CAS 853910-61-9

NVP-BBD130

CAS: 853910-61-9

NVP-BBD130 is an orally administered, small molecule inhibitor of the mammalian target of rapamycin (mTOR) kinase. It was designed to selectively inhibit mTORC1. NVP-BBD130 has been shown to be a potent inhibitor of melanoma tumor growth in mice and also inhibits the activation of phosphoinositide 3-kinase and Akt. This compound has been evaluated in a pharmacokinetic study as well as a mouse model for melanoma with promising results. In addition, NVP-BBD130 was shown to have an acceptable safety profile in healthy volunteers.

Fórmula: C₂₈H₂₁N₅O

Pureza: Min. 95%

Peso molecular: 443.5 g/mol

Ref: 3D-DJB91061

NVP-BBD130

CAS: 853910-61-9

NVP-BBD130 is a stable, ATP-competitive, potent, orally active inhibitor of PI3K and mTOR.

Fórmula: C₂₈H₂₁N₅O

Cor e Forma: Solid

Peso molecular: 443.5

Ref: TM-T62603