CAS 84676-89-1

Astragalosídeo II

Descrição:

Astragalosídeo II, com o número CAS 84676-89-1, é um glicosídeo natural derivado principalmente da raiz de Astragalus membranaceus, uma planta comumente utilizada na medicina tradicional. Este composto é caracterizado por sua composição estrutural, que inclui uma porção de açúcar ligada a um aglicona esteroidal. Astragalosídeo II é conhecido por suas potenciais propriedades farmacológicas, incluindo efeitos imunomoduladores, anti-inflamatórios e antioxidantes. Tem sido estudado por seu papel em melhorar a função imunológica e promover a saúde celular. Além disso, pesquisas sugerem que pode ter efeitos protetores contra o estresse oxidativo e pode apoiar a saúde cardiovascular. O composto é tipicamente solúvel em solventes polares, e sua estabilidade pode ser influenciada por fatores como pH e temperatura. Como um composto bioativo, Astragalosídeo II é de interesse tanto na pesquisa farmacológica quanto na medicina herbal, embora mais estudos sejam necessários para elucidar completamente seus mecanismos de ação e potencial terapêutico.

Fórmula: C₄₃H₇₀O₁₅

InChI: InChI=1/C43H70O15/c1-21(45)54-29-28(48)23(47)19-53-34(29)58-43(52)32(49)25(18-44)56-35(33(43)50)55-24-16-26-39(7)17-22(46)30(40(8)13-10-27(57-40)37(4,5)51)38(39,6)14-15-41(26)20-42(41)12-9-11-36(2,3)31(24)42/h22-35,44,46-52H,9-20H2,1-8H3/t22-,23+,24-,25+,26?,27-,28-,29+,30-,31?,32+,33-,34-,35+,38+,39-,40+,41?,42+,43+/m0/s1

Chave InChI: InChIKey=AYWNHWGQTMCQIV-PENCHUSISA-N

SMILES: C[C@]12[C@]3([C@]4([C@]5(C4)[C@@]([C@@H](O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)C3)(C(C)(C)[C@@H](O[C@H]7[C@H](OC(C)=O)[C@@H](O)[C@H](O)CO7)CC5)[H])CC[C@]1(C)[C@]([C@@H](O)C2)([C@]8(C)O[C@H](C(C)(C)O)CC8)[H])[H]

Sinónimos:

• (2S,3R,4S,5R)-4,5-dihydroxy-2-{[(2R,3S,4R,5R,6R)-3,4,5-trihydroxy-2-({(1R,2S,3aS,5S,9aR,12aR)-2-hydroxy-1-[(2R,5S)-5-(2-hydroxypropan-2-yl)-2-methyltetrahydrofuran-2-yl]-3a,6,6,12a-tetramethyltetradecahydro-1H-cyclopenta[a]cyclopropa[e]phenanthren-5-yl}oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl]oxy}tetrahydro-2H-pyran-3-yl acetate (non-preferred name)
• (3β,6α,16β,20R,24S)-3-[(2-O-Acetyl-β-<span class="text-smallcaps">D</smallcap>-xylopyranosyl)oxy]-20,24-epoxy-16,25-dihydroxy-9,19-cyclolanostan-6-yl β-<smallcap>D</span>-glucopyranoside
• 1H,19H-Cyclopropa[9,10]cyclopenta[a]phenanthrene, β-<span class="text-smallcaps">D</span>-glucopyranoside deriv.
• 9,19-Cyclolanostane, β-<span class="text-smallcaps">D</span>-glucopyranoside deriv.
• Astrasieversianin VIII
• NSC 641295
• astragalosideⅡ
• β-<span class="text-smallcaps">D</smallcap>-Glucopyranoside, (3β,6α,16β,20R,24S)-3-[(2-O-acetyl-β-<smallcap>D</span>-xylopyranosyl)oxy]-20,24-epoxy-16,25-dihydroxy-9,19-cyclolanostan-6-yl
• 1H,19H-Cyclopropa[9,10]cyclopenta[a]phenanthrene, β-D-glucopyranoside deriv.
• (3β,6α,16β,20R,24S)-3-[(2-O-Acetyl-β-D-xylopyranosyl)oxy]-20,24-epoxy-16,25-dihydroxy-9,19-cyclolanostan-6-yl β-D-glucopyranoside
• Astragaloside II
• 9,19-Cyclolanostane, β-D-glucopyranoside deriv.
• β-D-Glucopyranoside, (3β,6α,16β,20R,24S)-3-[(2-O-acetyl-β-D-xylopyranosyl)oxy]-20,24-epoxy-16,25-dihydroxy-9,19-cyclolanostan-6-yl
• Astragaloside II
• (3b,6a,16b,20r,24s)-3-((2-o-acetyl-beta-d-xylopyranosyl)oxy)-20,24-epoxy-16,25-dihydroxy-9,19-cyclolanostan-6-yl beta-d-glucopyranoside
• Astragaloside II USP/EP/BP
• Cyclosiversioside D
• Astragaloside II 84676-89-1
• Astragaloside II (Astrasieversianin VIII)
• Astragaloside B
• 16,25-dihydroxy-9,19-cyclolanostan-6-yl
• Astragalin Astragaloside II
• Cyclosieversioside D
• ASTRAGALOSIDE II(SH)
• 3-[(2-O-acetyl-β-D-xylopyranosyl)oxy]-20,24-epoxy-

β-​D-​Glucopyranoside, (3β,​6α,​16β,​20R,​24S)​-​3-​[(2-​O-​acetyl-​β-​D-​xylopyranosyl)​oxy]​-​20,​24-​epoxy-​16,​25-​dihydroxy-​9,​19-​cyclolanostan-​6-​yl

CAS: 84676-89-1

Fórmula: C₄₃H₇₀O₁₅

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 827.0069

Ref: IN-DA003NXK

Astragaloside II

CAS: 84676-89-1

Astragaloside II

Pureza: ≥98%

Peso molecular: 827.01g/mol

Ref: 54-BUP02941

Astragaloside II

CAS: 84676-89-1

Ref: 7W-GC0586

Astragaloside II

CAS: 84676-89-1

Astragaloside II can downregulate the expression of the P-gp and mdr1 gene, suppress phosphorylation of extracellular signal regulated kinase 1/2, p38 and c-Jun N-terminal kinase, suggests that Astragaloside II is a potent multidrug resistance (MDR) reversal agent and may be a potential adjunctive agent for hepatic cancer chemotherapy.

Fórmula: C₄₃H₇₀O₁₅

Pureza: 95%~99%

Cor e Forma: Powder

Peso molecular: 827.018

Ref: BP-BP0211

Astragaloside II

CAS: 84676-89-1

Astragaloside II: Potent for MDR, hepatic cancer therapy; boosts osteogenesis via BMP-2/MAPK, Smad1/5/8 pathways.

Fórmula: C₄₃H₇₀O₁₅

Pureza: 98.54% - 99.7%

Cor e Forma: Solid

Peso molecular: 827.01

Ref: TM-T3924

Astragaloside ii

CAS: 84676-89-1

Natural glycoside

Fórmula: C₄₃H₇₀O₁₅

Pureza: ≥ 98.0 % (HPLC)

Cor e Forma: Powder

Peso molecular: 827.02

Ref: 5G-89573

Astragaloside II

Produto Controlado

CAS: 84676-89-1

Applications Astragaloside II has cardioprotective effects as well as causing improvement in cognitive function. Used in the prevention of cardio-cerebral vascular diseases.
References Shaw, L et al.: PLoS One, 7, e3848 (2012); Kong, X. et al.: Int. J. Mol. Med., 29, 1090 (2012);

Fórmula: C₄₃H₇₀O₁₅

Cor e Forma: Neat

Peso molecular: 827.01

Ref: TR-A790140

Astragaloside II

CAS: 84676-89-1

Astragaloside II is a natural compound that has been shown to have anti-inflammatory effects in vitro and in vivo. Astragaloside II inhibits the production of inflammatory mediators by inhibiting phosphodiesterase and cyclooxygenase pathways. It also has a matrix effect on the cells, which may be due to its ability to activate protein kinase C. This compound also has an analytical method, which consists of HPLC with UV detection at 210 nm.

Fórmula: C₄₃H₇₀O₁₅

Pureza: Min. 95%

Cor e Forma: White To Off-White Solid

Peso molecular: 827.01 g/mol

Ref: 3D-MA09407