CAS 80-49-9
:Metobrometo de homatropina
Descrição:
Metobrometo de homatropina é um agente anticolinérgico sintético usado principalmente em oftalmologia para induzir midríase (dilatação da pupila) e cicloplegia (paralisia do músculo ciliar). É um composto de amônio quaternário, o que significa que carrega uma carga positiva, aumentando sua solubilidade em água e limitando sua capacidade de atravessar a barreira hematoencefálica. Essa característica reduz os efeitos colaterais no sistema nervoso central em comparação com outros anticolinérgicos. A substância é tipicamente administrada como colírio e é conhecida por seu início de ação relativamente rápido e duração moderada do efeito. Além de suas aplicações oftálmicas, também pode ser usada em outros contextos médicos onde os efeitos anticolinérgicos são desejados. Efeitos colaterais comuns podem incluir boca seca, visão embaçada e aumento da pressão intraocular. Devido ao seu perfil farmacológico específico, Metobrometo de homatropina é uma ferramenta valiosa tanto em ambientes diagnósticos quanto terapêuticos nos cuidados oculares.
Fórmula:C17H24BrNO3
InChI:InChI=1/C16H21NO3/c1-17-12-7-8-13(17)10-14(9-12)20-16(19)15(18)11-5-3-2-4-6-11/h2-6,12-15,18H,7-10H2,1H3/t12-,13+,14+,15?
Chave InChI:InChIKey=FUFVKLQESJNNAN-RIMUKSHENA-M
SMILES:C[N+]1(C)[C@]2(C[C@H](OC(C(O)C3=CC=CC=C3)=O)C[C@@]1(CC2)[H])[H].[Br-]
Sinónimos:- 1α<span class="text-smallcaps">H</smallcap>,5α<smallcap>H</span>-Tropanium, 3α-hydroxy-8-methyl-, bromide, mandelate
- 1αH,5αH-Tropanium, 3α-hydroxy-8-methyl-, bromide, mandelate
- 8-Azoniabicyclo[3.2.1]octane, 3-[(2-hydroxy-2-phenylacetyl)oxy]-8,8-dimethyl-, bromide (1:1), (3-endo)-
- 8-Azoniabicyclo[3.2.1]octane, 3-[(hydroxyphenylacetyl)oxy]-8,8-dimethyl-, bromide, endo-
- 8-Methylhomatropinium bromide
- Arkitropin
- Camatropine
- Esopin
- Helbatropin
- Homapin
- Homatrocel
- Homatromide
- Homatropil
- Homatropine Methylbromide
- Homatropine methobromide
- Homatropinmethylbromid
- Homolone
- Malcotran
- Mesopin
- Methatropin
- Methatropine
- Methylbromure d'homatropine
- Methylhomatropine bromide
- Methylhomatropine hydrobromide
- Methylhomatropinium bromide
- Metilbromuro De Homatropina
- Novatrin
- Novatrine
- Novatropin
- Novatropine
- Nsc 34399
- Sed-Tems
- Sethyl
- Tropinium methobromide mandelate
- 3-{[hydroxy(phenyl)acetyl]oxy}-8,8-dimethyl-8-azoniabicyclo[3.2.1]octane bromide
- N-methylhomatropinium bromide
- dl-homatropine methyl bromide
- 8-Azoniabicyclo[3.2.1]octane, 3-[(hydroxyphenylacetyl)oxy]-8,8-dimethyl-, bromide, (3-endo)-
- (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl hydroxy(phenyl)acetate - bromomethane (1:1)
- (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl hydroxy(phenyl)acetate
- Homatropine methyl bromide
- dl-methylbromide
- methylhomatropine
- 3-alpha-hydroxy-8-methyl-1-alpha-h,5-alpha-h-tropaniumbromidemandelate
- 3-((hydroxyphenylacetyl)oxy)-8,8-dimethyl-8-azoniabicyclo(3.2.1)octanbro
- endo-mid
- 8-methyl-homatropiniubromide
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13 produtos.
Homatropine Methyl Bromide
CAS:Fórmula:C17H24BrNO3Pureza:>99.0%(T)Cor e Forma:White to Almost white powder to crystalPeso molecular:370.29HOMATROPINE METHYLBROMIDE FOR SYSTEM SUITABILITY CRS
CAS:HOMATROPINE METHYLBROMIDE FOR SYSTEM SUITABILITY CRSFórmula:C16H21NO3Cor e Forma:PowderPeso molecular:275.3428HOMATROPINE METHYLBROMIDE CRS
CAS:HOMATROPINE METHYLBROMIDE CRSFórmula:C16H21NO3Cor e Forma:PowderPeso molecular:275.3428Homatropine Methylbromide
CAS:Vegetable alkaloids, natural or reproduced by synthesis, their salts and other derivatives, nesoiFórmula:C17H24BrNO3Cor e Forma:White Colorless PowderPeso molecular:370.28Methylhomatropine (bromide)
CAS:Fórmula:C17H24BrNO3Pureza:98%Cor e Forma:SolidPeso molecular:370.2814Homatropine Methylbromide
CAS:<p>Homatropine Methylbromide is the methyl bromide salt of homatropine, a synthetic tertiary amine alkaloid with antimuscarinic properties.</p>Fórmula:C17H24BrNO3Pureza:98.97%Cor e Forma:SolidPeso molecular:370.29Homatropine Methylbromide
CAS:Produto ControladoFórmula:C17H24NO3·BrCor e Forma:NeatPeso molecular:370.28Homatropine methylbromide
CAS:Produto ControladoFórmula:C17H24NO3·BrCor e Forma:NeatPeso molecular:370.28Homatropine methyl bromide
CAS:Homatropine methyl bromide is a drug that belongs to the class of anticholinergic drugs. It is used as a pharmaceutical preparation and is used in the treatment of glaucoma, diagnosis of myasthenia gravis, and as an antidote for organophosphate poisoning. Homatropine methyl bromide can be used to control diastolic pressure. This drug binds to acetylcholine receptors and increases the time needed for hydrochloric acid to break down propranolol hydrochloride. The binding constants for this drug are high, which means it has a strong affinity for acetylcholine receptors. Homatropine methyl bromide is chemically stable and does not react with fatty acids or other chemicals.Fórmula:C17H24NO3•BrPureza:Min. 95%Peso molecular:370.28 g/molHomatropine Methylbromide
CAS:Produto Controlado<p>Applications Homatropine methylbromide or Methylhomatropine bromide is a quaternary ammonium salt of methylhomatropine. Methylhomatropine is a peripherally acting anticholinergic medication that inhibits muscarinic acetylcholine receptors and thus the parasympathetic nervous system. Methylhomatropine does not cross the blood–brain barrier. Methylhomatropine is used, in addition to papaverine, as component of mild drugs that help "flush" the bile.<br>References Schroeder, F., et al.: Biochemistry, 34, 11919 (1995); Krungkrai, J., et al.: Bioorg. Med. Chem., 15, 483 (2005); Zeng, B., et al.: Microbiology, 152, 2355 (2006); Hongmanee, P., et al.: Antimicrob. Agents Chemother., 51, 1105 (2007);<br></p>Fórmula:C17H24NO3·BrCor e Forma:White To Off-WhitePeso molecular:370.28
