CAS 834-28-6

cloridrato de fenformina

Descrição:

cloridrato de fenformina é um composto farmacêutico utilizado principalmente como agente antidiabético, pertencente à classe de medicamentos biguanidas. É caracterizado por sua capacidade de reduzir os níveis de glicose no sangue, melhorando a sensibilidade à insulina e reduzindo a produção hepática de glicose. O composto é tipicamente apresentado como um pó cristalino branco a off-white, que é solúvel em água e exibe um sabor ligeiramente amargo. Sua estrutura química inclui um grupo fenila, que contribui para suas propriedades farmacológicas. cloridrato de fenformina tem sido associado a efeitos colaterais gastrointestinais e, em alguns casos, acidose láctica, levando à sua retirada do mercado em muitos países. Apesar de seu uso histórico, é importante notar que seu perfil de segurança levantou preocupações, levando ao desenvolvimento de medicamentos alternativos com melhor segurança e eficácia. Assim como com qualquer agente farmacêutico, a dosagem adequada e o monitoramento são essenciais para minimizar riscos e maximizar benefícios terapêuticos.

Fórmula: C₁₀H₁₆ClN₅

InChI: InChI=1/C10H15N5.ClH/c11-9(12)15-10(13)14-7-6-8-4-2-1-3-5-8;/h1-5H,6-7H2,(H6,11,12,13,14,15);1H

Chave InChI: InChIKey=YSUCWSWKRIOILX-UHFFFAOYSA-N

SMILES: C(CNC(NC(=N)N)=N)C1=CC=CC=C1.Cl

Sinónimos:

• 1-(2-Phenylethyl)biguanide hydrochloride
• 1-(Diaminomethylidene)-2-(2-Phenylethyl)Guanidine Hydrochloride (1:1)
• 1-Phenethylbiguanide hydrochloride
• 1-β-Phenylethylbiguanide hydrochloride
• Azucaps
• Biguanide, 1-phenethyl-, monohydrochloride
• Dbi-Td
• Debeone DT
• Debinyl
• Dibein
• Dipar
• Feguanide
• Glucopostin
• Imidodicarbonimidic diamide, N-(2-phenylethyl)-, hydrochloride (1:1)
• Imidodicarbonimidic diamide, N-(2-phenylethyl)-, monohydrochloride
• Insoral
• Lentobetic
• Meltrol
• N-Phenethylbiguanide hydrochloride
• Normoglucina
• N′-β-Phenylethylbiguanide-hydrochloride
• Phenethylbiguanide hydrochloride
• Phenformin Hcl
• Phenformine HCL
• α-Phenethylbiguanide hydrochloride
• n-beta-phenylethylbiguanidehydrochloride
• 1-fenetilbiguanidecloridrato
• n’-beta-phenethylbiguanidehydrochloride
• 1-phenethyl-biguanidhydrochloride
• phenoforminehydrochloride
• phenforminhclno.9113
• PHENFORMIN HYDROCHLORIDE
• n-(2-phenylethyl)-imidodicarbonimidicdiamidmonohydrochloride
• usafvi-6
• 1-phenethyl-biguanidmonohydrochloride
• PHENFORMINI HYDROCHLORIDE
• Insora
• 1-phenylaethylbiguanidhydrochlorid

Phenformin Hydrochloride

CAS: 834-28-6

Cor e Forma: Neat

Ref: 61-FOR1574.00

Imidodicarbonimidic diamide, N-(2-phenylethyl)-, monohydrochloride

CAS: 834-28-6

Fórmula: C₁₀H₁₆ClN₅

Pureza: 97%

Cor e Forma: Solid

Peso molecular: 241.7205

Ref: IN-DA00IDAP

Phenformin hydrochloride

CAS: 834-28-6

Phenformin hydrochloride (Phenformin HCl) is an agent belonging to the biguanide class of antidiabetics with antihyperglycemic activity.

Fórmula: C₁₀H₁₆ClN₅

Pureza: 97.11% - 99.80%

Cor e Forma: Lactic Acidosis

Peso molecular: 241.72

Ref: TM-T1453

Phenformin hydrochloride

CAS: 834-28-6

Phenformin hydrochloride

Pureza: ≥95%

Peso molecular: 241.72g/mol

Ref: 54-BUP19681

Phenformin Hydrochloride

CAS: 834-28-6

Phenformin Hydrochloride

Pureza: 98%

Peso molecular: 241.72g/mol

Ref: 54-OR1014623

Phenformin HCl

CAS: 834-28-6

Fórmula: C₁₀H₁₅N₅·HCl

Cor e Forma: White To Off-White Solid

Peso molecular: 205.27 36.46

Ref: 4Z-P-751

Phenformin Hydrochloride

Produto Controlado

CAS: 834-28-6

Fórmula: C₁₀H₁₅N₅·ClH

Cor e Forma: Neat

Peso molecular: 241.72

Ref: 86-MM1574.00

Phenformin hydrochloride

CAS: 834-28-6

Fórmula: C₁₀H₁₅N₅·ClH

Cor e Forma: Neat

Peso molecular: 241.72

Ref: 04-C16004500

Phenformin-d5 Hydrochloride

Produto Controlado

CAS: 834-28-6

Applications Isotope labelled Phenformin It is an anti-diabetic drug from the biguanide class.
References Moody, J.E., Anal. Profiles Drug Subs., 4, 319 (1975),

Fórmula: C₁₀D₅H₁₀N₅·ClH

Cor e Forma: Neat

Peso molecular: 210.29+36.46x

Ref: TR-P296902

Phenformin Hydrochloride

CAS: 834-28-6

Applications It is an anti-diabetic drug from the biguanide class.
References Moody, J.E., Anal. Profiles Drug Subs., 4, 319 (1975),

Fórmula: C₁₀H₁₅N₅·ClH

Cor e Forma: Neat

Peso molecular: 241.72

Ref: TR-P296900

N-(2-phenylethyl)imidodicarbonimidic diamide hydrochloride

CAS: 834-28-6

Fórmula: C₁₀H₁₆ClN₅

Pureza: ≥97%

Cor e Forma: Solid

Peso molecular: 241.72

Ref: 10-F375298

Phenformin Hydrochloride

CAS: 834-28-6

Fórmula: C₁₀H₁₅N₅HCl

Peso molecular: 205.27 : 36.46

Ref: ST-EA-CP-P236000

Phenformin hydrochloride

CAS: 834-28-6

Phenformin hydrochloride is a phenformin derivative that is used as an oral hypoglycemic. It has been shown to inhibit the synthesis of fatty acids in the liver and to reduce the size of lipid droplets, which are a hallmark of hepatic steatosis. Phenformin hydrochloride also inhibits the polymerase chain reaction and mitochondrial membrane potential, which results in reduced oxidative stress and apoptosis. This drug has been shown to have anti-infectious effects against infectious diseases such as typhoid fever, tuberculosis, and malaria. Phenformin hydrochloride may also be carcinogenic, due to its ability to induce skin cancer in mice with a genetic predisposition for this type of cancer. The drug should not be administered to patients with metabolic disorders or patients who are receiving chemotherapy agents that affect cell proliferation because it can exacerbate these conditions.

Fórmula: C₁₀H₁₆ClN₅

Pureza: Min. 95 Area-%

Cor e Forma: Powder

Peso molecular: 241.72 g/mol

Ref: 3D-FP26876