CAS 86393-33-1

Ácido fluoroquinolônico

Descrição:

Ácido fluoroquinolônico, identificado pelo seu número CAS 86393-33-1, é um composto sintético pertencente à classe de antibióticos fluoroquinolonas. Esta substância é caracterizada por sua atividade antibacteriana de amplo espectro, direcionando-se principalmente à girase do DNA bacteriano e à topoisomerase IV, que são essenciais para a replicação e transcrição do DNA bacteriano. Ácido fluoroquinolônico exibe um alto grau de lipofilicidade, permitindo que penetre efetivamente nas membranas celulares bacterianas. Sua estrutura química geralmente inclui um núcleo bicíclico com um átomo de flúor, que aumenta sua potência e espectro de atividade contra bactérias Gram-positivas e Gram-negativas. Além disso, este composto pode apresentar graus variados de solubilidade em água e solventes orgânicos, influenciando suas propriedades farmacocinéticas. Ácido fluoroquinolônico é frequentemente estudado por suas potenciais aplicações terapêuticas, particularmente no tratamento de infecções causadas por cepas bacterianas resistentes. No entanto, assim como outras fluoroquinolonas, pode estar associado a efeitos colaterais, incluindo possíveis impactos na saúde dos tendões e no sistema nervoso central, exigindo consideração cuidadosa em seu uso clínico.

Fórmula: C₁₃H₉ClFNO₃

InChI: InChI=1S/C13H9ClFNO3/c14-9-4-11-7(3-10(9)15)12(17)8(13(18)19)5-16(11)6-1-2-6/h3-6H,1-2H2,(H,18,19)

Chave InChI: InChIKey=ISPVACVJFUIDPD-UHFFFAOYSA-N

SMILES: C(O)(=O)C1=CN(C=2C(C1=O)=CC(F)=C(Cl)C2)C3CC3

Sinónimos:

• 1-Cyclopropyl-1,4-dihydro-4-oxo-6-fluoro-7-chloro-3-quinolinecarboxylic acid
• 1-Cyclopropyl-6-fluoro-7-chloro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid
• 1-Cyclopropyl-6-fluoro-7-chloro-1,4-dihydro-4-oxoquinolin-3-carboxylic acid
• 1-Cyclopropyl-7-chloro-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid
• 3-Quinolinecarboxylic acid, 7-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-
• 7-Chloro-1-Cyclopropyl-6-Fluoro-1,4-Dihydro-4-Oxoquinoline-3-Carboxylic Acid
• 7-Chloro-1-Cyclopropyl-6-Fluoro-4-Oxo-1,4-Dihydroquinoline-3-Carboxylate
• 7-Chloro-1-Cyclopropyl-6-Fluoro-4-Oxo-1,4-Dihydroquinoline-3-Carboxylic Acid
• 7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid
• 7-Chloro-1-cyclopropyl-6-fluoro-3-carboxy-1,4-dihydro-4-oxoquinoline
• 7-Chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid
• 7-Chloro-1-cyclopropyl-6-fluoroquinolin-4-one-3-carboxylic acid

7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid

CAS: 86393-33-1

Fórmula: C₁₃H₉ClFO₃N

Pureza: >98.0%(T)(HPLC)

Cor e Forma: White to Light yellow powder to crystal

Peso molecular: 281.67

Ref: 3B-C2293

CIPROFLOXACIN IMPURITY A RS

CAS: 86393-33-1

CIPROFLOXACIN IMPURITY A RS

Ref: 41-ICRS070005

CIPROFLOXACIN IMPURITY A CRS

CAS: 86393-33-1

CIPROFLOXACIN IMPURITY A CRS

Fórmula: C₁₃H₉ClFNO₃

Peso molecular: 281.6669

Ref: 41-C2190050

Fluoroquinolonic Acid

CAS: 86393-33-1

Compounds (excluding drugs and pesticides) containing a

Fórmula: C₁₃H₉ClFNO₃

Cor e Forma: Beige Powder

Peso molecular: 281.0255

Ref: 45-1278302

Ciprofloxacin EP IMpurity A

CAS: 86393-33-1

Ciprofloxacin EP IMpurity A (Fluoroquinolonic Acid) is an antibiotic and antimicrobial agent.

Fórmula: C₁₃H₉ClFNO₃

Pureza: 99.92%

Cor e Forma: Solid

Peso molecular: 281.67

Ref: TM-T1733

7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid

CAS: 86393-33-1

Fórmula: C₁₃H₉ClFNO₃

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 281.6669

Ref: IN-DA0034E6

7-Chloro-1-cyclopropyl-1,4-dihydro-6-fluoro-4-oxoquinoline-3-carboxylic acid

CAS: 86393-33-1

7-Chloro-1-cyclopropyl-1,4-dihydro-6-fluoro-4-oxoquinoline-3-carboxylic acid

Fórmula: C₁₃H₉ClFNO₃

Pureza: ≥95%

Cor e Forma: faint brown powder

Peso molecular: 281.67g/mol

Ref: 54-PC7236

Ciprofloxacin EP Impurity A

CAS: 86393-33-1

Fórmula: C₁₃H₉ClFNO₃

Cor e Forma: White To Off-White Solid

Peso molecular: 281.67

Ref: 4Z-C-085

Ciprofloxacin EP IMpurity A

CAS: 86393-33-1

Ciprofloxacin EP IMpurity A

Pureza: ≥95%

Peso molecular: 281.67g/mol

Ref: 54-BUP18431

7-Chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid

CAS: 86393-33-1

Pureza: 97.0%

Cor e Forma: Solid

Peso molecular: 281.6700134277344

Ref: 10-F011623

7-Chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid (Fluoroquinolonic Acid)

Produto Controlado

CAS: 86393-33-1

Fórmula: C₁₃H₉ClFNO₃

Cor e Forma: Neat

Peso molecular: 281.67

Ref: 86-MM0018.01

7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic Acid

Produto Controlado

CAS: 86393-33-1

Impurity Ciprofloxacin EP Impurity A; Enrofloxacin impurity A
Applications 7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic Acid (Ciprofloxacin EP Impurity A) is a metabolite of Ciprofloxacin, a fluorinated quinolone antibacterial.
References Siefert, H.M., et al.: Arzneim.-Forsch., 36, 1496 (1986), Zhi, C., J. Med. Chem., 49, 1455 (2006), Trefi, S., et al.: J. Pharm. Biomed. Anal., 44, 743 (2007),

Fórmula: C₁₃H₉ClFNO₃

Cor e Forma: Off-White To Light Yellow

Peso molecular: 281.67

Ref: TR-C365135

Enrofloxacin EP Impurity A

CAS: 86393-33-1

Fórmula: C₁₃H₉ClFNO₃

Peso molecular: 281.7

Ref: ST-EA-CP-E24001

Ciprofloxacin EP Impurity A

CAS: 86393-33-1

Fórmula: C₁₃H₉ClFNO₃

Peso molecular: 281.67

Ref: ST-EA-CP-C22001

Ciprofloxacin impurity A

CAS: 86393-33-1

Ciprofloxacin impurity A is an analog of ciprofloxacin and is a pharmaceutical preparation that belongs to the class of fluoroquinolones. It has been shown to be active against P. aeruginosa and other gram-negative bacteria in wastewater treatment systems. Ciprofloxacin impurity A is activated by ethylene diamine and can be eluted with acidic solvents. It also inhibits tumor cell line growth through adsorption mechanism and is used as a drug for cancer chemoprevention in combination with malic acid.

Fórmula: C₁₃H₉ClFNO₃

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 281.67 g/mol

Ref: 3D-IC58175