CAS 79907-44-1

Procianidina B2 3,3′-di-O-galato

Descrição:

Procianidina B2 3,3′-di-O-galato é um composto polifenólico pertencente à família dos flavonoides, especificamente um tipo de proantocianidina. É caracterizado por sua estrutura complexa, que inclui múltiplos anéis fenólicos e grupos galoyl, contribuindo para suas propriedades antioxidantes. Este composto é conhecido por sua presença em várias fontes vegetais, particularmente em frutas, sementes e certos tipos de chá. Procianidina B2 3,3′-di-O-galato exibe atividades biológicas significativas, incluindo efeitos anti-inflamatórios, anticancerígenos e cardioprotetores, tornando-o de interesse na pesquisa nutricional e farmacêutica. Sua solubilidade pode variar dependendo do solvente, e geralmente é mais solúvel em solventes orgânicos do que em água. A estabilidade do composto pode ser influenciada por fatores como pH e temperatura, que são considerações importantes tanto na ciência dos alimentos quanto na farmacologia. No geral, Procianidina B2 3,3′-di-O-galato é um composto valioso por seus potenciais benefícios à saúde e seu papel no estudo de antioxidantes naturais.

Fórmula: C₄₄H₃₄O₂₀

InChI: InChI=1/C44H34O20/c45-19-11-26(51)34-32(12-19)61-40(16-2-4-22(47)25(50)6-16)42(64-44(60)18-9-30(55)38(58)31(56)10-18)36(34)35-27(52)14-23(48)20-13-33(62-43(59)17-7-28(53)37(57)29(54)8-17)39(63-41(20)35)15-1-3-21(46)24(49)5-15/h1-12,14,33,36,39-40,42,45-58H,13H2/t33-,36-,39-,40-,42-/m1/s1

Chave InChI: InChIKey=KTLUHRSHFRODPS-RIQPQZJCSA-N

SMILES: O(C(=O)C1=CC(O)=C(O)C(O)=C1)[C@@H]2[C@H](C=3C(O[C@@H]2C4=CC(O)=C(O)C=C4)=CC(O)=CC3O)C5=C6C(C[C@@H](OC(=O)C7=CC(O)=C(O)C(O)=C7)[C@H](O6)C8=CC(O)=C(O)C=C8)=C(O)C=C5O

Sinónimos:

• (-)-Epicatechin-3-O-galloyl-(4β,8)-(-)-epicatechin-3-O-gallate
• (2R,3R)-3-O-Galloylepicatechin-4β,8-[(2R,3R)-3-O-galloylepicatechin]
• 3,3′-Digalloylprocyanidin B2
• Benzoic acid, 3,4,5-trihydroxy-, (2R,2′R,3R,3′R,4R)-2,2′-bis(3,4-dihydroxyphenyl)-3,3′,4,4′-tetrahydro-5,5′,7,7′-tetrahydroxy[4,8′-bi-2H-1-benzopyran]-3,3′-diyl ester
• Benzoic acid, 3,4,5-trihydroxy-, 2,2′-bis(3,4-dihydroxyphenyl)-3,3′,4,4′-tetrahydro-5,5′,7,7′-tetrahydroxy[4,8′-bi-2H-1-benzopyran]-3,3′-diyl ester, [2R-[2α,3α,4β(2′R*,3′R*)]]-
• Proanthocyanidin B2 3,3′-O-gallate
• Procyanidin B₂ 3,3′-di-O-gallate
• [3-O-Galloyl]-(-)-epicatechin-(4β,8)-(+)-epicatechin-3-O-gallate
• benzoic acid, 3,4,5-trihydroxy-, (2R,2'R,3R,3'R,4R)-2,2'-bis(3,4-dihydroxyphenyl)-3,3',4,4'-tetrahydro-5,5',7,7'-tetrahydroxy[4,8'-bi-2H-1-benzopyran]-3,3'-diyl ester
• Procyanidin B2 3,3′-di-O-gallate
• Benzoic acid, 3,4,5-trihydroxy-, 2,2'-bis(3,4-dihydroxyphenyl)-3,3',4,4'-tetrahydro-5,5',7,7'-tetrahydroxy[4,8'-bi-2H-1-benzopyran]-3,3'-diyl ester, [2R-[2.alpha.,3.alpha.,4.beta.(2'R*,3'R*)]]-
• Aids-082250
• (2R,2'R,3R,3'R,4R)-2,2'-bis(3,4-dihydroxyphenyl)-5,5',7,7'-tetrahydroxy-[4,8'-bichroman]-3,3'-diyl bis(3,4,5-trihydroxybenzoate)
• (2R,3R)-3-o-Galloylepicatechin-4.beta.,8-[(2R,3R)-3-o-galloylepicatechin]
• Aids082250
• [(2R,3R,4R)-2-(3,4-dihydroxyphenyl)-4-[(2R,3R)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-(3,4,5-trihydroxybenzoyl)oxy-chroman-8-yl]-5,7-dihydroxy-chroman-3-yl] 3,4,5-trihydroxybenzoate
• Procyanidin B2 3,3'-di-O-gallate (&gt

2-[(2r,3r,4s,5r,6s)-6-[(1s)-1-[(2s,5r,7s,8r,9s)-2-[(5s)-5-[(2r,3s,4r,5r)-5-[(3s,4s,5r,6s)-6-hydroxy-4-methoxy-3,5,6-trimethyl-tetrahydropyran-2-yl]-4-methoxy-3-methyl-tetrahydrofuran-2-yl]-5-methyl-tetrahydrofuran-2-yl]-9-methoxy-2,8-dimethyl-1,6-dioxaspi

CAS: 79907-44-1

Fórmula: C₄₄H₃₄O₂₀

Pureza: 97%

Cor e Forma: Solid

Peso molecular: 882.7288

Ref: IN-DA0054WP

Procyanidin B2 3,3'-di-O-gallate (>80%)

Produto Controlado

CAS: 79907-44-1

Applications Procyanidin B2 3,3'-di-O-gallate is an important compound whose activity results in the inhibition of growth pertaining to human prostate carcinoma cell lines. Coming from the group of compounds known as flavonoids, Procyanidin B2 3,3'-di-O-gallate shows interesting biological activities relating to various human cancer diseases.
References Saito, A. et al.: Heterocycles, 80, 1081 (2010); Shrestha, S.P. et al.: Pharm. Res., 29, 856 (2012);

Fórmula: C₄₄H₃₄O₂₀

Pureza: >80%

Cor e Forma: Neat

Peso molecular: 882.73

Ref: TR-P755825

Procyanidin B2 3,3'-di-o-gallate

CAS: 79907-44-1

Procyanidin B2 3,3'-di-o-gallate (PB2DOG) is a gallotannin that can be found in the leaves of the dogwood tree. It has dose-dependent effects on the serine protease activity of butanol, which is used as a model for pancreatic lipase. PB2DOG also inhibits the activity of viruses such as hepatitis C and herpes simplex virus type 1, and cancer cells such as du145 and japonica. PB2DOG has been shown to induce apoptosis in cancer cells by reducing DNA synthesis and inhibiting protein synthesis. The mechanism behind this effect is not fully understood, but it may be related to its ability to inhibit cCAAT/enhancer binding protein (C/EBP), an important transcription factor for cell proliferation.

Fórmula: C₄₄H₃₄O₂₀

Pureza: Min. 95%

Peso molecular: 882.7 g/mol

Ref: 3D-EDA90744