CAS 82854-37-3

Equinacosídeo

Descrição:

Equinacosídeo é um composto fenólico derivado principalmente da planta Echinacea, particularmente da Echinacea purpurea. É classificado como um glicosídeo, consistindo em um grupo de ácido cafeico ligado a uma molécula de glicose. Equinacosídeo exibe uma variedade de atividades biológicas, incluindo efeitos antioxidantes, anti-inflamatórios e imunomoduladores, que contribuem ao seu uso na medicina herbal tradicional. O composto é conhecido por suas potenciais propriedades terapêuticas, particularmente na melhoria da função imunológica e no combate a infecções respiratórias. Equinacosídeo é solúvel em água e em solventes orgânicos, tornando-o versátil para várias aplicações em farmacêuticos e nutracêuticos. Sua estabilidade e biodisponibilidade são influenciadas por fatores como pH e temperatura. Além disso, a pesquisa continua a explorar seus mecanismos de ação e benefícios potenciais para a saúde e o bem-estar. Assim como muitos compostos naturais, a eficácia e segurança de Equinacosídeo podem variar com base na dosagem e nas condições de saúde individuais, exigindo mais estudos para entender completamente seu potencial terapêutico.

Fórmula: C₃₅H₄₆O₂₀

InChI: InChI=1/C35H46O20/c1-14-24(42)26(44)29(47)35(51-14)55-32-30(48)34(49-9-8-16-3-6-18(38)20(40)11-16)53-22(13-50-33-28(46)27(45)25(43)21(12-36)52-33)31(32)54-23(41)7-4-15-2-5-17(37)19(39)10-15/h2-7,10-11,14,21-22,24-40,42-48H,8-9,12-13H2,1H3/b7-4+/t14-,21+,22+,24-,25+,26+,27-,28+,29+,30+,31+,32+,33+,34+,35-/m0/s1

Chave InChI: InChIKey=FSBUXLDOLNLABB-WZJPPVJYSA-N

SMILES: O(C(C=CC1=CC(O)=C(O)C=C1)=O)[C@H]2[C@H](O[C@H]3[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O3)[C@@H](O)[C@H](OCCC4=CC(O)=C(O)C=C4)O[C@@H]2CO[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O

Sinónimos:

• (2E)-3-(3,4-Dihydroxyphényl)acrylate de (2R,3R,4R,5R,6R)-6-[2-(3,4-dihydroxyphényl)éthoxy]-5-hydroxy-2-({[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxyméthyl)tétrahydro-2H-pyran-2-yl]oxy}méthyl)-4-{[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-méthyltétrahydro-2H-pyran-2-yl]oxy}tétrahydro-2H-pyran-3-yle
• (2R,3R,4R,5R,6R)-6-[2-(3,4-Dihydroxyphenyl)ethoxy]-5-hydroxy-2-({[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}methyl)-4-{[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}tetrahydro-2H-pyran-3-yl (2E)-3-(3,4-dihydroxyphenyl)acrylate
• (2R,3R,4R,5R,6R)-6-[2-(3,4-Dihydroxyphenyl)ethoxy]-5-hydroxy-2-({[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}methyl)-4-{[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}tetrahydro-2H-pyran-3-yl-(2E)-3-(3,4-dihydroxyphenyl)acrylat
• 2-(3,4-Dihydroxyphenyl)ethyl 6-deoxy-alpha-L-mannopyranosyl-(1-> 3)-[beta-D-glucopyranosyl-(1-> 6)]-4-O-[(2E)-3-(3,4-dihydroxyphenyl)-2-propenoyl]-beta-D-glucopyranoside
• 2-(3,4-Dihydroxyphenyl)ethyl 6-deoxy-alpha-L-mannopyranosyl-(1-> 3)-[beta-D-glucopyranosyl-(1-> 6)]-4-O-[(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]-beta-D-glucopyranoside
• 6-Désoxy-alpha-L-mannopyranosyl-(1-> 3)-[bêta-D-glucopyranosyl-(1-> 6)]-4-O-[(2E)-3-(3,4-dihydroxyphényl)-2-propènan-1-oyl]-bêta-D-glucopyranoside de 2-(3,4-dihydroxyphényl)éthyle
• beta-D-glucopyranoside, 2-(3,4-dihydroxyphenyl)ethyl O-6-deoxy-alpha-L-mannopyranosyl-(1-> 3)-O-[beta-D-glucopyranosyl-(1-> 6)]-4-O-[(2E)-3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]-
• beta-D-glucopyranoside, 2-(3,4-dihydroxyphenyl)ethyl O-6-deoxy-alpha-L-mannopyranosyl-(1-> 3)-O-[beta-D-glucopyranosyl-(1-> 6)]-4-O-[(2E)-3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]-
• β-<span class="text-smallcaps">D</smallcap>-Glucopyranoside, 2-(3,4-dihydroxyphenyl)ethyl O-6-deoxy-α-<smallcap>L</smallcap>-mannopyranosyl-(1→3)-O-[β-<smallcap>D</span>-glucopyranosyl-(1→6)]-, 4-[3-(3,4-dihydroxyphenyl)-2-propenoate]
• Echinacoside
• β-D-Glucopyranoside, 2-(3,4-dihydroxyphenyl)ethyl O-6-deoxy-α-L-mannopyranosyl-(1→3)-O-[β-D-glucopyranosyl-(1→6)]-, 4-[3-(3,4-dihydroxyphenyl)-2-propenoate]
• (1-3)-o-(beta-d-glucopyranosyl-(1-6))-,4-(3-(3,4-dihydroxyphenyl)-2-propenoat
• Echicoside
• [(2R,3R,4R,5R,6R)-6-[2-(3,4-Dihydroxyphenyl)ethoxy]-5-hydroxy-2-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]-4-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl] (E)-3-(3,4-dihydroxyphenyl)
• ECHINACOSIDE 20% DESERTLIVING CISTANCHE P.E.
• Echinacoside, froM Cistanche deserticola Y.C.Ma
• Echinacoside/CH54339
• [(2R,3R,4R,5R,6R)-6-[2-(3,4-Dihydroxyphenyl)ethoxy]-5-hydroxy-2-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]-4-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl] (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate
• beta-d-e
• Cistanche tubulosa
• Echinacoside Standard
• ECHINACOSIDE(AHP)
• ECHINACOSIDE(AMERICAN HERBAL PHARMACOPOEIA)
• 2-(3,4-dihydroxyphenyl)ethylo-6-deoxy-alpha-l-mannopyranosyl-glucopyranosid
• Echinacoside, 98%, from Cistanche deserticola Y.C.Ma
• 2-(3,4-Dihydroxyphenyl)ethyl 3-O-(6-deoxy-α-L-mannopyranosyl)-6-O-β-D-glucopyranosyl-4-O-[3-(3,4-dihydroxyphenyl)propenoyl]-β-D-glucopyranoside
• Purpureaside C
• ECHINACOSIDE WITH HPLC

Echinacoside

CAS: 82854-37-3

Echinacoside analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Fórmula: C₃₅H₄₆O₂₀

Pureza: (HPLC) ≥98%

Cor e Forma: Powder

Peso molecular: 786.74

Ref: 11-4988S

Echinacoside

CAS: 82854-37-3

Other glycosides, natural or reproduced by synthesis, and their salts, ethers, esters and other derivatives

Fórmula: C₃₅H₄₆O₂₀

Cor e Forma: Off-White Powder

Peso molecular: 786.25824

Ref: 45-1231750

Echinacoside

CAS: 82854-37-3

Fórmula: C₃₅H₄₆O₂₀

Pureza: %

Cor e Forma: Solid

Peso molecular: 786.7277

Ref: IN-DA00G2TM

Echinacoside

CAS: 82854-37-3

Echinacoside

Pureza: 98%

Peso molecular: 786.73g/mol

Ref: 54-OR1024253

Echinacoside

CAS: 82854-37-3

Echinacoside

Pureza: ≥98%

Peso molecular: 786.73g/mol

Ref: 54-BUP00152

Echinacoside

CAS: 82854-37-3

Fórmula: C₃₅H₄₆O₂₀

Pureza: ≥ 98.0%

Cor e Forma: White off-white or beige powder

Peso molecular: 786.73

Ref: 7W-GL0233

Echinacoside

CAS: 82854-37-3

Echinacoside is a natural polyphenolic compound, has various kinds of pharmacological activities, such as anti-senescence, anti-hypoxia, anti-cancer, anti-osteoporosis, antioxidative, anti-inflammatory, neuroprotective, hepatoprotective, nitric oxide radical-scavenging and vasodilative ones. Echinacoside can improve the hematopoietic function of bone marrow in 5-FU-induced myelosuppression mice, it induces apoptotic cancer cell death by inhibiting the nucleotide pool sanitizing enzyme MTH1. Echinacoside inhibits cytochrome c release and caspase-3 activation caused by ensuing rotenone exposure via activating Trk-extracellular signal-regulated kinase (ERK) pathway in neuronal cells.

Fórmula: C₃₅H₄₆O₂₀

Pureza: 95%~99%

Peso molecular: 786.733

Ref: BP-BP0520

Echinacoside

CAS: 82854-37-3

Echinacoside: a polyphenol with anti-inflammatory, antioxidant, liver and nerve protection, NO scavenging, and vasodilation properties.

Fórmula: C₃₅H₄₆O₂₀

Pureza: 99.59% - >99.99%

Cor e Forma: White Crystal

Peso molecular: 786.73

Ref: TM-T1716

Echinacoside

CAS: 82854-37-3

Natural glycoside

Fórmula: C₃₅H₄₆O₂₀

Pureza: ≥ 95.0 % (HPLC)

Cor e Forma: Powder

Peso molecular: 786.74

Ref: 5G-89188

Echinacoside Ethanolate

CAS: 82854-37-3

Applications Echinacoside Ethanolate is a caffeic acid glycoside, known for its neuroprotective, antiinflammatory and anti-oxidative activities. Also an anti[proliferative towards hypoxia influenced pulmonary artery smooth muscle cells.
References Gai, X. et al.: J. Pharm. Sci., 126, 155 (2014);

Fórmula: C₃₅H₄₆O₂₀

Cor e Forma: Neat

Peso molecular: 786.73

Ref: TR-E325620

Echinacoside

CAS: 82854-37-3

Echinacoside is a caffeic acid derivative naturally found in plants, such as, Echinacea angustifolia DC. Echinacoside belongs to the class of phenylethanoid glycosides. In vitro studies have revealed the mode of action of echinacoside in breast cancer cells; echinacoside suppresses the Wnt/β-catenin signalling pathway exerting anticancer activity (Tang et al, 2020). Echinacoside has been reported as beneficial for human health in terms of neuroprotection, cardioprotectiony, anti-inflammatory, antioxidant and anti-osteoporotic activity (Liu, 2018).

Fórmula: C₃₅H₄₆O₂₀

Pureza: Min. 98 Area-%

Cor e Forma: Powder

Peso molecular: 786.74 g/mol

Ref: 3D-OE08287