CAS 86060-81-3

S-[(Acetilamino)metil]-N-[(9H-fluoren-9-ilmetoxi)carbonil]-L-cisteína

Descrição:

S-[(Acetilamino)metil]-N-[(9H-fluoren-9-ilmetoxi)carbonil]-L-cisteína, com o número CAS 86060-81-3, é um derivado sintético de aminoácidos que apresenta uma estrutura de cisteína modificada com um grupo acetilamino e um grupo protetor de fluorenilmetoxicarbonila (Fmoc). Este composto é caracterizado por sua capacidade de participar na síntese de peptídeos, particularmente na formação de ligações peptídicas devido à presença dos grupos funcionais amino e carboxila inerentes aos aminoácidos. O grupo Fmoc atua como um grupo protetor, permitindo a desproteção seletiva durante a síntese de peptídeos, o que é crucial na síntese de peptídeos em fase sólida. A modificação acetilamino melhora a solubilidade e estabilidade do composto, tornando-o adequado para várias aplicações bioquímicas. Além disso, a presença do átomo de enxofre no resíduo de cisteína permite reações redox potenciais e a formação de ligações dissulfeto, que são importantes na estrutura e função das proteínas. No geral, este composto é valioso no campo da química medicinal e da pesquisa de peptídeos.

Fórmula: C₂₁H₂₂N₂O₅S

InChI: InChI=1S/C21H22N2O5S/c1-13(24)22-12-29-11-19(20(25)26)23-21(27)28-10-18-16-8-4-2-6-14(16)15-7-3-5-9-17(15)18/h2-9,18-19H,10-12H2,1H3,(H,22,24)(H,23,27)(H,25,26)/t19-/m0/s1

Chave InChI: InChIKey=CSMYOORPUGPKAP-IBGZPJMESA-N

SMILES: C(OC(N[C@@H](CSCNC(C)=O)C(O)=O)=O)C1C=2C(C=3C1=CC=CC3)=CC=CC2

Sinónimos:

• (2R)-3-(Acetamidomethylsulfanyl)-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid
• (2R)-3-[(Acetamidomethyl)sulfanyl]-2-([[(9H-fluoren-9-yl)methoxy]carbonyl]amino)propanoic acid
• <span class="text-smallcaps">L</span>-Cysteine, S-[(acetylamino)methyl]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
• Fmoc-Cys(Acm)-OH
• Fmoc-L-Cys(Acm)-OH
• Fmoc-L-Cysteine(Acm)
• Fmoc-S-(acetamidomethyl)-L-cysteine
• N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-S-(acetamidomethyl)-<span class="text-smallcaps">L</span>-cysteine
• N-fmoc-S-acetamidomethyl L-cysteine
• S-[(Acetylamino)methyl]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-<span class="text-smallcaps">L</span>-cysteine
• S-[(acetylamino)methyl]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-cysteine
• S-[(acetylamino)methyl]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-cysteine
• N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-S-(acetamidomethyl)-L-cysteine

N-Fmoc-S-acetamidomethyl-L-cysteine, 95%

CAS: 86060-81-3

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Fórmula: C₂₁H₂₂N₂O₅S

Pureza: 95%

Peso molecular: 414.48

Ref: 02-H59306

Fmoc-Cys(Acm)-OH

CAS: 86060-81-3

Following Fmoc-SPPS, Acm can be converted on resin into the S-carbomethoxysulfenyl (Scm) group. Scm is cleaved by reduction with DTT, treatment with thiols yields unsymmetrical disulfides.

Fórmula: C₂₁H₂₂N₂O₅S

Pureza: 99.5%

Cor e Forma: White

Peso molecular: 414.48

Ref: 01-4006622

Fmoc-L-Cys(Acm)-OH

CAS: 86060-81-3

Fórmula: C₂₁H₂₂N₂O₅S

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 414.4748

Ref: IN-DA0036F0

Fmoc-Cys(Acm)-OH

CAS: 86060-81-3

Fórmula: C₂₁H₂₂N₂O₅S

Peso molecular: 414.47

Ref: 7W-GM1615

Fmoc-Cys(Acm)-OH

CAS: 86060-81-3

Fmoc-Cys(Acm)-OH

Pureza: 98%

Peso molecular: 414.47g/mol

Ref: 54-OR1013335

Fmoc-Cys(Acm)-OH, 10mM (in DMSO)

CAS: 86060-81-3

Fmoc-Cys(Acm)-OH, 10mM (in DMSO)

Pureza: ≥98%

Peso molecular: 414.47g/mol

Ref: 54-BUP19108

Fmoc-Cys(Acm)-OH

CAS: 86060-81-3

Fmoc-Cys(Acm)-OH (Fmoc-S-acetamidomethyl-L-cysteine) is a cysteine derivative.

Fórmula: C₂₁H₂₂N₂O₅S

Pureza: 99.89%

Cor e Forma: Solid

Peso molecular: 414.47

Ref: TM-T64327

Fmoc-Cys(Acm)-OH

CAS: 86060-81-3

Fórmula: C₂₁H₂₂N₂O₅S

Pureza: >95.0%(T)(HPLC)

Cor e Forma: White to Light yellow powder to crystal

Peso molecular: 414.48

Ref: 3B-A3534

Cysteine Impurity 12 (Fmoc-Cys(Acm)-OH)

CAS: 86060-81-3

Fórmula: C₂₁H₂₂N₂O₅S

Peso molecular: 414.48

Ref: 4Z-C-77125

Fmoc-Cys(Acm)-OH

CAS: 86060-81-3

M03396 - Fmoc-Cys(Acm)-OH

Fórmula: C₂₁H₂₂N₂O₅S

Pureza: 97%

Cor e Forma: Beige powder

Peso molecular: 414.48

Ref: 10-M03396

Fmoc-S-acetamidomethyl-L-cysteine

CAS: 86060-81-3

Fmoc-S-acetamidomethyl-L-cysteine is a peptide analog that has been shown to inhibit the growth of HIV in human prostate cells. It binds to the du-145 cell receptor and inhibits the proteolytic activity of HIV, which may be due to its ability to form an amide bond or disulfide bond with the Cys residue (Cys-X). Fmoc-S-acetamidomethyl-L-cysteine also inhibits the growth of prostate cancer cells by binding to human serum albumin. This drug has minimal toxicity in fetal bovine serum and is not toxic to most bacteria, as it does not bind with glycopeptides, antimicrobial peptides, or proteins. Fmoc-S-acetamidomethyl-L-cysteine has been shown to have biological properties against Trichophyton mentagrophytes and Staphylococcus a

Fórmula: C₂₁H₂₂N₂O₅S

Pureza: (Chiral Hplc) Min. 98 Area-%

Cor e Forma: White Off-White Powder

Peso molecular: 414.48 g/mol

Ref: 3D-FF47336

FMOC-S-Acetamido Methyl-L-Cysteine (Fmoc-Cys(Acm)-OH) extrapure, 98%

CAS: 86060-81-3

Fórmula: C₂₁H₂₂N₂O₅S

Pureza: min. 98.0%

Cor e Forma: White to Slight yellow to Beige, Powder, Clear

Peso molecular: 414.48

Ref: SR-97306