CAS 78858-44-3

(2R)-3-(hexadeciloxi)-2-metoxipropil 2-(trimetilamônio)etil fosfato

Descrição:

A substância química conhecida como (2R)-3-(hexadeciloxi)-2-metoxipropil 2-(trimetilamônio)etil fosfato, com o número CAS 78858-44-3, é um composto de amônio quaternário que exibe propriedades anfifílicas devido às suas características hidrofílicas e hidrofóbicas duais. Este composto apresenta um grupo hexadecil de cadeia longa, que contribui para sua lipofilicidade, enquanto o grupo trimetilamônio fornece uma carga positiva, aumentando sua solubilidade em solventes polares. A presença do grupo fosfato aumenta ainda mais sua hidrofília, tornando-o adequado para várias aplicações nos campos bioquímico e farmacêutico, particularmente em sistemas de liberação de medicamentos e como surfactante. Sua configuração estrutural permite que interaja com membranas biológicas, potencialmente facilitando o transporte de moléculas através de bicamadas lipídicas. Além disso, este composto pode exibir propriedades antimicrobianas, tornando-o de interesse no desenvolvimento de agentes antimicrobianos. No geral, suas características estruturais únicas permitem uma gama de funcionalidades tanto em pesquisa quanto em aplicações industriais.

Fórmula: C₂₅H₅₄NO₆P

InChI: InChI=1/C25H54NO6P/c1-6-7-8-9-10-11-12-13-14-15-16-17-18-19-21-30-23-25(29-5)24-32-33(27,28)31-22-20-26(2,3)4/h25H,6-24H2,1-5H3/t25-/m1/s1

SMILES: CCCCCCCCCCCCCCCCOC[C@H](COP(=O)([O-])OCC[N+](C)(C)C)OC

Sinónimos:

• ethanaminium, 2-[[[[(2R)-3-(hexadecyloxy)-2-methoxypropyl]oxy]hydroxyphosphinyl]oxy]-N,N,N-trimethyl-, inner salt

1-O-Hexadecyl-2-O-methyl-sn-glycero-3-phosphocholine

CAS: 78858-44-3

1-O-Hexadecyl-2-O-methyl-sn-glycero-3-phosphocholine is a useful scaffold, versatile building block, and useful intermediate that can be used in the synthesis of complex compounds. It is a high quality reagent and research chemical that can be used as a reaction component for speciality chemicals. 1-O-Hexadecyl-2-O-methyl-sn-glycero-3-phosphocholine has CAS number 788584443.

Fórmula: C₂₅H₅₄NO₆P

Pureza: Min. 95 Area-%

Peso molecular: 495.67 g/mol

Ref: 3D-H-1844

1-O-Hexadecyl-2-O-methyl-sn-glycero-3-phosphocholine

CAS: 78858-44-3

1-O-Hexadecyl-2-O-methyl-sn-glycero-3-phosphocholine (HPC) is a phospholipid that is synthesized from the essential fatty acid linoleic acid. It has been shown to have an inhibitory effect on leukemia cells, which may be due to its ability to induce apoptosis by inducing the death of tumor cells and inhibiting protein synthesis. HPC also interacts synergistically with other agents such as phorbol esters, which can lead to increased cell death. This drug has been shown to have immunomodulatory effects in fibrosarcoma cells, where it inhibits tumor growth and induces apoptotic cell death. HPC binds to specific antigens and modulates immune responses through the inhibition of diacylglycerol production.

Fórmula: C₂₅H₅₄NO₆P

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 495.68 g/mol

Ref: 3D-FH177698

2-O-methyl PAF C-16

CAS: 78858-44-3

2-O-methyl PAF C-16 is a synthetic analog of platelet-activating factor (PAF) featuring a methyl group attached via an ether linkage at the sn-2 position. While the specific biological activities of 2-O-methyl PAF C-16 remain undercharacterized, studies with its C-18 counterpart have demonstrated its ability to modulate various biological processes. These processes include reducing plasma membrane fluidity and hindering the invasiveness of tumor cells in embryonic chick hearts. Furthermore, in rat astrocytes, the C-18 analog prompts the release of significant amounts of nitric oxide (NO) through a mechanism that involves the activation of nitric oxide synthase (NOS).

Fórmula: C₂₅H₅₄NO₆P

Cor e Forma: Solid

Peso molecular: 495.7

Ref: TM-T84610