CAS 82911-69-1

N-(9-Fluorenilmetoxicarboniloxi)succinimida

Descrição:

N-(9-Fluorenilmetoxicarboniloxi)succinimida, comumente referido como FMOC-succinimida, é um composto químico amplamente utilizado na síntese orgânica, particularmente na química de peptídeos. Serve como um grupo protetor para aminoácidos, permitindo reações seletivas sem interferir com outros grupos funcionais. A estrutura apresenta um moiety de succinimida ligado a um grupo 9-fluorenilmetoxicarbonila (FMOC), que é conhecido por sua estabilidade em condições básicas e facilidade de remoção em condições ácidas suaves. Este composto é tipicamente um sólido branco a off-white e é solúvel em solventes orgânicos como diclorometano e dimetilformamida. Suas aplicações se estendem além da síntese de peptídeos para incluir uso em várias reações de acoplamento e como um reagente em transformações orgânicas. O grupo FMOC é favorecido por sua capacidade de fornecer um ambiente protetor estável enquanto facilita reações subsequentes, tornando-se uma ferramenta valiosa na química orgânica sintética. Precauções de segurança devem ser observadas ao manusear este composto, pois pode representar riscos à saúde se inalado ou ingerido.

Fórmula: C₁₉H₁₅NO₅

InChI: InChI=1/C19H15NO5/c21-17-9-10-18(22)20(17)25-19(23)24-11-16-14-7-3-1-5-12(14)13-6-2-4-8-15(13)16/h1-8,16H,9-11H2

Chave InChI: InChIKey=WMSUFWLPZLCIHP-UHFFFAOYSA-N

SMILES: C(OC(ON1C(=O)CCC1=O)=O)C2C=3C(C=4C2=CC=CC4)=CC=CC3

Sinónimos:

• (2,5-Dioxopyrrolidin-1-yl) 9H-fluoren-9-ylmethyl carbonate
• (9H-Fluoren-9-yl)methyl succinimidyl carbonate
• (Fluorenylmethoxycarbonyl)hydroxysuccinimide ester
• 1-(9H-Fluorenylmethoxycarbonyloxy)-2,5-pyrrolidinedione
• 1-[[[(9H-Fluoren-9-yl)methoxy]carbonyl]oxy]pyrrolidine-2,5-dione
• 1-{[(9H-fluoren-9-ylmethoxy)carbonyl]oxy}pyrrolidine-2,5-dione
• 2,5-Dioxopyrrolidin-1-yl (9H-fluoren-9-yl)methyl carbonate
• 2,5-Pyrrolidinedione, 1-[[(9H-fluoren-9-ylmethoxy)carbonyl]oxy]-
• 9-Fluorenylmethyl N-succinimidyl carbonate
• 9-Fluorenylmethyl succinimidyl carbonate
• 9-Fluorenylmethyl-N-hydroxysuccinimide
• Carbonic acid, 2,5-dioxo-1-pyrrolidinyl 9H-fluoren-9-ylmethyl ester
• FMOC-ONSu
• Fluorenylmethoxycarbonyl N-hydroxysuccinimide
• Fmoc-N-hydroxysuccinimide
• Fmoc-N-hydroxysuccinimide ester
• Fmoc-Osu
• N-(9-Fluorenylmethoxy Carbonyloxy) succinimide
• N-(9-Fluorenylmethyloxycarbonyl) oxysuccinimide
• N-(9H-Fluoren-2-ylmethoxycarbonyloxy)succinimide
• N-(9H-Fluoren-9-ylmethoxycarbonyloxy)succinimide
• N-Fmoc-succinimide
• Succinimidyl (9-fluorenyl)methyl carbonate
• N-(9-FluorenylmethoxyCarbonyloxy) Succinimide
• N-(9-fluorenylmethoxycarbonyloxy)-succinimide
• N-(9-Fluorenylmethoxycarbonyloxy)succinimide
• N-(9-FLUORENYLMETHOXYCARBONYL)SUCCINIMIDE
• 9-FLUORENYLMETHYLOXYCARBONYL-N-HYDROXYSUCCINIMIDE
• 9-FLUORENYLMETHYL N-HYDROXYSUCCINIMIDYL CARBONATE
• CARBONIC ACID FLUORENYLMETHYL SUCCIN-N-YL-ESTER
• N-(9-FLUORENEMETHOXYCARBONYLOXY)-SUCCINIMIDE
• CARBONIC ACID 2,5-DIOXO-PYRROLIDIN-1-YL ESTER 9H-FLUOREN-9-YLMETHYL ESTER
• N-(9-FLUORENYLMETHYLOXYCARBONYLOXY)-SUCCINIMIDE
• FMOC-SU
• FLUORENYLMETHYL SUCCINIMIDYL CARBONATE
• 9-FLUORENMETHYL SUCCINIMIDYL CARBONATE

N-(9-Fluorenylmethoxycarbonyloxy)succinimide, 98%

CAS: 82911-69-1

N-(9-Fluorenylmethoxycarbonyloxy)succinimide is the most efficient reagent for the selective preparation of N-(9-fluorenylmethoxycarbonyl) derivatives of hydroxy-amino acids. Dipeptide formation is lower than with the chloroformate, Fmoc-Cl. It is also employed in the synthesis of glycopeptides. Thi

Fórmula: C₁₉H₁₅NO₅

Pureza: 98%

Cor e Forma: White, Powder

Peso molecular: 337.33

Ref: 02-A13143

Fmoc-ONSU

CAS: 82911-69-1

Fórmula: C₁₉H₁₅NO₅

Pureza: 97%

Cor e Forma: Powder or Crystalline Powder

Peso molecular: 337.331

Ref: 10-F011742

Fmoc-OSu

CAS: 82911-69-1

Most efficient reagent for the selective preparation of Fmoc-derivatives of hydroxy amino acids in high yield. The advantage of Fmoc-OSu is that little or no oligopeptides are formed when amino acid derivatives are prepared. The use of this reagent in the synthesis of glycopeptides has been reported as well.

Fórmula: C₁₉H₁₅NO₅

Pureza: 99.8%

Cor e Forma: White

Peso molecular: 337.33

Ref: 01-4006805

N-(9-Fluorenylmethoxycarbonyloxy)succinimide

CAS: 82911-69-1

Fórmula: C₁₉H₁₅NO₅

Pureza: 97%

Cor e Forma: Solid

Peso molecular: 337.3261

Ref: IN-DA0034XN

Fmoc N-hydroxysuccinimide ester

CAS: 82911-69-1

Fórmula: C₁₉H₁₅NO₅

Pureza: ≥ 98.0%

Cor e Forma: White to off-white crystalline powder

Peso molecular: 337.34

Ref: 7W-GM5706

N-[(9H-Fluoren-9-ylmethoxy)carbonyloxy]succinimide

CAS: 82911-69-1

Fórmula: C₁₉H₁₅NO₅

Pureza: >98.0%(T)(HPLC)

Cor e Forma: White to Almost white powder to crystal

Peso molecular: 337.33

Ref: 3B-F0239

1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}oxy)pyrrolidine-2,5-dione

CAS: 82911-69-1

1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}oxy)pyrrolidine-2,5-dione

Fórmula: C₁₉H₁₅NO₅

Pureza: ≥95%

Cor e Forma: white solid

Peso molecular: 337.32609g/mol

Ref: 54-OR18352

Fmoc-Osu (N-Fmoc-succinimide)

CAS: 82911-69-1

Fórmula: C₁₉H₁₅NO₅

Peso molecular: 337.33

Ref: 4Z-S-131003

Fmoc N-Hydroxysuccinimide Ester

CAS: 82911-69-1

Stability Moisture Sensitive
Applications Used in conjunction with Isothiocyanate to conduct partial Edman Degradation on biologically active peptides.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Heidenreich, O., et al.: J. Biol. Chem., 269, 2131 (1994), Kothe, U., et al.: Anal. Biochem., 356, 148 (2006), Thakkar, A., et al.: Anal. Chem., 78, 5935 (2006),

Fórmula: C₁₉H₁₅NO₅

Cor e Forma: Neat

Peso molecular: 337.33

Ref: TR-F634000

Fmoc-OSu

CAS: 82911-69-1

Fmoc-OSu is a matrix that can be used as an absorption enhancer in biological and biochemical studies. The ester hydrochloride form of Fmoc-OSu is soluble in water and methanol, but not in organic solvents such as chloroform or ether. Fmoc-OSu is also a fluorescent derivative that can be used to label glycan structures in primary cells. The reaction solution with anhydrous sodium carbonate and glycan produces a cyclic peptide. This reaction is carried out at room temperature with analytical methods using a spectrophotometer or high performance liquid chromatography (HPLC).

Fórmula: C₁₉H₁₅NO₅

Pureza: Min. 95%

Cor e Forma: White Powder

Peso molecular: 337.33 g/mol

Ref: 3D-FF10663

FMOC-OSu extrapure AR, 99%

CAS: 82911-69-1

Fórmula: C₁₉H₁₅NO₅

Pureza: min. 99.0%

Cor e Forma: White to off - white, Powder

Peso molecular: 337.33

Ref: SR-79235

Fmoc-OSu

CAS: 82911-69-1

Fmoc-OSu is a synthetic amino acid that is used in the synthesis of peptides and other biomolecules. It can be synthesized by solid-phase peptide synthesis using Fmoc chemistry, which involves an acid-labile protecting group. Fmoc-OSu has been shown to inhibit cancer cell growth, although its mechanism is not known.
Fmoc-OSu has been shown to have anti-inflammatory effects by inhibiting the proinflammatory cytokine TNFα.
Fmoc-OSu has also been shown to have glycan binding properties, which may be due to its ability to bind with sialic acid residues on glycoproteins or glycolipids.

Fórmula: C₁₉H₁₅NO₅

Pureza: Min. 98.0 Area-%

Peso molecular: 337.33 g/mol

Ref: 3D-KFS-1042-PI