CAS 84-36-6

Sirocingopina

Descrição:

Sirocingopina é um composto orgânico classificado como um alcaloide, derivado principalmente da espécie vegetal *Sirocingopina* e plantas relacionadas. É conhecido por sua complexidade estrutural, apresentando uma estrutura bicíclica que inclui um anel de piperidina. O composto exibe uma variedade de atividades biológicas, incluindo potenciais efeitos analgésicos e antihipertensivos, tornando-o de interesse na pesquisa farmacológica. Sirocingopina é tipicamente caracterizado por sua solubilidade em solventes orgânicos, enquanto sua solubilidade em água é limitada. O composto tem um peso molecular relativamente baixo e é frequentemente estudado por suas interações com vários alvos biológicos, incluindo receptores e enzimas. Suas propriedades químicas, como ponto de fusão e ponto de ebulição, são influenciadas por sua estrutura molecular e grupos funcionais. Assim como muitos alcaloides, Sirocingopina também pode exibir propriedades quirais, levando a diferentes atividades biológicas dependendo de sua estereoquímica. No geral, Sirocingopina representa uma área significativa de estudo em química medicinal e pesquisa de produtos naturais.

Fórmula: C₃₅H₄₂N₂O₁₁

InChI: InChI=1S/C35H42N2O11/c1-7-46-35(40)48-31-26(42-3)12-18(13-27(31)43-4)33(38)47-28-14-19-17-37-11-10-22-21-9-8-20(41-2)15-24(21)36-30(22)25(37)16-23(19)29(32(28)44-5)34(39)45-6/h8-9,12-13,15,19,23,25,28-29,32,36H,7,10-11,14,16-17H2,1-6H3/t19-,23+,25-,28-,29+,32+/m1/s1

Chave InChI: InChIKey=ZCDNRPPFBQDQHR-SSYATKPKSA-N

SMILES: C(OC)(=O)[C@H]1[C@]2(C[C@@]3(C4=C(C=5C(N4)=CC(OC)=CC5)CCN3C[C@]2(C[C@@H](OC(=O)C6=CC(OC)=C(OC(OCC)=O)C(OC)=C6)[C@@H]1OC)[H])[H])[H]

Sinónimos:

• (1S,2R,3R,4aS,13bR,14aS)-3-({4-[(éthoxycarbonyl)oxy]-3,5-diméthoxybenzoyl}oxy)-2,11-diméthoxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodécahydroindolo[2',3':3,4]pyrido[1,2-b]isoquinoléine-1-carboxylate de méthyle
• (3Bêta,16Bêta,17Alpha,18Bêta,20Alpha)-18-({4-[(Éthoxycarbonyl)Oxy]-3,5-Diméthoxybenzoyl}Oxy)-11,17-Diméthoxyyohimban-16-Carboxylate De Méthyle
• (3b,16b,17a,18b,20a)-18-[[4-[(Ethoxycarbonyl)oxy]-3,5-dimethoxybenzoyl]oxy]-11,17-dimethoxyyohimban-16-carboxylic Acid Methyl Ester
• 3β,20α-Yohimban-16β-carboxylic acid, 18β-hydroxy-11,17α-dimethoxy-, methyl ester, 4-hydroxy-3,5-dimethoxybenzoate (ester) ethyl carbonate (ester)
• Carbethoxysyringoyl Methyl Reserpate
• Carbethoxysyringoyl methylreserpate
• Hf 41T
• Isotense
• Londomin
• Methyl (1S,2R,3R,4aS,13bR,14aS)-3-({4-[(ethoxycarbonyl)oxy]-3,5-dimethoxybenzoyl}oxy)-2,11-dimethoxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydroindolo[2',3':3,4]pyrido[1,2-b]isoquinoline-1-carboxylate
• Methyl (3Beta,16Beta,17Alpha,18Beta,20Alpha)-18-({[4-{[(Ethyloxy)Carbonyl]Oxy}-3,5-Bis(Methyloxy)Phenyl]Carbonyl}Oxy)-11,17-Bis(Methyloxy)Yohimban-16-Carboxylate
• Methyl (3Beta,16Beta,17Alpha,18Beta,20Alpha)-18-[({4-[(Ethoxycarbonyl)Oxy]-3,5-Dimethoxyphenyl}Carbonyl)Oxy]-11,17-Dimethoxyyohimban-16-Carboxylate
• Methyl (3beta,16beta,17alpha,18beta,20alpha)-18-({4-[(ethoxycarbonyl)oxy]-3,5-dimethoxybenzoyl}oxy)-11,17-dimethoxyyohimban-16-carboxylate
• Methyl carbethoxysyringoyl reserpate
• Methyl reserpate ester of syringic acid ethyl carbonate
• Methyl-(1S,2R,3R,4aS,13bR,14aS)-3-({4-[(ethoxycarbonyl)oxy]-3,5-dimethoxybenzoyl}oxy)-2,11-dimethoxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydroindolo[2',3':3,4]pyrido[1,2-b]isochinolin-1-carboxylat
• NSC 77030
• Raunova
• Reserpic acid, methyl ester, ester with syringic acid, ethyl carbonate
• Seniramin
• Singoserp
• Siringina
• Sml 1908
• Su 3118
• Syringic acid ethyl carbonate ester with methyl reserpate
• Syringopine
• Syrosingopin

Syrosingopine

CAS: 84-36-6

Syrosingopine analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.

Fórmula: C₃₅H₄₂N₂O₁₁

Pureza: (HPLC) ≥90%

Cor e Forma: Powder

Peso molecular: 666.73

Ref: 11-1691

Syrosingopine

CAS: 84-36-6

Syrosingopine

Pureza: ≥98%

Peso molecular: 666.71g/mol

Ref: 54-BUP07583

Syrosingopine

CAS: 84-36-6

Syrosingopine is a dual inhibitor of MCT1 and MCT4, 60 times more potent against MCT4, preventing lactate and H+ efflux.Cost-effective and quality-assured.

Fórmula: C₃₅H₄₂N₂O₁₁

Pureza: 99.25% - 99.78%

Cor e Forma: Solid

Peso molecular: 666.71

Ref: TM-TN2252

Syrosingopine

Produto Controlado

CAS: 84-36-6

Applications Syrosingopine (CAS# 84-36-6) is a pharmaceutical used to treat hypertension.
References Woods, J. W.; et al.: Journal of Clinical Investigation, 39, 1813 (1960).

Fórmula: C₃₅H₄₂N₂O₁₁

Pureza: >90%

Cor e Forma: Neat

Peso molecular: 666.71

Ref: TR-S920068

Syrosingopine

CAS: 84-36-6

Inhibitor of vesicular monoamine transporters with anti-hypertensive properties. Syrosingopine is also inhibitor of monocarboxylate transporters MCT1 and MCT4 and has 60-fold higher potency on MCT4. Syrosingopine inhibits lactate export from cells, causing glycolytic blockade, ATP depletion and cell death. Syrosingopine was shown to sensitise cancer cells to metformin treatment and potentiate its anti-cancer activity.

Fórmula: C₃₅H₄₂N₂O₁₁

Pureza: Min. 90 Area-%

Cor e Forma: White Powder

Peso molecular: 666.71 g/mol

Ref: 3D-FS65931

Syrosingopine - Bio-X ™

CAS: 84-36-6

Inhibitor of vesicular monoamine transporters with anti-hypertensive properties. Syrosingopine is also inhibitor of monocarboxylate transporters MCT1 and MCT4 and has 60-fold higher potency on MCT4. Syrosingopine inhibits lactate export from cells, causing glycolytic blockade, ATP depletion and cell death. Syrosingopine was shown to sensitise cancer cells to metformin treatment and potentiate its anti-cancer activity.

Fórmula: C₃₅H₄₂N₂O₁₁

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 666.72 g/mol

Ref: 3D-BS300129

SYROSINGOPINE

CAS: 84-36-6

Fórmula: C₃₅H₄₂N₂O₁₁

Pureza: %

Cor e Forma: Solid

Peso molecular: 666.7148

Ref: IN-DA00G2SK

Syrosingopine

CAS: 84-36-6

Cor e Forma: Neat

Ref: 61-FOR1970.00