CAS 857086-93-2

(1S,2R)-1-(6-bromo-2-methoxyquinolin-3-yl)-4-(methylamino)-2-(naphthalen-1-yl)-1-phenylbutan-2-ol

CAS: 857086-93-2

Fórmula: C₃₂H₃₁BrN₂O₂

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 555.5047

Ref: IN-DA00G3QK

(1S,2R)-Bedaquiline

CAS: 857086-93-2

(1S,2R)-Bedaquiline

Pureza: 98%

Peso molecular: 555.5g/mol

Ref: 54-OR1033208

(1S,2R)-1-(6-BROMO-2-METHOXYQUINOLIN-3-YL)-4-(DIMETHYLAMINO)-2-(NAPHTHALEN-1-YL)-1-PHENYLBUTAN-2-OL

CAS: 857086-93-2

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 555.5159912109375

Ref: 10-F824432

(AlphaR,BetaS)-Bedaquiline

Produto Controlado

CAS: 857086-93-2

Applications (αR,βS)-Bedaquiline is an intermediate in the synthesis of (αS,βR)-Bedaquiline (B119540), which is a diarylquinoline derivative that acts as a mycobacterial inhibitor. Bedaquiline shows promise as potential drug in the treatment of tuberculosis.
References Cheepsattayakorn, A., et al.: Anti-Infect. Drug. Discover.,7, 141 (2012); de Jonge M.R. et al.: Proteins, 67, 971 (2007); Diacon A.H. et al.: N. Eng. J. Med., 360, 2397 (2009);

Fórmula: C₃₂H₃₁BrN₂O₂

Cor e Forma: Neat

Peso molecular: 555.5

Ref: TR-B119535

(AlphaR,BetaS)-Bedaquiline

CAS: 857086-93-2

Fórmula: C₃₂H₃₁BrN₂O₂

Ref: TR-TRC-B119535

(±R,²S)-Bedaquiline

CAS: 857086-93-2

(±R,²S)-Bedaquiline is a diarylquinoline that is used in the treatment of drug-resistant tuberculosis. It has shown efficacy against multidrug-resistant tuberculosis and has been shown to reverse abnormal changes in bacterial DNA induced by injury. Bedaquiline displays antimycobacterial activity and is typically used as part of a multidrug regimen for the treatment of tuberculosis. Clinical trials have demonstrated that bedaquiline can improve pulmonary function, reduce the risk of decline in lung function, and improve survival rates for patients with drug-resistant tuberculosis.

Fórmula: C₃₂H₃₁BrN₂O₂

Pureza: Min. 95%

Peso molecular: 555.5 g/mol

Ref: 3D-HJB08693