CAS 83002-04-4

5-(1,1-Dimetilheptil)-2-[(1R,2R,5R)-5-hidroxi-2-(3-hidroxipropil)cicloexil]fenol

Descrição:

A substância química conhecida como 5-(1,1-Dimetilheptil)-2-[(1R,2R,5R)-5-hidroxi-2-(3-hidroxipropil)cicloexil]fenol, com o número CAS 83002-04-4, é um composto sintético reconhecido principalmente por sua aplicação no campo da pesquisa de canabinoides. Este composto apresenta uma estrutura molecular complexa que inclui um grupo fenólico e um moiety de ciclohexila, que contribuem para sua potencial atividade biológica. É caracterizado por sua natureza hidrofóbica devido à presença de longas cadeias alquílicas, o que pode influenciar sua solubilidade e interação com membranas biológicas. A estereoquímica indicada pela configuração (1R,2R,5R) sugere arranjos espaciais específicos que podem afetar as propriedades farmacológicas do composto. Como um análogo de canabinoide, pode interagir com os receptores de canabinoides no corpo, potencialmente influenciando vários processos fisiológicos. No entanto, estudos detalhados são necessários para entender completamente sua eficácia, segurança e potenciais aplicações terapêuticas.

Fórmula: C₂₄H₄₀O₃

InChI: InChI=1S/C24H40O3/c1-4-5-6-7-14-24(2,3)19-11-13-21(23(27)16-19)22-17-20(26)12-10-18(22)9-8-15-25/h11,13,16,18,20,22,25-27H,4-10,12,14-15,17H2,1-3H3/t18-,20-,22-/m1/s1

Chave InChI: InChIKey=YNZFFALZMRAPHQ-SYYKKAFVSA-N

SMILES: C(CCO)[C@H]1[C@@H](C[C@H](O)CC1)C2=C(O)C=C(C(CCCCCC)(C)C)C=C2

Sinónimos:

• (-)-Cp 55940
• 2-[(1S,2R,5S)-5-hydroxy-2-(3-hydroxypropyl)cyclohexyl]-5-(2-methyloctan-2-yl)phenol
• 5-(1,1-Dimethylheptyl)-2-[(1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohexyl]phenol
• 5-(1,1-dimethylheptyl)-2-[(1S,2R,5S)-5-hydroxy-2-(3-hydroxypropyl)cyclohexyl]phenol
• Phenol, 5-(1,1-dimethylheptyl)-2-[5-hydroxy-2-(3-hydroxypropyl)cyclohexyl]-, (1α,2β,5α)-(-)-
• phenol, 5-(1,1-dimethylheptyl)-2-[(1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohexyl]-
• phenol, 5-(1,1-dimethylheptyl)-2-[(1S,2R,5S)-5-hydroxy-2-(3-hydroxypropyl)cyclohexyl]-

CP-55940

CAS: 83002-04-4

Fórmula: C₂₄H₄₀O₃

Peso molecular: 376.57

Ref: 7W-GL0738

(-)-CP 55,940 (10 mg/mL in methanol)

Produto Controlado

CAS: 83002-04-4

Applications CP 55,940 is a cannabinoid agonist which is considerably more potent than Δ9-THC in both behavioral tests and receptor binding assays. Displays high and roughly equal affinity for both central and peripheral cannabinoid receptors (Ki = 0.6 - 5.0 and 0.7 - 2.6 nM at CB1 and CB2 respectively; EC50 values are 0.2, 0.3 and 5 nM at CB1, CB2 and GRP55 respectively).Controlled substance. Synthetic Cannabinoids
References Wiley, et al.: Neuropharmacology, 34, 669 (1995); Griffin, et al.: J. Pharmacol. Exp. Ther., 285, 553 (1998); Thomas, et al.: J. Pharmacol. Exp. Ther., 285, 285 (1998); Ryberg, et al.: Br. J. Pharmacol., 152, 1092 (2007);

Fórmula: C₂₄H₄₀O₃

Cor e Forma: Single Solution

Peso molecular: 376.57

Ref: TR-C781410

CP 55940

Produto Controlado

CAS: 83002-04-4

CP 55940 is a cannabinoid receptor agonist that inhibits acetylcholine release in the brain and has been shown to cause neuronal death. CP 55940 binds to the α7 nicotinic acetylcholine receptor, which is important for memory and learning. The binding of this drug causes an increase in guanine nucleotide-binding protein (G protein) activity by reducing the rate of GTP hydrolysis, leading to inhibition of adenylyl cyclase activity and subsequent decrease in cAMP levels. CP 55940 has significant up-regulation of toll-like receptors following exposure, which leads to an increased immune response. This drug can also cause bowel disease or side effects such as seizures and psychotic symptoms. CP 55940 can interact with other drugs, including cannabinoids that may lead to serious side effects.

Fórmula: C₂₄H₄₀O₃

Pureza: Min. 95%

Peso molecular: 376.57 g/mol

Ref: 3D-FD146910