6-Dimethyl-2-Hepten-4-Ynyl)-N-Methyl-1-Naphthalenemethanamin(E)-1-Naphthalenemethanaminmon
• Naphthalenemethanaminmonohydrochloride
• Terbina
• Terbinafine HCl
• Terbinafine・HCL
• Terbine
• Terbutaline hydrochloride
• Terbinafine hydrochloride
• Terbinafine Hydrochloride
• TERNBINAFINEHCL
• N-[(2E)-6,6-DIMETHYL-2-HEPTEN-4-YNYL]-N-METHYL-1-NAPHTHALENEMETHANAMINE
• TRANS-N-(6,6-DIMETHYL-2-HEPTEN-4-YNYL)-N-METHYL-1-NAPHTHYLMETHYLAMINE HYDROCHLORIDE
• Terbinafine hdyrochloride
• Lamisil, N-[(2E)-6,6-Dimethyl-2-hepten-4-ynyl]-N-methyl-1-naphthalenemethanamine
• Trebinafine hydrochloride
• TerbutalineSulfateBase

Terbinafine

CAS: 78628-80-5, 91161-71-6

Fórmula: C₂₁H₂₅N

Pureza: >98.0%(T)(HPLC)

Cor e Forma: White to Light yellow powder to crystal

Peso molecular: 291.44

Ref: 3B-T3677

Terbinafine Hydrochloride

CAS: 78628-80-5, 91161-71-6

Fórmula: C₂₁H₂₅N·HCl

Pureza: >98.0%(T)(HPLC)

Cor e Forma: White to Almost white powder to crystal

Peso molecular: 327.90

Ref: 3B-D2049

Terbinafine hydrochloride

CAS: 78628-80-5

Terbinafine hydrochloride

Fórmula: C₂₁H₂₅N / C₂₁H₂₆CIN

Pureza: 88.6% / 99.7%

Cor e Forma: White. To. Off-White

Peso molecular: 291.1987 / 431.111

Ref: 47-1159

TERBINAFINE FOR SYSTEM SUITABILITY CRS

CAS: 78628-80-5

TERBINAFINE FOR SYSTEM SUITABILITY CRS

Fórmula: C₂₁H₂₆ClN

Peso molecular: 327.8908

Ref: 41-Y0001143

TERBINAFINE HYDROCHLORIDE CRS

CAS: 78628-80-5

TERBINAFINE HYDROCHLORIDE CRS

Fórmula: C₂₁H₂₆ClN

Cor e Forma: White. Powder.

Peso molecular: 327.8908

Ref: 41-Y0000535

Terbinafine Hydrochloride

CAS: 78628-80-5

Aromatic monoamines and their derivatives, salts thereof, nesoi

Fórmula: C₂₁H₂₅N·HCl

Cor e Forma: White Powder

Peso molecular: 291.1987

Ref: 45-1643496

[(2E)-6,6-dimethylhept-2-en-4-yn-1-yl](methyl)(naphthalen-1-ylmethyl)amine hydrochloride

CAS: 78628-80-5

Fórmula: C₂₁H₂₆ClN

Pureza: 97%

Cor e Forma: Solid

Peso molecular: 327.8908

Ref: IN-DA003UI5

Terbinafine hydrochloride

CAS: 78628-80-5

Terbinafine hydrochloride (KWD 2019) is a synthetic allylamine derivative structurally related to naftifine. Terbinafine is active against dermatophytes.

Fórmula: C₂₁H₂₆ClN

Pureza: 99.16% - 99.95%

Cor e Forma: Crystalline Powder

Peso molecular: 327.89

Ref: TM-T1411

({[(2E)-6,6-Dimethylhept-2-en-4-yn-1-yl](methyl)amino}methyl)naphthalene hydrochloride

CAS: 78628-80-5

({[(2E)-6,6-Dimethylhept-2-en-4-yn-1-yl](methyl)amino}methyl)naphthalene hydrochloride

Pureza: 98%

Peso molecular: 327.89g/mol

Ref: 54-OR13685

Terbinafine hydrochloride

CAS: 78628-80-5

Fórmula: C₂₁H₂₅N·HCl

Pureza: 99.0 - 101.0 % (dried basis)

Cor e Forma: White powder

Peso molecular: 327.89

Ref: 7W-GA7211

Terbinafine hydrochloride

CAS: 78628-80-5

Terbinafine hydrochloride

Pureza: ≥98%

Peso molecular: 327.89g/mol

Ref: 54-BUP16916

Terbinafine-d7 HCl

CAS: 78628-80-5

Fórmula: C₂₁H₁₈D₇N·HCl

Cor e Forma: White To Off-White Solid

Peso molecular: 298.48 36.46

Ref: 4Z-T-542

Terbinafine hydrochloride, EP grade

CAS: 78628-80-5

Fórmula: C₂₁H₂₅N·HCl

Pureza: ≤ 0.1%

Cor e Forma: White or almost white powder

Peso molecular: 327.89

Ref: 7W-GA9882

Terbinafine Hydrochloride

CAS: 78628-80-5

Cor e Forma: Neat

Ref: 86-MM0696.00

Terbinafine hydrochloride

CAS: 78628-80-5

Fórmula: C₂₁H₂₅N·ClH

Cor e Forma: Neat

Peso molecular: 327.89

Ref: 04-C17255000

Terbinafine Hydrochloride

CAS: 78628-80-5

Applications An orally active, antimycotic allylamine related to Naftifine. A specfic inhibitor of squalene epoxidase, a key enzyme in fungal ergosterol biosynthesis. Antifungal.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Petranyi, G., et al.: Science, 224, 1239 (1984), Ryder, N.S., et al.: Antimicrob. Agents Chemother., 27, 252 (1985), Evans, E.G.V., et al.: Br. Med. J., 318, 1031 (1999),

Fórmula: C₂₁H₂₅N·ClH

Cor e Forma: Neat

Peso molecular: 327.89

Ref: TR-T107500

Terbinafine hydrochloride

CAS: 78628-80-5

Activator of the two-pore domain potassium channel TASK3

Fórmula: C₂₁H₂₆ClN

Pureza: Min. 98 Area-%

Cor e Forma: Powder

Peso molecular: 327.89 g/mol

Ref: 3D-FT28039

Terbinafine HCl - Bio-X ™

CAS: 78628-80-5

Terbinafine is an antifungal drug that is used in the treatment of dermatophyte infections of the toenails and fingernails. Terbinafine also treats other skin infections. This drug works by inhibiting ergosterol synthesis which in return inhibits fungal squalene monooxygenase. This results in a disruption of fungal cell wall synthesis.

Fórmula: C₂₁H₂₅N•HCl

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 327.89 g/mol

Ref: 3D-BT164461

Terbinafine hydrochloride

CAS: 78628-80-5

Fórmula: C₂₁H₂₆ClN

Pureza: 95.0%

Cor e Forma: Solid

Peso molecular: 327.9

Ref: 10-F332489

Terbinafine Hydrochloride

CAS: 78628-80-5

Fórmula: C₂₁H₂₅NHCl

Peso molecular: 291.4 : 36.46

Ref: ST-EA-CP-T34010