CAS 86386-73-4

Fluconazol

Descrição:

Fluconazol é um medicamento antifúngico usado principalmente para tratar infecções fúngicas, particularmente aquelas causadas por espécies de Candida e Cryptococcus neoformans. Pertence à classe dos antifúngicos triazólicos e atua inibindo a síntese de ergosterol, um componente essencial das membranas celulares fúngicas, interrompendo assim sua integridade e função. Fluconazol é caracterizado por sua alta biodisponibilidade oral, permitindo um tratamento sistêmico eficaz, e muitas vezes é administrado em formas oral e intravenosa. A substância é geralmente bem tolerada, com efeitos colaterais comuns que incluem distúrbios gastrointestinais e dor de cabeça. Tem uma meia-vida relativamente longa, permitindo a dosagem uma vez ao dia para muitas indicações. Fluconazol também é notável por sua capacidade de penetrar em vários tecidos do corpo, incluindo o sistema nervoso central, tornando-o eficaz no tratamento de meningite. No entanto, pode interagir com outros medicamentos devido aos seus efeitos sobre as enzimas hepáticas, exigindo monitoramento cuidadoso em pacientes em múltiplas terapias. No geral, Fluconazol é um agente crítico no manejo de infecções fúngicas sistêmicas e superficiais.

Fórmula: C₁₃H₁₂F₂N₆O

InChI: InChI=1S/C13H12F2N6O/c14-10-1-2-11(12(15)3-10)13(22,4-20-8-16-6-18-20)5-21-9-17-7-19-21/h1-3,6-9,22H,4-5H2

Chave InChI: InChIKey=RFHAOTPXVQNOHP-UHFFFAOYSA-N

SMILES: C(CN1C=NC=N1)(CN2C=NC=N2)(O)C3=C(F)C=C(F)C=C3

Sinónimos:

• 1-(2,4-Difluorophenyl)-1,1-bis[(1H-1,2,4-triazol-1-yl)methyl]methanol
• 1H-1,2,4-Triazole-1-ethanol, α-(2,4-difluorophenyl)-α-(1H-1,2,4-triazol-1-ylmethyl)-
• 2-(2,4-Difluorophenyl)-1,3-bis(1,2,4-triazol-1-yl)-propan-2-ol
• 2-(2,4-Difluorophenyl)-1,3-bis(1H-1,2,4-triazol-1-yl)propan-2-ol
• Alkanazole
• Biozolene
• Diflucan
• Difluconazole
• Elazor
• Floroxan
• Flucan
• Fluconal
• Flucostat
• Flumycon
• Flunazol
• Flusol
• Flutec
• Fluzon
• Fungican
• Fungicon
• Triconal
• Triflucan
• Uk 49858
• Zocon
• Zoltec
• a.-(2,4-Difluorophenyl)-a-(1H-1,2,4,-triazol-1-ylmethyl)-1H-1,2 ,4-triazole-1-ethanol
• α-(2,4-Difluorophenyl)-α-(1H-1,2,4-triazol-1-ylmethyl)-1H-1,2,4-triazole-1-ethanol

Fluconazole

CAS: 86386-73-4

Fórmula: C₁₃H₁₂F₂N₆O

Pureza: >98.0%(GC)(T)

Cor e Forma: White to Almost white powder to crystal

Peso molecular: 306.28

Ref: 3B-F0677

Fluconazole, 99%

CAS: 86386-73-4

Fluconazole, 86386-73-4, is a synthetic triazole, demethylase, and a cytochrome P-450 inhibitor with antifungal activity against some Candida infections. Learn more.

Fórmula: C₁₃H₁₂F₂N₆O

Pureza: 99%

Cor e Forma: White to pale cream, Powder

Peso molecular: 306.28

Ref: 02-J62015

Fluconazole 2.0 mg/ml in Methanol

CAS: 86386-73-4

Cor e Forma: Single Solution

Ref: 61-AMP0235.00-07

Fluconazole

CAS: 86386-73-4

Fluconazole

Fórmula: C₁₃H₁₂F₂N₆O

Pureza: 99.4%

Cor e Forma: White. To. Off-White

Peso molecular: 306.10407

Ref: 47-1174

FLUCONAZOLE CRS

CAS: 86386-73-4

FLUCONAZOLE CRS

Fórmula: C₁₃H₁₂F₂N₆O

Cor e Forma: Crystalline Powder. White. Powder.

Peso molecular: 306.2708

Ref: 41-Y0000557

FLUCONAZOLE FOR PEAK IDENTIFICATION CRS

CAS: 86386-73-4

FLUCONAZOLE FOR PEAK IDENTIFICATION CRS

Fórmula: C₁₃H₁₂F₂N₆O

Peso molecular: 306.2708

Ref: 41-Y0000558

Fluconazole impurity standard

CAS: 514222-44-7, 86386-73-4, 871550-15-1, 89429-59-4

Fluconazole impurity standard

Cor e Forma: White

Ref: 47-1175

Fluconazole

CAS: 86386-73-4

Anti-infective agents, nesoi

Fórmula: C₁₃H₁₂F₂N₆O

Cor e Forma: White Off-White Powder

Peso molecular: 306.10407

Ref: 45-1271700

1H-1,2,4-Triazole-1-ethanol, α-(2,4-difluorophenyl)-α-(1H-1,2,4-triazol-1-ylmethyl)-

CAS: 86386-73-4

Fórmula: C₁₃H₁₂F₂N₆O

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 306.2708

Ref: IN-DA000KX6

Fluconazole

CAS: 86386-73-4

Fluconazole (UK-49858) is a triazole antifungal agent that is used to treat oropharyngeal candidiasis and cryptococcal meningitis in AIDS.

Fórmula: C₁₃H₁₂F₂N₆O

Pureza: 98.57% - 99.17%

Cor e Forma: White Or Off White Crystalline Powder

Peso molecular: 306.27

Ref: TM-T1388

Fluconazole

CAS: 86386-73-4

Fluconazole

Pureza: ≥95%

Peso molecular: 306.27g/mol

Ref: 54-BUP15117

Fluconazole

CAS: 86386-73-4

Fórmula: C₁₃H₁₂F₂N₆O

Pureza: (non-aqueous titration) ≥ 98.5% (dried basis)

Cor e Forma: White to almost white powder or crystals

Peso molecular: 306.27

Ref: 7W-GA4147

Fluconazole (anhydrous)

CAS: 86386-73-4

Fluconazole (anhydrous)

Fórmula: C₁₃H₁₂F₂N₆O

Pureza: 98%

Cor e Forma: white solid

Peso molecular: 306.27078g/mol

Ref: 54-BI3858

Fluconazole

CAS: 86386-73-4

Fórmula: C₁₃H₁₂F₂N₆O

Cor e Forma: White To Off-White Solid

Peso molecular: 306.28

Ref: 4Z-F-142

Fluconazole-d4 (bismethylene-d4) (

CAS: 1124197-58-5, 86386-73-4

Pureza: 98 atom % D

Cor e Forma: White To Off-White Solid

Peso molecular: 310.30

Ref: 3U-D6143

Fluconazole

CAS: 86386-73-4

Cor e Forma: Neat

Ref: 86-MM0235.00

Fluconazole 100 µg/mL in Acetonitrile

CAS: 86386-73-4

Fórmula: C₁₃H₁₂F₂N₆O

Cor e Forma: Single Solution

Peso molecular: 306.27

Ref: 04-A13697500AL-100

Fluconazole

Produto Controlado

CAS: 86386-73-4

Fórmula: C₁₃H₁₂F₂N₆O

Cor e Forma: Neat

Peso molecular: 306.27

Ref: 04-C13697500

Fluconazole

CAS: 86386-73-4

Applications Fluconazole is used as an antifungal.
References Richard, K. et al.: Antimicrob. Ag. Chemother., 27, 832 (1985),

Fórmula: C₁₃H₁₂F₂N₆O

Cor e Forma: Neat

Peso molecular: 306.27

Ref: TR-F421000

Fluconazole - Bio-X ™

CAS: 86386-73-4

Fluconazole is an antifungal drug used to treat a wide range of fungal infections. Fluconazole is a cytochrome demethylase system inhibitor that acts by interfering with β-glucan biosynthesis. It has been shown to be effective in treating candidemia, a life-threatening form of candidiasis caused by the fungus Candida albicans. Fluconazole seems to be more effective than amphotericin B in treating some isolates of C. albicans, making it a valuable tool in the fight against this deadly fungal infection, although due to the increase of antimicrobial resistance, fluconazole has been studied in combination with other drugs (e.g. farnesol).

Fórmula: C₁₃H₁₂F₂N₆O

Pureza: (%) Min. 95%

Cor e Forma: Powder

Peso molecular: 306.27 g/mol

Ref: 3D-BF164466