CAS 79517-01-4

Octreotida

Descrição:

Octreotida é um análogo sintético de octapeptídeo da somatostatina, um hormônio que ocorre naturalmente e inibe a secreção de vários outros hormônios e substâncias no corpo. É utilizado principalmente na área médica por sua capacidade de reduzir os níveis de hormônio do crescimento e gerenciar condições como acromegalia, certos tipos de tumores e diarreia severa associada a tumores neuroendócrinos. Octreotida exibe uma alta afinidade pelos receptores de somatostatina, particularmente o subtipo 2, o que contribui para seus efeitos terapêuticos. O composto é tipicamente administrado por vias subcutâneas ou intravenosas e tem uma meia-vida mais longa em comparação com a somatostatina natural, permitindo uma dosagem menos frequente. Em termos de propriedades físicas, Octreotida é um pó branco a off-white que é solúvel em água e exibe estabilidade sob condições de armazenamento apropriadas. Sua estrutura molecular inclui uma ligação de dissulfeto cíclica, que aumenta sua resistência à degradação enzimática, tornando-o eficaz para uso clínico. No geral, Octreotida representa um avanço significativo no manejo de distúrbios relacionados a hormônios.

Fórmula: C₄₉H₆₆N₁₀O₁₀S₂

InChI: InChI=1/C49H66N10O10S2/c1-28(61)39(25-60)56-48(68)41-27-71-70-26-40(57-43(63)34(51)21-30-13-5-3-6-14-30)47(67)54-37(22-31-15-7-4-8-16-31)45(65)55-38(23-32-24-52-35-18-10-9-17-33(32)35)46(66)53-36(19-11-12-20-50)44(64)59-42(29(2)62)49(69)58-41/h3-10,13-18,24,28-29,34,36-42,52,60-62H,11-12,19-23,25-27,50-51H2,1-2H3,(H,53,66)(H,54,67)(H,55,65)(H,56,68)(H,57,63)(H,58,69)(H,59,64)/t28-,29?,34-,36+,37+,38-,39-,40+,41+,42+/m1/s1

Sinónimos:

• Ccris 8708
• D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-((1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl)-L-cysteinamide cyclic (2-7)-disulfide acetate (salt)
• D-Phenylalanyl-L-hemicystyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-hemicystyl-L-threoninol cyclic (2-7)-disulfide acetate (salt)
• L-Cysteinamide, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-(2-hydroxy-1-(hydroxymethyl)propyl)-, cyclic (2-7)-disulfide, (R-(R*,R*))-, acetate (salt)
• (Preservative Free)
• Sms 201-995
• Sandostatin
• Sandostatin LAR
• Sandostatin LAR Depot
• Unii-75R0U2568I
• (4R,7S,10S,13R,16S,19R)-10-(4-aminobutyl)-16-benzyl-N-[(2R,3R)-1,3-dihydroxybutan-2-yl]-7-(1-hydroxyethyl)-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-19-(D-phenylalanylamino)-1,2-dithia-5,8,11,14,17-pentaazacycloicosane-4-carboxamide acetate (1:1)

Octreotide

CAS: 79517-01-4

Octreotide is a longer acting synthetic octapeptide analog of the naturally occurring hormone somatostatin. It inhibits the secretion of gastro-entero-pancreatic peptide hormones and the release of growth hormones. Melacini et al. studied the conformation of the peptide in solution by NMR. CAS Number (net): 83150-76-9.

Fórmula: C₄₉H₆₆N₁₀O₁₀S₂

Pureza: ≥ 99.5%

Cor e Forma: White

Peso molecular: 1019.26

Ref: 01-4042822

OCTREOTIDE CRS

CAS: 79517-01-4

OCTREOTIDE CRS

Ref: 41-Y0002104

OCTREOTIDE FOR NMR IDENTIFICATION CRS

CAS: 79517-01-4

OCTREOTIDE FOR NMR IDENTIFICATION CRS

Ref: 41-Y0002105

Octreotide Acetate

CAS: 79517-01-4

Polypeptide, protein and glycoprotein hormones, their derivatives and structural analogues, nesoi

Fórmula: C₄₉H₆₆N₁₀O₁₀S₂·xC₂H₄O₂

Cor e Forma: White Powder

Peso molecular: 1018.44048

Ref: 45-1477604

Octreotide Acetate

CAS: 79517-01-4

Fórmula: C₅₁H₇₀N₁₀O₁₂S₂

Pureza: 99%

Cor e Forma: Solid

Peso molecular: 1079.2913

Ref: IN-DA019FSF

Octreotide Acetate

CAS: 79517-01-4

Octreotide Acetate

Pureza: ≥98%

Peso molecular: 1079.3g/mol

Ref: 54-BUP10206

Octreotide acetate

CAS: 79517-01-4

Fórmula: C₄₉H₆₆N₁₀O₁₀S₂·x(CH₃COOH)

Pureza: ≥ 98.0%

Cor e Forma: White to off-white powder

Peso molecular: 1019.24 (free acid)

Ref: 7W-GP4360

Octreotide Acetate

CAS: 79517-01-4

Fórmula: C₄₉H₆₆N₁₀O₁₀S₂

Pureza: 95%~99%

Cor e Forma: White to Off-white Powder

Peso molecular: 1019.24

Ref: BP-BPPG052

Octreotide Acetate

CAS: 79517-01-4

Fórmula: C₄₉H₆₆N₁₀O₁₀S₂·2C₂H₄O₂

Peso molecular: 1019.25 2 60.05

Ref: 4Z-PO-036002

Octreotide Acetate

CAS: 79517-01-4

Octreotide Acetate (Sandostatin) is a potent, long-acting synthetic somatostatin octapeptide analog that inhibits secretion of growth hormone.

Fórmula: C₅₁H₇₀N₁₀O₁₂S₂

Pureza: 99.03% - 99.87%

Cor e Forma: Less To Off-White Lyophilised Solid Colourless To Off-White Lyophilised Solid

Peso molecular: 1079.3

Ref: TM-T4119

Octreotide Acetate

CAS: 79517-01-4

Applications Octapeptide analog of Somatostatin. A gastric antisecretory agent. Used in treatment of acromegaly.
References Bauer, W., et al.: Life Sci., 31, 1133 (1982), Plewe, G., et al.: Lancet, 2, 782 (1984), Kraenzlin, M.E., et al.: Experientia, 41, 738 (1985), del Pozo, E., et al.: Acta Endocrinol., 111, 433 (1986),

Fórmula: C₄₉H₆₆N₁₀O₁₀S₂·C₂H₄O₂

Cor e Forma: White To Off-White

Peso molecular: 1079.29

Ref: TR-O239950

Octreotide acetate

CAS: 79517-01-4

Octapeptide analog of Somatostatin; inhibits insulin and growth hormones

Fórmula: C₄₉H₆₆N₁₀O₁₀S₂·xCH₃COOH

Pureza: Min. 98 Area-%

Cor e Forma: White Off-White Powder

Peso molecular: 1,019.24 g/mol

Ref: 3D-FO26520

Octreotide Acetate

CAS: 79517-01-4

Pureza: 99%

Peso molecular: 1079.300049

Ref: 10-F864034