CAS 84000-11-3

N-[(9H-Fluoren-9-ilmetoxi)carbonil]-N-metil-L-valina

Descrição:

N-[(9H-Fluoren-9-ilmetoxi)carbonil]-N-metil-L-valina, comumente referido como Fmoc-N-metil-L-valina, é um composto químico amplamente utilizado na síntese de peptídeos como um grupo protetor para aminoácidos. O grupo Fmoc, derivado de fluorenilmetoxicarbonila, fornece estabilidade durante o processo de síntese e pode ser facilmente removido em condições básicas, permitindo reações adicionais. Este composto apresenta um resíduo de valina, que é um aminoácido essencial conhecido por suas propriedades hidrofóbicas, contribuindo para as características gerais dos peptídeos nos quais está incorporado. A presença do grupo N-metil aumenta o volume estérico e pode influenciar a conformação dos peptídeos resultantes. Fmoc-N-metil-L-valina é tipicamente utilizado na síntese de peptídeos em fase sólida (SPPS), onde ajuda na montagem seletiva de cadeias peptídicas. Sua solubilidade em solventes orgânicos e estabilidade sob várias condições de reação o tornam um reagente valioso no campo da química orgânica e medicinal. Assim como muitas substâncias químicas, o manuseio adequado e as precauções de segurança são essenciais devido aos perigos potenciais associados ao seu uso.

Fórmula: C₂₁H₂₃NO₄

InChI: InChI=1/C21H23NO4/c1-13(2)19(20(23)24)22(3)21(25)26-12-18-16-10-6-4-8-14(16)15-9-5-7-11-17(15)18/h4-11,13,18-19H,12H2,1-3H3,(H,23,24)/t19-/m0/s1

Chave InChI: InChIKey=YCXXXPZNQXXRIG-IBGZPJMESA-N

SMILES: C(OC(N([C@@H](C(C)C)C(O)=O)C)=O)C1C=2C(C=3C1=CC=CC3)=CC=CC2

Sinónimos:

• (2S)-2-([[(9H-Fluoren-9-yl)methoxy]carbonyl](methyl)amino)-3-methylbutanoic acid
• (2S)-2-[9H-Fluoren-9-ylmethoxycarbonyl(methyl)amino]-3-methylbutanoic acid
• <span class="text-smallcaps">L</span>-Valine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-methyl-
• Fmoc-N-Me-Val-OH
• N-(9-Fluorenylmethoxycarbonyl)-N-methylvaline
• N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-methyl-<span class="text-smallcaps">L</span>-valine
• N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-methyl-L-valine
• N-alpha-(9-fluorenylmethyloxycarbonyl)-N-alpha-Methyl-L-valine
• L-Valine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-methyl-
• FMOC-N-ME-VAL 98.5+%
• FMOC-L-MEVAL-OH
• FMOC-N-METHYL-L-VALINE
• FMOC-N-ALPHA-METHYL-L-VALINE
• FMOC-MEVAL-OH
• FMOC-N-ME-L-VAL-OH
• FMOC-N-ME-VALINE
• N-(9-Fluorenylmethyloxycarbonyl)-N-methyl-L-valine
• N-ALPHA(9-FLUORENYLMETHOXYCARBONYL)-N-ALPHA-METHYL-L-VALINE

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-methyl-L-valine

CAS: 84000-11-3

Fórmula: C₂₁H₂₃NO₄

Pureza: >98.0%(T)(HPLC)

Cor e Forma: White to Almost white powder to crystal

Peso molecular: 353.42

Ref: 3B-F1165

N-Fmoc-N-methyl-L-valine, 95%

CAS: 84000-11-3

N-Fmoc-N-methyl-L-valine is used as enzyme substrates and reagents, culture media additives, dyes, stains and indicators. It is also involved in the preparation of N-methylated peptides. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some docu

Fórmula: C₂₁H₂₃NO₄

Pureza: 95%

Peso molecular: 353.42

Ref: 02-H63671

Fmoc-N-Me-Val-OH

CAS: 84000-11-3

The acid fluoride of this sterically hindered amino acid could be coupled to N-methylated amino acids in HFIP at 55°C.

Fórmula: C₂₁H₂₃NO₄

Pureza: 99.7%

Cor e Forma: White

Peso molecular: 353.42

Ref: 01-4009586

Fmoc-N-Me-Val-OH

CAS: 84000-11-3

Fórmula: C₂₁H₂₃NO₄

Pureza: 97%

Cor e Forma: Solid

Peso molecular: 353.4116

Ref: IN-DA005235

Fmoc-N-Me-Val-OH

CAS: 84000-11-3

Fórmula: C₂₁H₂₃NO₄

Pureza: (HPLC) ≥ 98.0%

Cor e Forma: White to light beige powder

Peso molecular: 353.41

Ref: 7W-GM1535

Fmoc-N-methyl-L-valine

CAS: 84000-11-3

Fmoc-N-methyl-L-valine

Fórmula: C₂₁H₂₃NO₄

Pureza: 98%

Cor e Forma: white powder

Peso molecular: 353.41g/mol

Ref: 54-OR960386

Fmoc-N-Me-Val-OH

CAS: 84000-11-3

Fmoc-N-Me-Val-OH is a modified peptide.

Fórmula: C₂₁H₂₃NO₄

Cor e Forma: White Powder

Peso molecular: 353.41

Ref: TM-T19325

Fmoc-N-Me-Val-OH

CAS: 84000-11-3

M03379 - Fmoc-N-Me-Val-OH

Fórmula: C₂₁H₂₃NO₄

Pureza: 97%

Cor e Forma: Solid, Beige powder

Peso molecular: 353.418

Ref: 10-M03379

Fmoc-N-methyl-L-valine

CAS: 84000-11-3

Fmoc-N-methyl-L-valine is a synthetic immunosuppressant that acts by inhibiting the production of cytokines and other inflammatory mediators. It binds to the enzyme cyclooxygenase, which is involved in the synthesis of prostaglandins and thromboxanes. Fmoc-N-methyl-L-valine has been shown to be effective against gram-positive bacteria. This compound also inhibits xanthine oxidase and may act as an analog for azathioprine, which is used in the treatment of autoimmune diseases such as rheumatoid arthritis. The reaction mechanism for this compound is not well understood but appears to involve a nucleophilic attack on a benzoquinoneiminium cation formed from the attack on an electron deficient benzene ring with a triphosgene electrophile.

Fórmula: C₂₁H₂₃NO₄

Pureza: Min. 95%

Peso molecular: 353.41 g/mol

Ref: 3D-FF32984