CAS 816-94-4

1,2-Distearoil-sn-glicero-3-fosfocolina

Descrição:

1,2-Distearoil-sn-glicero-3-fosfocolina (DSPC) é um fosfolípido comumente utilizado em aplicações bioquímicas e farmacêuticas. É caracterizado por suas duas longas cadeias de ácidos graxos saturados, especificamente ácido esteárico, que contribuem para suas propriedades hidrofóbicas, e um grupo cabeça de fosfocolina que confere hidrofobicidade. Essa natureza anfifílica permite que o DSPC forme bicamadas lipídicas, tornando-se um componente crucial na formação de lipossomos e nanopartículas lipídicas para sistemas de entrega de medicamentos. O DSPC possui uma alta temperatura de transição de fase, o que melhora a estabilidade das formulações lipídicas em temperaturas fisiológicas. Também é conhecido por sua capacidade de encapsular compostos hidrofílicos e hidrofóbicos, tornando-o versátil em várias aplicações, incluindo entrega de vacinas e terapia gênica. Além disso, o DSPC é biocompatível e biodegradável, o que é essencial para seu uso em formulações médicas e cosméticas. Sua integridade estrutural e funcionalidade o tornam uma substância valiosa no desenvolvimento de nanotransportadores e outros sistemas à base de lipídios em ambientes de pesquisa e clínicos.

Fórmula: C₄₄H₈₈NO₈P

InChI: InChI=1/C44H88NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-43(46)50-40-42(41-52-54(48,49)51-39-38-45(3,4)5)53-44(47)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h42H,6-41H2,1-5H3/t42-/m1/s1

Chave InChI: InChIKey=NRJAVPSFFCBXDT-HUESYALOSA-N

SMILES: [C@H](OC(CCCCCCCCCCCCCCCCC)=O)(COP(OCC[N+](C)(C)C)(=O)[O-])COC(CCCCCCCCCCCCCCCCC)=O

Sinónimos:

• (2R)-2,3-bis(octadecanoyloxy)propyl 2-(trimethylammonio)ethyl phosphate
• (R)-(7-Lauroyl-4-oxido-10-oxo-3,5,9-trioxa-4-phosphaheptacosyl)trimethylammonium 4-oxide
• (R)-(7-Lauroyl-4-oxido-10-oxo-3,5,9-trioxa-4-phosphaheptacosyl)trimethylammonium-4-oxid
• 1,2-<span class="text-smallcaps">L</span>-α-Distearoylphosphatidylcholine
• 1,2-Bis(stearoyl)-sn-glycero-3-phosphocholine
• 1,2-Dioctadecanoyl-sn-glycero-3-phosphocholine
• 1,2-Distearoyl-3-sn-phosphatidylcholine
• 1,2-Distearoyl-<span class="text-smallcaps">L</span>-α-glycerophosphocholine
• 1,2-Distearoyl-L-α-glycerophosphocholine
• 1,2-Distearoyl-sn-3-phosphacholine
• 1,2-Distearoyl-sn-3-phosphocholine
• 1,2-Distearoyl-sn-glycero-3-phosphatidylcholine
• 1,2-Distearoyl-sn-glycero-3-phosphocholine
• 1,2-Distearoyl-sn-glycero-3-phosphorylcholine
• 1,2-Distearoyl-sn-glycerophosphocholine
• 1,2-L-α-Distearoylphosphatidylcholine
• 3,5,9-Trioxa-4-phosphaheptacosan-1-aminium, 4-hydroxy-N,N,N-trimethyl-10-oxo-7-((1-oxooctadecyl)oxy)-, hydroxide, inner salt, 4-oxide, (R)-
• 3,5,9-Trioxa-4-phosphaheptacosan-1-aminium, 4-hydroxy-N,N,N-trimethyl-10-oxo-7-[(1-oxooctadecyl)oxy]-, inner salt, 4-oxide, (7R)-
• 3,5,9-Trioxa-4-phosphaheptacosan-1-aminium, 4-hydroxy-N,N,N-trimethyl-10-oxo-7-[(1-oxooctadecyl)oxy]-, inner salt, 4-oxide, (R)-
• 4-Hydroxy-N,N,N-trimethyl-10-oxo-7-((1-oxooctadecyl)oxy)-3,5,9-trioxa-4-phosphaheptacosan-1-aminium hydroxide, inner salt, 4-oxide, (R)-
• 4-oxido de (R)-(7-lauroil-4-oxido-10-oxo-3,5,9-trioxa-4-fosfaheptacosil)trimetilamonio
• 4-oxyde de (R)-(7-lauroyl-4-oxydo-10-oxo-3,5,9-trioxa-4-phosphaheptacosyl)trimethylammonium
• <span class="text-smallcaps">L</span>-DSPC
• <span class="text-smallcaps">L</span>-Distearoyllecithin
• <span class="text-smallcaps">L</span>-α-Distearoylphosphatidylcholine
• <span class="text-smallcaps">L</span>-β,γ-Distearoyl-α-lecithin
• <span class="text-smallcaps">L</span>-β,γ-Distearoyl-α-phosphatidylcholine
• Choline phosphate, 3-ester with <span class="text-smallcaps">L</span>-1,2-distearin
• Choline phosphate, 3-ester with L-1,2-distearin
• Choline, hydroxide, dihydrogen phosphate, inner salt, ester with 1,2-distearin, <span class="text-smallcaps">L</span>-
• Choline, hydroxide, dihydrogen phosphate, inner salt, ester with 1,2-distearin, L-
• Coatsome MC 8080
• Dioctadecanoyl-<span class="text-smallcaps">L</span>-α-glycerophosphorylcholine
• Dioctadecanoyl-L-α-glycerophosphorylcholine
• Distearoyl sn-3-phosphatidylcholine
• Distearoyl-<span class="text-smallcaps">L</span>-α-glycerophosphocholine
• Distearoyl-<span class="text-smallcaps">L</span>-α-lecithin
• Distearoyl-<span class="text-smallcaps">L</span>-α-phosphatidylcholine
• Distearoyl-L-α-glycerophosphocholine
• Distearoyl-L-α-lecithin
• Distearoyl-L-α-phosphatidylcholine
• Distearoyl-sn-glycero-3-phosphocholine
• Distearoylphosphatidylcholine
• Dspc
• L-Alpha-Phosphatidylcholine, Distearoyl
• L-Distearoyllecithin
• L-beta,gamma,Disteroyl-alpha-lecithin
• L-α-Distearoylphosphatidylcholine
• L-β,γ-Distearoyl-α-lecithin
• L-β,γ-Distearoyl-α-phosphatidylcholine
• Unii-043Ipi2M0K
• [(2R)-2,3-Di(octadecanoyloxy)propyl] 2-(trimethylazaniumyl)ethyl phosphate
• β,γ-Distearoyl <span class="text-smallcaps">L</span>-α-phosphatidylcholine
• β,γ-Distearoyl L-α-phosphatidylcholine
• [(2R)-2,3-distearoyloxypropyl] 2-(trimethylammonio)ethyl phosphate
• L-A-PHOSPHATIDYLCHOLINE DISTEAROYL*CRYST SYNTHETIC
• L-α-Phosphatidylcholine, distearoyl
• 18:0 PC
• PC(18:0/18:0)
• (R)-2,3-Bis(stearoyloxy)propyl (2-(triMethylaMMonio)ethyl) phosphate
• propyl (2-(trimethylammonio)
• Distearoyl-L-ALPHA-phosphatidyl choline
• L-BETA,GAMMA-DISTEAROYL-ALPHA-LECITHIN
• -2,3-Bis(stearoyloxy)
• 3-sn-phosphatidylcholine, 1,2-distearoyl
• 1,2-Dioleoyl-sn-Glycero-3-Phsophocholine
• 3-sn-Phosphatidylcholine, 1,2-distearoyl, L-α-Phosphatidylcholine, distearoyl, L-β,γ-Distearoyl-α-lecithin
• L-A-PHOSPHATIDYLCHOLINE, DISTEAROYL
• L-á-Phosphatidylcholine distearoyl
• 1,2-Distearoyl-sn-glycero-3-PC
• [O-(1-O,2-O-Distearoyl-L-glycero-3-phospho)choline]anion
• DISTEAROYL LECITHIN
• 1,2-Distearoyl-sn-glycero-3-phosphocholine, 3-sn-Phosphatidylcholine, 1,2-distearoyl, L-α-Phosphatidylcholine, distearoyl, L-β,γ-Distearoyl-α-lecithin
• L-b,g-Distearoyl-a-lecithin, DSPC

1,2-Distearoyl-sn-glycero-3-phosphocholine

CAS: 816-94-4

Fórmula: C₄₄H₈₈NO₈P

Pureza: >95.0%(T)(HPLC)

Cor e Forma: White to Almost white powder to crystal

Peso molecular: 790.16

Ref: 3B-D3926

1,2-Distearoyl-sn-glycero-3-phosphocholine

CAS: 816-94-4

Bachem ID: 4005619.

Fórmula: C₄₄H₈₈NO₈P

Pureza: >99%

Cor e Forma: White

Peso molecular: 790.16

Ref: 01-4005619

1,2-Distearoyl-sn-glycero-3-phosphocholine

CAS: 816-94-4

Lecithins and other phosphoaminolipids, nesoi

Fórmula: C₄₄H₈₈NO₈P

Cor e Forma: White Powder

Peso molecular: 789.62476

Ref: 45-1222829

3,5,9-Trioxa-4-phosphaheptacosan-1-aminium,4-hydroxy-N,N,N-trimethyl-10-oxo-7-[(1-oxooctadecyl)oxy]-, inner salt,4-oxide, (7R)-

CAS: 816-94-4

Fórmula: C₄₄H₈₈NO₈P

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 790.1452

Ref: IN-DA00ID72

1,2-Distearoyl-sn-glycero-3-phosphorylcholine

CAS: 816-94-4

1,2-Distearoyl-sn-glycero-3-phosphorylcholine

Pureza: ≥98%

Peso molecular: 790.15g/mol

Ref: 54-BUP17227

1,2-Distearoyl-sn-glycero-3-phosphocholine

CAS: 816-94-4

Fórmula: C₄₄H₈₈NO₈P

Cor e Forma: White powder

Peso molecular: 790.15

Ref: 7W-GL9096

(R)-2,3-Bis(Stearoyloxy)Propyl (2-(TrimEthylammonio)Ethyl) Phosphate

CAS: 816-94-4

(R)-2,3-Bis(Stearoyloxy)Propyl (2-(TrimEthylammonio)Ethyl) Phosphate

Pureza: 99%

Peso molecular: 790.15g/mol

Ref: 54-OR1008465

1,2-Distearoyl-sn-Glycero-3-Phosphatidylcholine

CAS: 816-94-4

Fórmula: C44H88NO8P

Pureza: >98%

Cor e Forma: Solid

Peso molecular: 790.15

Ref: 48-37-1800

1,2-Distearoyl-sn-glycero-3-phosphocholine

CAS: 816-94-4

Fórmula: C₄₄H₈₈NO₈P

Pureza: 95%~99%

Peso molecular: 790.161

Ref: BP-BP2378

1,2-Distearoyl-sn-glycero-3-phosphorylcholine

CAS: 816-94-4

1,2-Distearoyl-sn-glycero-3-phosphorylcholine, a cylindrical lipid, is used to make liposomes and LNPs.

Fórmula: C₄₄H₈₈NO₈P

Pureza: 99.15% - 99.53%

Cor e Forma: Solid

Peso molecular: 790.15

Ref: TM-T9510

1,2-Distearoyl-sn-glycero-3-phosphocholine

CAS: 816-94-4

Fórmula: C₄₄H₈₈NO₈P

Peso molecular: 790.16

Ref: 4Z-C-5964

1,2-Distearoyl-sn-glycero-3-phosphocholine

CAS: 816-94-4

1,2-Distearoyl-sn-glycero-3-phosphocholine is an organic compound that can be used as a building block for the synthesis of more complex molecules. It has been shown to have antiplatelet properties and may be useful in the treatment of cardiovascular diseases. This chemical is also a useful intermediate for the production of pharmaceuticals or other chemicals. 1,2-Distearoyl-sn-glycero-3-phosphocholine can be obtained from natural sources and is not harmful to humans or animals when consumed.

Fórmula: C₄₄H₈₈NO₈P

Peso molecular: 790.17 g/mol

Ref: 3D-D-7850

(R)-2,3-BIS(STEAROYLOXY)PROPYL (2-(TRIMETHYLAMMONIO)ETHYL) PHOSPHATE

CAS: 816-94-4

Pureza: 98%

Peso molecular: 790.1610107

Ref: 10-F793317

1,2-Distearoyl-sn-glycero-3-phosphocholine

Produto Controlado

CAS: 816-94-4

Fórmula: C₄₄H₈₈NO₈P

Cor e Forma: Neat

Peso molecular: 790.145

Ref: TR-D493600

1,2-Distearoyl-sn-glycero-3-phosphocholine-d9

Produto Controlado

CAS: 816-94-4

Fórmula: C₄₄D₉H₇₉NO₈P

Cor e Forma: Neat

Peso molecular: 799.201

Ref: TR-D493602

DSPC

CAS: 816-94-4

1,2-Distearoyl-sn-glycero-3-phosphocholine (DSPC), also known as L-α-phosphatidylcholine distearoyl, is a neutral phospholipid with two saturated stearoyl chains (18:0) commonly used in the generation of artificial membranes such as lipid nanoparticles (LNP). DSPC is a formulation component for drugs as part of liposomal delivery systems, including for mRNA vaccines such as those used against COVID-19 (SARS-CoV-2).

Fórmula: C₄₄H₈₈NO₈P

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 790.15 g/mol

Ref: 3D-FP47180